OXFYY (Oxford Nanopore Technologies) Profitability Rank: 2 (As of Dec. 2025) — 33% Below Median

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OXFYY Oxford Nanopore Technologies PLC OXFYY
50 GF Score
Price $6.05
GF Value $10.32
Valuation Significantly Undervalued
! 3 Warning Signs
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What is Oxford Nanopore Technologies Profitability Rank?

Oxford Nanopore Technologies OXFYY 50 Profitability Rank is 2 as of Dec. 2025, which is 33% below its 10-year median of 3.00. GuruFocus rates OXFYY with a GF Score™ of 50/100 and a GF Value™ of $10.32 (Significantly Undervalued). The stock has 3 warning signs investors should review.

Oxford Nanopore Technologies has the Profitability Rank of 2. It has had trouble to make a profit.

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way. It is rated on a scale of 1 to 10 and is based on these factors:

1. Operating Margin %
2. Piotroski F-Score
3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.
4. Consistency of the profitability
5. Predictability Rank

A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Oxford Nanopore Technologies's Operating Margin % for the quarter that ended in Dec. 2025 was -65.51%. As of today, Oxford Nanopore Technologies's Piotroski F-Score is 4.


Oxford Nanopore Technologies Profitability Rank Related Terms


OXFYY vs VRTX, REGN, RVMD: Profitability Rank Comparison

For the Biotechnology subindustry, Oxford Nanopore Technologies's Profitability Rank, along with its competitors' market caps and Profitability Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Oxford Nanopore Technologies Profitability Rank vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Oxford Nanopore Technologies's Profitability Rank distribution charts can be found below:

* The bar in red indicates where Oxford Nanopore Technologies's Profitability Rank falls into.


OXFYY
50GF Score
Oxford Nanopore Technologies PLC OXFYY
Profitability Rank is just one metric. See GF Score™, valuation, warning signs, and more.
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Oxford Nanopore Technologies Profitability Rank Calculation

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way.

The rank is rated on a scale of 1 to 10. A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Oxford Nanopore Technologies has the Profitability Rank of 2. It has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength. But if a company is consistently profitable, its financial strength will be stronger.

Profitability Rank is based on these factors:

1. Operating Margin %

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Oxford Nanopore Technologies's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as:

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-103.748 / 158.367
=-65.51 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2. Piotroski F-Score

The zones of discrimination were as such:

Good or high score = 8 or 9
Bad or low score = 0 or 1

Oxford Nanopore Technologies has an F-score of 4 indicating the company's financial situation is typical for a stable company.

3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.

Good Sign:

Oxford Nanopore Technologies PLC operating margin is expanding. Margin expansion is usually a good sign.

4. Consistency of the profitability

5. Predictability Rank

Frequently Asked Questions Learn more about Profitability Rank →
What does a Profitability Rank of 2 mean?
Oxford Nanopore Technologies (OXFYY) has a Profitability Rank of 2 as of Dec. 2025. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Oxford Nanopore Technologies and its competitors. This is 33% below median its historical median of 3.00. Over the past decade, Oxford Nanopore Technologies' Profitability Rank has ranged from 2.00 to 3.00.
Is Oxford Nanopore Technologies' Profitability Rank too high?
Oxford Nanopore Technologies' current Profitability Rank of 2 is 33% below median its 10-year median of 3.00. Over the past 10 years, this metric has ranged from a low of 2.00 to a high of 3.00. Overall, Oxford Nanopore Technologies has a GF Score™ of 50/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Oxford Nanopore Technologies' Profitability Rank compare to VRTX and REGN?
Oxford Nanopore Technologies' Profitability Rank of 2 can be compared against companies in the Biotechnology industry. Historically, Oxford Nanopore Technologies' own Profitability Rank has ranged from 2.00 to 3.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Profitability Rank for a Biotechnology company?
A good Profitability Rank depends on the Biotechnology industry context. However, Profitability Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Profitability Rank mean?
A high Profitability Rank can signal that a stock is expensive relative to its fundamentals. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Oxford Nanopore Technologies and its competitors. Oxford Nanopore Technologies's current Profitability Rank is 2, which is 33% below median its own 10-year median of 3.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Oxford Nanopore Technologies stock overvalued right now?
Based on GuruFocus' analysis, Oxford Nanopore Technologies (OXFYY) is currently considered Significantly Undervalued. The stock's GF Value™ is $10.32, compared to a current price of $6.05 — trading 41.4% below its estimated fair value. The current Profitability Rank is 2, which is 33% below median its 10-year median of 3.00. Oxford Nanopore Technologies' overall GF Score™ is 50/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Profitability Rank calculated?
Profitability Rank is calculated from a company's financial statements. For Oxford Nanopore Technologies (OXFYY), the current Profitability Rank is 2 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Oxford Nanopore Technologies (OXFYY) Overvalued in 2026?

Based on GuruFocus' analysis, Oxford Nanopore Technologies stock appears to be undervalued. The current stock price of $6.05 is trading 41.4% below its estimated GF Value™ of $10.32. GuruFocus considers Oxford Nanopore Technologies to be Significantly Undervalued.

Key valuation signals for OXFYY:

  • Profitability Rank: 2 (33% below median its 10-year median of 3.00)
  • GF Value™: $10.32 vs. price of $6.05 (41.4% below fair value)
  • GF Score™: 50/100 with 3 warning signs

No single metric tells the full story. See the OXFYY stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Oxford Nanopore Technologies Business Description

Address Edmund Halley Road, Gosling Building, Oxford Science Park, Oxford, Oxfordshire, GBR, OX4 4DQ
Oxford Nanopore Technologies PLC is involved in researching, developing, manufacturing and commercializing deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) sequencing technology that provides rich data, is fast, accessible and easy to use, and which allows the real-time analysis of DNA or RNA. It has developed and brought to market a new generation molecular sensing platform based on nanopores. The first application is DNA/RNA sequencing and the platform is also being developed for the analysis of proteins and metabolites. It operates in single segment of providing products and services related to the sale and use of its nanopore-based sensing technology. Geographically its operations are spread across EMES, AMR, and APAC.
50GF Score

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Profitability Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$6.05
Price
$10.32
GF Value