Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. Oxford Nanopore Technologies's annualized net income for the quarter that ended in Dec. 2025 was $-196.5 Mil. Oxford Nanopore Technologies's average shareholder tangible equity for the quarter that ended in Dec. 2025 was $592.9 Mil. Therefore, Oxford Nanopore Technologies's annualized Return-on-Tangible-Equity for the quarter that ended in Dec. 2025 was -33.15%.
The historical rank and industry rank for Oxford Nanopore Technologies's Return-on-Tangible-Equity or its related term are showing as below:
OXFYY'
s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -62.93 Med: -34.75 Max: -13.54
Current: -30.64
During the past 8 years, Oxford Nanopore Technologies's highest Return-on-Tangible-Equity was -13.54%. The lowest was -62.93%. And the median was -34.75%.
OXFYY's Return-on-Tangible-Equity is ranked better than 56.55% of 1199
companies
in the Biotechnology industry
Industry Median: -42.4
vs OXFYY: -30.64
Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.
Be Aware
Net Income is used.
Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.
Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.
Oxford Nanopore Technologies Return-on-Tangible-Equity Related Terms
Oxford Nanopore Technologies Return-on-Tangible-Equity Historical Data
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
OXFYY vs VRTX, REGN, ALNY: Return-on-Tangible-Equity Comparison
For the Biotechnology subindustry, Oxford Nanopore Technologies's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Oxford Nanopore Technologies Return-on-Tangible-Equity vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Oxford Nanopore Technologies's Return-on-Tangible-Equity distribution charts can be found below:
* The bar in red indicates where Oxford Nanopore Technologies's Return-on-Tangible-Equity falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data,
the net income data used here is two times the semi-annual (Dec. 2025) net income data.
Return-on-Tangible-Equity is displayed in the 10-year financial page.
What does a Return-on-Tangible-Equity of -33.15% mean?
Oxford Nanopore Technologies (OXFYY) has a Return-on-Tangible-Equity of -33.15% as of Dec. 2025. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Oxford Nanopore Technologies and its competitors. According to the industry distribution chart, Oxford Nanopore Technologies ranks #521 out of 1199 companies in the Biotechnology industry, placing it in the top 43.5%.
Is Oxford Nanopore Technologies' Return-on-Tangible-Equity too high?
Oxford Nanopore Technologies' current Return-on-Tangible-Equity is -33.15%. Based on the distribution chart, Oxford Nanopore Technologies ranks #521 out of 1199 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Oxford Nanopore Technologies has a GF Score™ of 50/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Oxford Nanopore Technologies' Return-on-Tangible-Equity compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Oxford Nanopore Technologies ranks #521 out of 1199 companies for Return-on-Tangible-Equity. This puts Oxford Nanopore Technologies in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Oxford Nanopore Technologies and its competitors. Oxford Nanopore Technologies's current Return-on-Tangible-Equity is -33.15%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Oxford Nanopore Technologies stock overvalued right now?
Based on GuruFocus' analysis, Oxford Nanopore Technologies (OXFYY) is currently considered Significantly Undervalued. The stock's GF Value™ is $10.35, compared to a current price of $6.50 — trading 37.2% below its estimated fair value. The current Return-on-Tangible-Equity is -33.15%. Oxford Nanopore Technologies' overall GF Score™ is 50/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For Oxford Nanopore Technologies (OXFYY), the current Return-on-Tangible-Equity is -33.15% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Oxford Nanopore Technologies (OXFYY) Overvalued in 2026?
Based on GuruFocus' analysis, Oxford Nanopore Technologies stock appears to be undervalued.
The current stock price of $6.50 is trading 37.2% below its estimated GF Value™ of $10.35.
GuruFocus considers Oxford Nanopore Technologies to be Significantly Undervalued.
Key valuation signals for OXFYY:
Return-on-Tangible-Equity: -33.15%
GF Value™: $10.35 vs. price of $6.50 (37.2% below fair value)
No single metric tells the full story. See the OXFYY stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Oxford Nanopore Technologies PLC is involved in researching, developing, manufacturing and commercializing deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) sequencing technology that provides rich data, is fast, accessible and easy to use, and which allows the real-time analysis of DNA or RNA. It has developed and brought to market a new generation molecular sensing platform based on nanopores. The first application is DNA/RNA sequencing and the platform is also being developed for the analysis of proteins and metabolites. It operates in single segment of providing products and services related to the sale and use of its nanopore-based sensing technology. Geographically its operations are spread across EMES, AMR, and APAC.
50GF Score
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