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PfizerXSWX:PFE +1.17%63 Debt-to-EBITDA is 2.92 as of Mar. 2026, which is 4% above its 10-year median of 2.82. GuruFocus rates XSWX:PFE with a GF Score™ of 63/100 and a GF Value™ of CHF21.05 (Fairly Valued). The stock has 5 warning signs investors should review. Among 690 Drug Manufacturers companies, Pfizer ranks worse than 74.78% on this metric.
Debt-to-EBITDA measures a company's ability to pay off its debt.
A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt. According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.
The historical rank and industry rank for Pfizer's Debt-to-EBITDA or its related term are showing as below:
XSWX:PFE'
s Debt-to-EBITDA Range Over the Past 10 Years
Min: 0.85 Med: 2.82 Max: 7.41
Current: 3.71
During the past 13 years, the highest Debt-to-EBITDA Ratio of Pfizer was 7.41. The lowest was 0.85. And the median was 2.82.
XSWX:PFE's Debt-to-EBITDA is ranked worse than 74.78% of 690
companies
in the Drug Manufacturers industry
Industry Median: 1.67
vs XSWX:PFE: 3.71
A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt.
According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.
Pfizer Debt-to-EBITDA Related Terms
Pfizer Debt-to-EBITDA Historical Data
* Premium members only.
The historical data trend for Pfizer's Debt-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
XSWX:PFE vs GILD, BMY, AMGN: Debt-to-EBITDA Comparison
For the Drug Manufacturers - General subindustry, Pfizer's Debt-to-EBITDA, along with its competitors' market caps and Debt-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Pfizer Debt-to-EBITDA vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, Pfizer's Debt-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Pfizer's Debt-to-EBITDA falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Debt-to-EBITDA, the EBITDA of the last fiscal year is used. In calculating the annualized quarterly data,
the EBITDA data used here is four times the quarterly (Mar. 2026) EBITDA data.
Pfizer (XSWX:PFE) has a Debt-to-EBITDA of 2.92 as of Mar. 2026. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on Pfizer. This is near median its historical median of 2.82. Over the past decade, Pfizer's Debt-to-EBITDA has ranged from 0.85 to 7.41. According to the industry distribution chart, Pfizer ranks #516 out of 690 companies in the Drug Manufacturers industry, placing it in the top 74.8%.
Is Pfizer's Debt-to-EBITDA too high?
Pfizer's current Debt-to-EBITDA of 2.92 is near median its 10-year median of 2.82. Over the past 10 years, this metric has ranged from a low of 0.85 to a high of 7.41. The Drug Manufacturers industry median Debt-to-EBITDA is 1.67. Pfizer's value of 2.92 is 74.9% above this industry median. Based on the distribution chart, Pfizer ranks #516 out of 690 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, Pfizer has a GF Score™ of 63/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Pfizer's Debt-to-EBITDA compare to GILD and BMY?
According to the Drug Manufacturers industry distribution chart, Pfizer ranks #516 out of 690 companies for Debt-to-EBITDA. This places Pfizer in the lower half of its industry. The industry median Debt-to-EBITDA is 1.67. Pfizer's value of 2.92 is 74.9% above this benchmark. Historically, Pfizer's own Debt-to-EBITDA has ranged from 0.85 to 7.41 over the past decade. While the company's 10-year median is 2.82 vs. the industry median of 1.67, Pfizer has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Debt-to-EBITDA for a Drug Manufacturers company?
The median Debt-to-EBITDA among Drug Manufacturers companies is 1.67, based on 690 companies in the industry. Companies in the top quartile (top 25%) have a Debt-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, Debt-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Pfizer's current Debt-to-EBITDA of 2.92 is 74.9% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Debt-to-EBITDA mean?
A high Debt-to-EBITDA can signal that a stock is expensive relative to its fundamentals. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on Pfizer. For the Drug Manufacturers industry, the median Debt-to-EBITDA is 1.67 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Pfizer's current Debt-to-EBITDA is 2.92, which is near median its own 10-year median of 2.82. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Pfizer stock overvalued right now?
Based on GuruFocus' analysis, Pfizer (XSWX:PFE) is currently considered Fairly Valued. The stock's GF Value™ is CHF21.05, compared to a current price of CHF19.81 — trading 5.9% below its estimated fair value. The current Debt-to-EBITDA is 2.92, which is near median its 10-year median of 2.82 and 74.9% above the Drug Manufacturers industry median of 1.67. Pfizer's overall GF Score™ is 63/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Debt-to-EBITDA calculated?
Debt-to-EBITDA is calculated from a company's financial statements. For Pfizer (XSWX:PFE), the current Debt-to-EBITDA is 2.92 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Pfizer (XSWX:PFE) Overvalued in 2026?
Based on GuruFocus' analysis, Pfizer stock appears to be undervalued.
The current stock price of CHF19.81 is trading 5.9% below its estimated GF Value™ of CHF21.05.
GuruFocus considers Pfizer to be Fairly Valued.
Key valuation signals for XSWX:PFE:
Debt-to-EBITDA: 2.92 (near median its 10-year median of 2.82)
GF Value™: CHF21.05 vs. price of CHF19.81 (5.9% below fair value)
Industry Position: 74.9% above the Drug Manufacturers median (#516 of 690)
No single metric tells the full story. See the XSWX:PFE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Pfizer is one of the world's largest pharmaceutical firms, with annual sales of roughly $60 billion. While it historically sold many types of healthcare products and chemicals, now prescription drugs and vaccines account for the majority of sales. Top sellers include pneumococcal vaccine Prevnar 13 and cardiology drugs Vyndaqel and Eliquis. Pfizer sells these products globally, with international sales representing 40% of total sales. Within international sales, emerging markets are a major contributor.
63GF Score
Get the complete analysis for XSWX:PFE
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