AMPE (Ampio Pharmaceuticals) E10: $-101.56 (As of Dec. 2023)


What is Ampio Pharmaceuticals E10?

Ampio Pharmaceuticals AMPE -71.39% E10 is $-101.56 as of Dec. 2023.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Ampio Pharmaceuticals's adjusted earnings per share data for the three months ended in Dec. 2023 was $-2.480. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-101.56 for the trailing ten years ended in Dec. 2023.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

As of today (2026-06-27), Ampio Pharmaceuticals's current stock price is $0.1831. Ampio Pharmaceuticals's E10 for the quarter that ended in Dec. 2023 was $-101.56. Ampio Pharmaceuticals's Shiller PE Ratio of today is .


Ampio Pharmaceuticals  (OTCPK:AMPE) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Ampio Pharmaceuticals E10 Related Terms


Ampio Pharmaceuticals E10 Historical Data

* Premium members only.

The historical data trend for Ampio Pharmaceuticals's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ampio Pharmaceuticals E10 Chart

Ampio Pharmaceuticals Annual Data
Trend Dec14 Dec15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only -153.05 -140.63 -123.11 -120.85 -101.56

Ampio Pharmaceuticals Quarterly Data
Mar19 Jun19 Sep19 Dec19 Mar20 Jun20 Sep20 Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -120.85 -119.14 -113.95 -108.79 -101.56

AMPE vs EFTR, VBIVQ, VRTX: E10 Comparison

For the Biotechnology subindustry, Ampio Pharmaceuticals's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ampio Pharmaceuticals Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ampio Pharmaceuticals's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Ampio Pharmaceuticals's Shiller PE Ratio falls into.



Ampio Pharmaceuticals E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Ampio Pharmaceuticals's adjusted earnings per share data for the three months ended in Dec. 2023 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Dec. 2023 (Change)*Current CPI (Dec. 2023)
=-2.48/306.7460*306.7460
=-2.480

Current CPI (Dec. 2023) = 306.7460.

Ampio Pharmaceuticals Quarterly Data

per share eps CPI Adj_EPS
201403 -69.000 236.293 -89.573
201406 -51.000 238.343 -65.637
201409 -54.000 238.031 -69.589
201412 -57.000 234.812 -74.462
201503 -42.000 236.119 -54.563
201506 -42.000 238.638 -53.987
201509 -42.000 237.945 -54.144
201512 -60.000 236.525 -77.813
201603 -39.000 238.132 -50.237
201606 -30.000 241.018 -38.181
201609 -21.000 241.428 -26.682
201612 -18.000 241.432 -22.869
201703 -9.000 243.801 -11.324
201706 -12.000 244.955 -15.027
201709 -18.000 246.819 -22.370
201712 -195.000 246.524 -242.635
201803 81.000 249.554 99.563
201806 -9.000 251.989 -10.956
201809 -6.000 252.439 -7.291
201812 27.000 251.233 32.966
201903 -15.000 254.202 -18.101
201906 1.063 256.143 1.273
201909 -15.000 256.759 -17.920
201912 -12.000 256.974 -14.324
202003 -12.000 258.115 -14.261
202006 -6.000 257.797 -7.139
202009 -6.000 260.280 -7.071
202012 -6.000 260.474 -7.066
202103 -6.000 264.877 -6.948
202106 -6.000 271.696 -6.774
202109 -5.800 274.310 -6.486
202112 -13.000 278.802 -14.303
202203 -9.200 287.504 -9.816
202206 -6.600 296.311 -6.832
202209 -10.060 296.808 -10.397
202212 -3.440 296.797 -3.555
202303 -5.200 301.836 -5.285
202306 -1.800 305.109 -1.810
202309 -1.530 307.789 -1.525
202312 -2.480 306.746 -2.480

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-101.56 mean?
Ampio Pharmaceuticals (AMPE) has a E10 of $-101.56 as of Dec. 2023. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Ampio Pharmaceuticals and its competitors.
Is Ampio Pharmaceuticals' E10 too high?
Ampio Pharmaceuticals' current E10 is $-101.56.
How does Ampio Pharmaceuticals' E10 compare to EFTR and VBIVQ?
Ampio Pharmaceuticals' E10 of $-101.56 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Ampio Pharmaceuticals and its competitors. Ampio Pharmaceuticals's current E10 is $-101.56. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ampio Pharmaceuticals stock overvalued right now?
Ampio Pharmaceuticals (AMPE) has a current E10 of $-101.56. The current E10 is $-101.56. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Ampio Pharmaceuticals (AMPE), the current E10 is $-101.56 as of Dec. 2023. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Ampio Pharmaceuticals Business Description

Address 9800 Mount Pyramid Court, Suite 400, Englewood, CO, USA, 80112
Ampio Pharmaceuticals Inc is a biopharmaceutical company. It is focused on the development of a potential treatment for osteoarthritis of the knee (OAK) as part of its OA-201 development program (OA-201 program or OA-201).