BPTH (Bio-Path Holdings) E10: $-149.12 (As of Mar. 2026)


What is Bio-Path Holdings E10?

Bio-Path Holdings BPTH +21.43% E10 is $-149.12 as of Mar. 2026. The stock has 1 warning sign investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Bio-Path Holdings's adjusted earnings per share data for the three months ended in Mar. 2026 was $-0.030. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-149.12 for the trailing ten years ended in Mar. 2026.

During the past 3 years, the average E10 Growth Rate was 6.40% per year. During the past 5 years, the average E10 Growth Rate was 4.40% per year. During the past 10 years, the average E10 Growth Rate was 2.60% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Bio-Path Holdings was 6.40% per year. The lowest was -0.40% per year. And the median was 2.55% per year.

As of today (2026-06-25), Bio-Path Holdings's current stock price is $0.0425. Bio-Path Holdings's E10 for the quarter that ended in Mar. 2026 was $-149.12. Bio-Path Holdings's Shiller PE Ratio of today is .


Bio-Path Holdings  (OTCPK:BPTH) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Bio-Path Holdings E10 Related Terms


Bio-Path Holdings E10 Historical Data

* Premium members only.

The historical data trend for Bio-Path Holdings's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Bio-Path Holdings E10 Chart

Bio-Path Holdings Annual Data
Trend Dec15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only -220.29 -218.79 -215.45 -199.88 -179.69

Bio-Path Holdings Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -179.69 -171.28 -167.41 -157.66 -149.12

BPTH vs ADAPY, ZVSA, CLSDQ: E10 Comparison

For the Biotechnology subindustry, Bio-Path Holdings's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Bio-Path Holdings Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Bio-Path Holdings's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Bio-Path Holdings's Shiller PE Ratio falls into.



Bio-Path Holdings E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Bio-Path Holdings's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-0.03/330.2130*330.2130
=-0.030

Current CPI (Mar. 2026) = 330.2130.

Bio-Path Holdings Quarterly Data

per share eps CPI Adj_EPS
201603 -80.000 238.132 -110.934
201606 -80.000 241.018 -109.606
201609 -80.000 241.428 -109.420
201612 -52.000 241.432 -71.122
201703 -16.000 243.801 -21.671
201706 -124.000 244.955 -167.159
201709 -100.000 246.819 -133.788
201712 -79.800 246.524 -106.890
201803 -67.600 249.554 -89.449
201806 -59.200 251.989 -77.577
201809 -107.600 252.439 -140.751
201812 -53.000 251.233 -69.662
201903 -17.800 254.202 -23.123
201906 -17.400 256.143 -22.432
201909 -15.600 256.759 -20.063
201912 -14.600 256.974 -18.761
202003 -18.000 258.115 -23.028
202006 -11.000 257.797 -14.090
202009 -16.000 260.280 -20.299
202012 -11.400 260.474 -14.452
202103 -8.600 264.877 -10.721
202106 -5.200 271.696 -6.320
202109 -5.800 274.310 -6.982
202112 -11.800 278.802 -13.976
202203 -9.400 287.504 -10.796
202206 -8.400 296.311 -9.361
202209 -9.800 296.808 -10.903
202212 -10.520 296.797 -11.704
202303 -13.250 301.836 -14.496
202306 -10.640 305.109 -11.515
202309 -6.360 307.789 -6.823
202312 -4.290 306.746 -4.618
202403 -4.880 312.332 -5.159
202406 -1.160 314.175 -1.219
202409 -0.700 315.301 -0.733
202412 -0.477 315.605 -0.499
202503 -0.400 319.799 -0.413
202506 -0.550 322.561 -0.563
202509 -0.110 324.800 -0.112
202603 -0.030 330.213 -0.030

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-149.12 mean?
Bio-Path Holdings (BPTH) has a E10 of $-149.12 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Bio-Path Holdings and its competitors.
Is Bio-Path Holdings' E10 too high?
Bio-Path Holdings' current E10 is $-149.12.
How does Bio-Path Holdings' E10 compare to ADAPY and ZVSA?
Bio-Path Holdings' E10 of $-149.12 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Bio-Path Holdings and its competitors. Bio-Path Holdings's current E10 is $-149.12. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Bio-Path Holdings stock overvalued right now?
Bio-Path Holdings (BPTH) has a current E10 of $-149.12. The current E10 is $-149.12. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Bio-Path Holdings (BPTH), the current E10 is $-149.12 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Bio-Path Holdings Business Description

Address No. 2407, 625 Stanwix Street, Pittsburgh, PA, USA, 15222
Bio-Path Holdings Inc is a clinical and preclinical stage oncology-focused RNAi nanoparticle drug development company. It is engaged in utilizing a novel technology that achieves systemic delivery for target-specific protein inhibition for any gene product that is over-expressed in disease. The company's drug candidate, prexigebersen, is in the efficacy portion of a Phase 2 clinical trial for acute myeloid leukemia (AML) in combination with low-dose cytarabine (LDAC) and combination with decitabine. The other drugs of the company are BP1002, BP1003, BP1001-A, and DNABILIZE.