ORYZF (Oryzon Genomics) E10: $-0.13 (As of Mar. 2026)


ORYZF Oryzon Genomics SA ORYZF
31 GF Score
Price $3.65
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What is Oryzon Genomics E10?

Oryzon Genomics ORYZF 31 E10 is $-0.13 as of Mar. 2026. GuruFocus rates ORYZF with a GF Score™ of 31/100.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Oryzon Genomics's adjusted earnings per share data for the three months ended in Mar. 2026 was $-0.020. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-0.13 for the trailing ten years ended in Mar. 2026.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

As of today (2026-06-25), Oryzon Genomics's current stock price is $3.645. Oryzon Genomics's E10 for the quarter that ended in Mar. 2026 was $-0.13. Oryzon Genomics's Shiller PE Ratio of today is .


Oryzon Genomics  (OTCPK:ORYZF) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Oryzon Genomics E10 Related Terms


Oryzon Genomics E10 Historical Data

* Premium members only.

The historical data trend for Oryzon Genomics's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Oryzon Genomics E10 Chart

Oryzon Genomics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 -0.12 -0.12

Oryzon Genomics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.10 0.00 -0.13 -0.12 -0.13

ORYZF vs VRTX, REGN, ALNY: E10 Comparison

For the Biotechnology subindustry, Oryzon Genomics's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Oryzon Genomics Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Oryzon Genomics's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Oryzon Genomics's Shiller PE Ratio falls into.


ORYZF
31GF Score
Oryzon Genomics SA ORYZF
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
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Oryzon Genomics E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Oryzon Genomics's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-0.02/128.4016*128.4016
=-0.020

Current CPI (Mar. 2026) = 128.4016.

Oryzon Genomics Quarterly Data

per share eps CPI Adj_EPS
201606 -0.083 100.333 -0.106
201609 -0.056 99.737 -0.072
201612 -0.039 101.842 -0.049
201703 -0.050 100.896 -0.064
201706 -0.052 101.848 -0.066
201709 -0.043 101.524 -0.054
201712 -0.050 102.975 -0.062
201803 -0.038 102.122 -0.048
201806 0.057 104.165 0.070
201809 -0.034 103.818 -0.042
201812 -0.022 104.193 -0.027
201903 -0.035 103.488 -0.043
201906 -0.016 104.612 -0.020
201909 -0.022 103.905 -0.027
201912 -0.025 105.015 -0.031
202003 -0.028 103.469 -0.035
202006 -0.005 104.254 -0.006
202009 -0.020 103.521 -0.025
202012 -0.029 104.456 -0.036
202103 -0.040 104.857 -0.049
202106 0.017 107.102 0.020
202109 -0.030 107.669 -0.036
202112 -0.043 111.298 -0.050
202203 -0.035 115.153 -0.039
202206 0.009 118.044 0.010
202209 -0.010 117.221 -0.011
202212 -0.047 117.650 -0.051
202303 -0.032 118.948 -0.035
202306 0.020 120.278 0.021
202309 -0.020 121.343 -0.021
202312 -0.033 121.300 -0.035
202403 -0.020 122.762 -0.021
202406 0.002 124.409 0.002
202409 -0.020 123.121 -0.021
202412 -0.042 124.753 -0.043
202503 -0.030 125.531 -0.031
202506 0.000 127.251 0.000
202509 0.010 126.842 0.010
202512 -0.015 128.402 -0.015
202603 -0.020 128.402 -0.020

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-0.13 mean?
Oryzon Genomics (ORYZF) has a E10 of $-0.13 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Oryzon Genomics and its competitors.
Is Oryzon Genomics' E10 too high?
Oryzon Genomics' current E10 is $-0.13. Overall, Oryzon Genomics has a GF Score™ of 31/100, reflecting its overall financial health beyond just this single metric.
How does Oryzon Genomics' E10 compare to VRTX and REGN?
Oryzon Genomics' E10 of $-0.13 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Oryzon Genomics and its competitors. Oryzon Genomics's current E10 is $-0.13. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Oryzon Genomics stock overvalued right now?
Oryzon Genomics (ORYZF) has a current E10 of $-0.13. The current E10 is $-0.13. Oryzon Genomics' overall GF Score™ is 31/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Oryzon Genomics (ORYZF), the current E10 is $-0.13 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Oryzon Genomics Business Description

Other Exchanges 0RDB:UKORY:SpainORN:Germany
Address Sant Ferran 74, Cornellà de Llobregat, Barcelona, ESP, 08940
Oryzon Genomics SA is a clinical stage biopharmaceutical company and engaged in the development of epigenetics-based therapeutics. It is engaged in the field of epigenetic medicine and in the development of therapeutic, biological solutions for cancer and neurodegenerative diseases.
31GF Score

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E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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