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Oryzon GenomicsORYZF 33 EV-to-EBITDA is -17.89 as of Jul. 17, 2026. GuruFocus rates ORYZF with a GF Score™ of 33/100. Among 398 Biotechnology companies, Oryzon Genomics ranks worse than 251256.03% on this metric.
EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Oryzon Genomics's enterprise value is $246.50 Mil.
Oryzon Genomics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $-13.78 Mil. Therefore, Oryzon Genomics's EV-to-EBITDA for today is -17.89.
The historical rank and industry rank for Oryzon Genomics's EV-to-EBITDA or its related term are showing as below:
ORYZF'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -42.75 Med: -20.29 Max: -8.43
Current: -18.13
During the past 12 years, the highest EV-to-EBITDA of Oryzon Genomics was -8.43. The lowest was -42.75. And the median was -20.29.
ORYZF's EV-to-EBITDA is ranked worse than 100% of 398
companies
in the Biotechnology industry
Industry Median: 12.29
vs ORYZF: -18.13
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Oryzon Genomics's PE Ratio (TTM) for today is calculated as:
Oryzon Genomics's share price for today is $3.655.
Oryzon Genomics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.025.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for Oryzon Genomics's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
ORYZF vs VRTX, REGN, ALNY: EV-to-EBITDA Comparison
For the Biotechnology subindustry, Oryzon Genomics's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Oryzon Genomics EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Oryzon Genomics's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Oryzon Genomics's EV-to-EBITDA falls into.
Oryzon Genomics's current Enterprise Value is $246.50 Mil.
Oryzon Genomics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-13.78 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Oryzon Genomics (ORYZF) has a EV-to-EBITDA of -17.89 as of Jul. 17, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Oryzon Genomics. According to the industry distribution chart, Oryzon Genomics ranks #999999 out of 398 companies in the Biotechnology industry.
Is Oryzon Genomics' EV-to-EBITDA too high?
Oryzon Genomics' current EV-to-EBITDA is -17.89. Based on the distribution chart, Oryzon Genomics ranks #999999 out of 398 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Oryzon Genomics has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Oryzon Genomics' EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Oryzon Genomics ranks #999999 out of 398 companies for EV-to-EBITDA. This places Oryzon Genomics in the lower half of its industry. The industry median EV-to-EBITDA is 12.29. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 12.29, based on 398 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Oryzon Genomics. For the Biotechnology industry, the median EV-to-EBITDA is 12.29 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Oryzon Genomics's current EV-to-EBITDA is -17.89. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Oryzon Genomics stock overvalued right now?
Oryzon Genomics (ORYZF) has a current EV-to-EBITDA of -17.89. The current EV-to-EBITDA is -17.89. Oryzon Genomics' overall GF Score™ is 33/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Oryzon Genomics (ORYZF), the current EV-to-EBITDA is -17.89 as of Jul. 17, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Oryzon Genomics SA is a clinical stage biopharmaceutical company and engaged in the development of epigenetics-based therapeutics. It is engaged in the field of epigenetic medicine and in the development of therapeutic, biological solutions for cancer and neurodegenerative diseases.
33GF Score
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