SHPH (Shuttle Pharmaceuticals Holdings) Earnings Yield (Joel Greenblatt) %: -370.37% (As of Mar. 2026)

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SHPH Shuttle Pharmaceuticals Holdings Inc SHPH
24 GF Score
Price $4.37
! 1 Warning Sign
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What is Shuttle Pharmaceuticals Holdings Earnings Yield (Joel Greenblatt) %?

Shuttle Pharmaceuticals Holdings SHPH -5.03% 24 Earnings Yield (Joel Greenblatt) % is -370.37% as of Mar. 2026. GuruFocus rates SHPH with a GF Score™ of 24/100. The stock has 1 warning sign investors should review. Among 1,010 Drug Manufacturers companies, Shuttle Pharmaceuticals Holdings ranks worse than 99.5% on this metric.

Shuttle Pharmaceuticals Holdings's Enterprise Value for the quarter that ended in Mar. 2026 was $2.89 Mil. Shuttle Pharmaceuticals Holdings's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-10.75 Mil. Shuttle Pharmaceuticals Holdings's Earnings Yield (Joel Greenblatt) for the quarter that ended in Mar. 2026 was -370.37%.

The historical rank and industry rank for Shuttle Pharmaceuticals Holdings's Earnings Yield (Joel Greenblatt) % or its related term are showing as below:

SHPH' s Earnings Yield (Joel Greenblatt) % Range Over the Past 10 Years
Min: -666.67   Med: 0   Max: 0
Current: -625

SHPH's Earnings Yield (Joel Greenblatt) % is ranked worse than
99.5% of 1010 companies
in the Drug Manufacturers industry
Industry Median: 3.25 vs SHPH: -625.00

Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.

A better indicator of the attractiveness of an investment which takes growth into account is the Forward Rate of Return (Yacktman) %. Shuttle Pharmaceuticals Holdings's Forward Rate of Return (Yacktman) % for the quarter that ended in Mar. 2026 was 0.00%. The Forward Rate of Return uses the normalized Free Cash Flow of the past five years, and considers growth. The forward rate of return can be thought of as the return that investors buying the stock today can expect from it in the future.


Shuttle Pharmaceuticals Holdings  (NAS:SHPH) Earnings Yield (Joel Greenblatt) % Explanation

Joel Greenblatt defines the earnings yield using the above equation because it more accurately reflects the company's profitability relative to its stock price. Items like interest payment and tax etc. are not directly related to the company's operational profitability.

Enterprise Value instead of market cap (share price) is used in the calculation because it is the real price stock and bond investors together pay for the company.


Be Aware

Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.

Forward Rate of Return (Yacktman) % based on Don Yacktman's definition is a better measure of the expected rate of return for a stock.


Shuttle Pharmaceuticals Holdings Earnings Yield (Joel Greenblatt) % Related Terms


Shuttle Pharmaceuticals Holdings Earnings Yield (Joel Greenblatt) % Historical Data

* Premium members only.

The historical data trend for Shuttle Pharmaceuticals Holdings's Earnings Yield (Joel Greenblatt) % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Shuttle Pharmaceuticals Holdings Earnings Yield (Joel Greenblatt) % Chart

Shuttle Pharmaceuticals Holdings Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Earnings Yield (Joel Greenblatt) %
Get a 7-Day Free Trial 0.00 -22.83 -136.99 -285.71 -333.33

Shuttle Pharmaceuticals Holdings Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Earnings Yield (Joel Greenblatt) % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1,111.11 10,000.00 -357.14 -333.33 -370.37

SHPH vs PLSH, SKYI, CPMD: Earnings Yield (Joel Greenblatt) % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Shuttle Pharmaceuticals Holdings's Earnings Yield (Joel Greenblatt) %, along with its competitors' market caps and Earnings Yield (Joel Greenblatt) % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Shuttle Pharmaceuticals Holdings Earnings Yield (Joel Greenblatt) % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Shuttle Pharmaceuticals Holdings's Earnings Yield (Joel Greenblatt) % distribution charts can be found below:

* The bar in red indicates where Shuttle Pharmaceuticals Holdings's Earnings Yield (Joel Greenblatt) % falls into.


SHPH
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Shuttle Pharmaceuticals Holdings Inc SHPH
Earnings Yield (Joel Greenblatt) % is just one metric. See GF Score™, valuation, warning signs, and more.
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Shuttle Pharmaceuticals Holdings Earnings Yield (Joel Greenblatt) % Calculation

In his book, The Little That Beat the Market, hedge fund manager Joel Greenblatt defines Earnings Yield as operating income divided by enterprise value.

Shuttle Pharmaceuticals Holdingss Earnings Yield (Joel Greenblatt) for the fiscal year that ended in Dec. 2025 is calculated as

Earnings Yield (Joel Greenblatt)=EBIT/Enterprise Value
=-11.651/3.534
=-329.68 %

Shuttle Pharmaceuticals Holdings's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-10.75 Mil.


What does a Earnings Yield (Joel Greenblatt) % of -370.37% mean?
Shuttle Pharmaceuticals Holdings (SHPH) has a Earnings Yield (Joel Greenblatt) % of -370.37% as of Mar. 2026. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Shuttle Pharmaceuticals Holdings and its competitors. According to the industry distribution chart, Shuttle Pharmaceuticals Holdings ranks #1005 out of 1010 companies in the Drug Manufacturers industry, placing it in the top 99.5%.
Is Shuttle Pharmaceuticals Holdings' Earnings Yield (Joel Greenblatt) % too high?
Shuttle Pharmaceuticals Holdings' current Earnings Yield (Joel Greenblatt) % is -370.37%. Based on the distribution chart, Shuttle Pharmaceuticals Holdings ranks #1005 out of 1010 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Shuttle Pharmaceuticals Holdings has a GF Score™ of 24/100, reflecting its overall financial health beyond just this single metric.
How does Shuttle Pharmaceuticals Holdings' Earnings Yield (Joel Greenblatt) % compare to PLSH and SKYI?
According to the Drug Manufacturers industry distribution chart, Shuttle Pharmaceuticals Holdings ranks #1005 out of 1010 companies for Earnings Yield (Joel Greenblatt) %. This places Shuttle Pharmaceuticals Holdings in the lower half of its industry. The industry median Earnings Yield (Joel Greenblatt) % is 3.25. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Earnings Yield (Joel Greenblatt) % for a Drug Manufacturers company?
The median Earnings Yield (Joel Greenblatt) % among Drug Manufacturers companies is 3.25, based on 1,010 companies in the industry. Companies in the top quartile (top 25%) have a Earnings Yield (Joel Greenblatt) % significantly above this median, while those in the bottom quartile fall well below. However, Earnings Yield (Joel Greenblatt) % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Earnings Yield (Joel Greenblatt) % mean?
A high Earnings Yield (Joel Greenblatt) % can signal that a stock is expensive relative to its fundamentals. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Shuttle Pharmaceuticals Holdings and its competitors. For the Drug Manufacturers industry, the median Earnings Yield (Joel Greenblatt) % is 3.25 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Shuttle Pharmaceuticals Holdings's current Earnings Yield (Joel Greenblatt) % is -370.37%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Shuttle Pharmaceuticals Holdings stock overvalued right now?
Shuttle Pharmaceuticals Holdings (SHPH) has a current Earnings Yield (Joel Greenblatt) % of -370.37%. The current Earnings Yield (Joel Greenblatt) % is -370.37%. Shuttle Pharmaceuticals Holdings' overall GF Score™ is 24/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Earnings Yield (Joel Greenblatt) % calculated?
Earnings Yield (Joel Greenblatt) % is calculated from a company's financial statements. For Shuttle Pharmaceuticals Holdings (SHPH), the current Earnings Yield (Joel Greenblatt) % is -370.37% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Shuttle Pharmaceuticals Holdings Business Description

Address 401 Professional Drive, Suite 260, Gaithersburg, MD, USA, 20879
Shuttle Pharmaceuticals Holdings Inc is a clinical-stage pharmaceutical company leveraging its proprietary technology to develop novel therapies designed to cure cancers. The company has one operating segment with a focus on the development of novel drug therapies, including cancer therapies, extending new applications of radiation therapy, and other drug development, including through the use of the Molecule.ai platform by the company as well as licensing the right to use Molecuile.ai to others. The company's goal is to extend the benefits of cancer treatments with surgery, radiation therapy, chemotherapy and immunotherapy. Radiation therapy (RT) is one of the effective modalities for treating cancers. Its pipeline includes: Ropidoxuridine, HDAC Inhibitors, PSMA-B, and PC-Rad Test.
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