SHPH (Shuttle Pharmaceuticals Holdings) OCF Yield %: -402.40 (As of Jun. 28, 2026)


SHPH Shuttle Pharmaceuticals Holdings Inc SHPH
24 GF Score
Price $3.98
! 1 Warning Sign
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What is Shuttle Pharmaceuticals Holdings OCF Yield %?

Shuttle Pharmaceuticals Holdings SHPH +6.35% 24 OCF Yield % is -402.40 as of Jun. 28, 2026. GuruFocus rates SHPH with a GF Score™ of 24/100. The stock has 1 warning sign investors should review. Among 1,002 Drug Manufacturers companies, Shuttle Pharmaceuticals Holdings ranks worse than 99.5% on this metric.

OCF Yield % is calculated as Cash Flow from Operations divided by Market Capitalization. It is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

As of today, Shuttle Pharmaceuticals Holdings's Trailing 12-Month Cash Flow from Operations is $-9.37 Mil, and Market Cap is $2.33 Mil. Therefore, Shuttle Pharmaceuticals Holdings's OCF Yield % for today is -402.40%.

The historical rank and industry rank for Shuttle Pharmaceuticals Holdings's OCF Yield % or its related term are showing as below:

SHPH' s OCF Yield % Range Over the Past 10 Years
Min: -402.4   Med: 0   Max: -402.4
Current: -402.4


During the past 6 years, the highest OCF Yield % of Shuttle Pharmaceuticals Holdings was -402.40%. The lowest was -402.40%. And the median was %.

SHPH's OCF Yield % is ranked worse than
99.5% of 1002 companies
in the Drug Manufacturers industry
Industry Median: 3.61 vs SHPH: -402.40

Shuttle Pharmaceuticals Holdings's OCF Margin % for the quarter that ended in Mar. 2026 was %.


Shuttle Pharmaceuticals Holdings OCF Yield % Explanation

Similar to Earnings Yield %, OCF Yield % is financial solvency ratio. A lower ratio suggests a less attractive investment, indicating that investors might not receive substantial returns in proportion to their investment. Conversely, a high operating cash flow yield signals that a company generates sufficient cash to comfortably meet its debts, obligations, and dividend payments, making it a promising investment choice.


Shuttle Pharmaceuticals Holdings OCF Yield % Related Terms


Shuttle Pharmaceuticals Holdings OCF Yield % Historical Data

* Premium members only.

The historical data trend for Shuttle Pharmaceuticals Holdings's OCF Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Shuttle Pharmaceuticals Holdings OCF Yield % Chart

Shuttle Pharmaceuticals Holdings Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Yield %
Get a 7-Day Free Trial 0.00 -9.72 -76.66 -213.24 -260.78

Shuttle Pharmaceuticals Holdings Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
OCF Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -399.76 -333.12 -238.71 -107.04 -256.63

SHPH vs PRFX, CBIH, UPC: OCF Yield % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Shuttle Pharmaceuticals Holdings's OCF Yield %, along with its competitors' market caps and OCF Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Shuttle Pharmaceuticals Holdings OCF Yield % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Shuttle Pharmaceuticals Holdings's OCF Yield % distribution charts can be found below:

* The bar in red indicates where Shuttle Pharmaceuticals Holdings's OCF Yield % falls into.


SHPH
24GF Score
Shuttle Pharmaceuticals Holdings Inc SHPH
OCF Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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Shuttle Pharmaceuticals Holdings OCF Yield % Calculation

OCF Yield % is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

Shuttle Pharmaceuticals Holdings's OCF Yield % for the fiscal year that ended in Dec. 2025 is calculated as

OCF Yield %=Cash Flow from Operations / Market Cap
=-9.482 / 3.636
=-260.78%

Shuttle Pharmaceuticals Holdings's annualized OCF Yield % for the quarter that ended in Mar. 2026 is calculated as

OCF Yield %=Cash Flow from Operations * Annualized Factor / Market Cap
=-2.417 * 4 / 3.76734
=-256.63%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Yield % →
What does a OCF Yield % of -402.40 mean?
Shuttle Pharmaceuticals Holdings (SHPH) has a OCF Yield % of -402.40 as of Jun. 28, 2026. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Shuttle Pharmaceuticals Holdings and its competitors. According to the industry distribution chart, Shuttle Pharmaceuticals Holdings ranks #997 out of 1002 companies in the Drug Manufacturers industry, placing it in the top 99.5%.
Is Shuttle Pharmaceuticals Holdings' OCF Yield % too high?
Shuttle Pharmaceuticals Holdings' current OCF Yield % is -402.40. Based on the distribution chart, Shuttle Pharmaceuticals Holdings ranks #997 out of 1002 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Shuttle Pharmaceuticals Holdings has a GF Score™ of 24/100, reflecting its overall financial health beyond just this single metric.
How does Shuttle Pharmaceuticals Holdings' OCF Yield % compare to PRFX and CBIH?
According to the Drug Manufacturers industry distribution chart, Shuttle Pharmaceuticals Holdings ranks #997 out of 1002 companies for OCF Yield %. This places Shuttle Pharmaceuticals Holdings in the lower half of its industry. The industry median OCF Yield % is 3.61. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Yield % for a Drug Manufacturers company?
The median OCF Yield % among Drug Manufacturers companies is 3.61, based on 1,002 companies in the industry. Companies in the top quartile (top 25%) have a OCF Yield % significantly above this median, while those in the bottom quartile fall well below. However, OCF Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Yield % mean?
A high OCF Yield % can signal that a stock is expensive relative to its fundamentals. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Shuttle Pharmaceuticals Holdings and its competitors. For the Drug Manufacturers industry, the median OCF Yield % is 3.61 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Shuttle Pharmaceuticals Holdings's current OCF Yield % is -402.40. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Shuttle Pharmaceuticals Holdings stock overvalued right now?
Shuttle Pharmaceuticals Holdings (SHPH) has a current OCF Yield % of -402.40. The current OCF Yield % is -402.40. Shuttle Pharmaceuticals Holdings' overall GF Score™ is 24/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Yield % calculated?
OCF Yield % is calculated from a company's financial statements. For Shuttle Pharmaceuticals Holdings (SHPH), the current OCF Yield % is -402.40 as of Jun. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Shuttle Pharmaceuticals Holdings Business Description

Address 401 Professional Drive, Suite 260, Gaithersburg, MD, USA, 20879
Shuttle Pharmaceuticals Holdings Inc is a clinical-stage pharmaceutical company leveraging its proprietary technology to develop novel therapies designed to cure cancers. The company has one operating segment with a focus on the development of novel drug therapies, including cancer therapies, extending new applications of radiation therapy, and other drug development, including through the use of the Molecule.ai platform by the company as well as licensing the right to use Molecuile.ai to others. The company's goal is to extend the benefits of cancer treatments with surgery, radiation therapy, chemotherapy and immunotherapy. Radiation therapy (RT) is one of the effective modalities for treating cancers. Its pipeline includes: Ropidoxuridine, HDAC Inhibitors, PSMA-B, and PC-Rad Test.
24GF Score

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