CRNX (Crinetics Pharmaceuticals) EBITDA Margin %: -1,296.98% (As of Mar. 2026)


CRNX Crinetics Pharmaceuticals Inc CRNX
47 GF Score
Price $36.91
GF Value $678.51
Valuation Possible Value Trap
! 5 Warning Signs
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What is Crinetics Pharmaceuticals EBITDA Margin %?

Crinetics Pharmaceuticals CRNX +0.82% 47 EBITDA Margin % is -1,296.98% as of Mar. 2026. GuruFocus rates CRNX with a GF Score™ of 47/100 and a GF Value™ of $678.51 (Possible Value Trap). The stock has 5 warning signs investors should review. Among 942 Biotechnology companies, Crinetics Pharmaceuticals ranks worse than 86.73% on this metric.

EBITDA Margin % is calculated as EBITDA divided by its Revenue. Crinetics Pharmaceuticals's EBITDA for the three months ended in Mar. 2026 was $-139.22 Mil. Crinetics Pharmaceuticals's Revenue for the three months ended in Mar. 2026 was $10.73 Mil. Therefore, Crinetics Pharmaceuticals's EBITDA margin for the quarter that ended in Mar. 2026 was -1,296.98%.


Crinetics Pharmaceuticals  (NAS:CRNX) EBITDA Margin % Explanation

EBITDA Margin % is the ratio of EBITDA divided by net sales or Revenue. It is an performance metric measuring company's operating profitability. EBITDA Margin takes depreciation and amortization, interest expense and tax into account, which makes it easy to compare the relative profitability of companies of different sizes in the same industry.


Crinetics Pharmaceuticals EBITDA Margin % Related Terms


Crinetics Pharmaceuticals EBITDA Margin % Historical Data

* Premium members only.

The historical data trend for Crinetics Pharmaceuticals's EBITDA Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Crinetics Pharmaceuticals EBITDA Margin % Chart

Crinetics Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBITDA Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -9,905.38 -3,523.31 -5,519.81 -32,345.43 -6,664.23

Crinetics Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EBITDA Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -30,603.88 -12,429.97 -99,002.80 -2,153.42 -1,296.98

CRNX vs CPRX, NAMS, RCUS: EBITDA Margin % Comparison

For the Biotechnology subindustry, Crinetics Pharmaceuticals's EBITDA Margin %, along with its competitors' market caps and EBITDA Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Crinetics Pharmaceuticals EBITDA Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Crinetics Pharmaceuticals's EBITDA Margin % distribution charts can be found below:

* The bar in red indicates where Crinetics Pharmaceuticals's EBITDA Margin % falls into.


CRNX
47GF Score
Crinetics Pharmaceuticals Inc CRNX
EBITDA Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Crinetics Pharmaceuticals EBITDA Margin % Calculation

EBITDA margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent.

Crinetics Pharmaceuticals's EBITDA Margin % for the fiscal year that ended in Dec. 2025 is calculated as

EBITDA Margin %=EBITDA (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-512.879/7.696
=-6,664.23 %

Crinetics Pharmaceuticals's EBITDA Margin % for the quarter that ended in Mar. 2026 is calculated as

EBITDA Margin %=EBITDA (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-139.218/10.734
=-1,296.98 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBITDA Margin % →
What does a EBITDA Margin % of -1,296.98% mean?
Crinetics Pharmaceuticals (CRNX) has a EBITDA Margin % of -1,296.98% as of Mar. 2026. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Crinetics Pharmaceuticals and its competitors. According to the industry distribution chart, Crinetics Pharmaceuticals ranks #817 out of 942 companies in the Biotechnology industry, placing it in the top 86.7%.
Is Crinetics Pharmaceuticals' EBITDA Margin % too high?
Crinetics Pharmaceuticals' current EBITDA Margin % is -1,296.98%. Based on the distribution chart, Crinetics Pharmaceuticals ranks #817 out of 942 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Crinetics Pharmaceuticals has a GF Score™ of 47/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Crinetics Pharmaceuticals' EBITDA Margin % compare to CPRX and NAMS?
According to the Biotechnology industry distribution chart, Crinetics Pharmaceuticals ranks #817 out of 942 companies for EBITDA Margin %. This places Crinetics Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA Margin % for a Biotechnology company?
A good EBITDA Margin % depends on the Biotechnology industry context. However, EBITDA Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA Margin % mean?
A high EBITDA Margin % can signal that a stock is expensive relative to its fundamentals. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Crinetics Pharmaceuticals and its competitors. Crinetics Pharmaceuticals's current EBITDA Margin % is -1,296.98%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Crinetics Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Crinetics Pharmaceuticals (CRNX) is currently considered Possible Value Trap. The stock's GF Value™ is $678.51, compared to a current price of $36.91 — trading 94.6% below its estimated fair value. The current EBITDA Margin % is -1,296.98%. Crinetics Pharmaceuticals' overall GF Score™ is 47/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA Margin % calculated?
EBITDA Margin % is calculated from a company's financial statements. For Crinetics Pharmaceuticals (CRNX), the current EBITDA Margin % is -1,296.98% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Crinetics Pharmaceuticals (CRNX) Overvalued in 2026?

Based on GuruFocus' analysis, Crinetics Pharmaceuticals stock appears to be undervalued. The current stock price of $36.91 is trading 94.6% below its estimated GF Value™ of $678.51. GuruFocus considers Crinetics Pharmaceuticals to be Possible Value Trap.

Key valuation signals for CRNX:

  • EBITDA Margin %: -1,296.98%
  • GF Value™: $678.51 vs. price of $36.91 (94.6% below fair value)
  • GF Score™: 47/100 with 5 warning signs

No single metric tells the full story. See the CRNX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Crinetics Pharmaceuticals Business Description

Other Exchanges 6Z4:Germany
Address 6055 Lusk Boulevard, San Diego, CA, USA, 92121
Crinetics Pharmaceuticals Inc is a commercial-stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. Its main product, Palsonify (paltusotine), is a once-daily, oral treatment approved by the FDA for adults with acromegaly who have had an inadequate response to surgery and/or for whom surgery is not an option. Additionally, the company's development pipeline includes several programs, including a late-stage investigational candidate, atumelnant, currently in development for CAH and ADCS, and CRN09682, a NDC candidate that is being developed to treat SST2-expressing NETs and other SST2-expressing solid tumors.
47GF Score

Get the complete analysis for CRNX

EBITDA Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$36.91
Price
$678.51
GF Value