CRNX (Crinetics Pharmaceuticals) ROA %: -40.46% (As of Mar. 2026)


CRNX Crinetics Pharmaceuticals Inc CRNX
47 GF Score
Price $41.29
GF Value $699.74
Valuation Possible Value Trap
! 5 Warning Signs
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What is Crinetics Pharmaceuticals ROA %?

Crinetics Pharmaceuticals CRNX +6.79% 47 ROA % is -40.46% as of Mar. 2026. GuruFocus rates CRNX with a GF Score™ of 47/100 and a GF Value™ of $699.74 (Possible Value Trap). The stock has 5 warning signs investors should review. Among 1,418 Biotechnology companies, Crinetics Pharmaceuticals ranks worse than 55.08% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Crinetics Pharmaceuticals's annualized Net Income for the quarter that ended in Mar. 2026 was $-511.38 Mil. Crinetics Pharmaceuticals's average Total Assets over the quarter that ended in Mar. 2026 was $1,263.79 Mil. Therefore, Crinetics Pharmaceuticals's annualized ROA % for the quarter that ended in Mar. 2026 was -40.46%.

The historical rank and industry rank for Crinetics Pharmaceuticals's ROA % or its related term are showing as below:

CRNX' s ROA % Range Over the Past 10 Years
Min: -64.95   Med: -41.87   Max: -28.83
Current: -38.94

During the past 10 years, Crinetics Pharmaceuticals's highest ROA % was -28.83%. The lowest was -64.95%. And the median was -41.87%.

CRNX's ROA % is ranked worse than
55.08% of 1418 companies
in the Biotechnology industry
Industry Median: -32.87 vs CRNX: -38.94

Crinetics Pharmaceuticals  (NAS:CRNX) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=-511.38/1263.79
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-511.38 / 42.936)*(42.936 / 1263.79)
=Net Margin %*Asset Turnover
=-1191.03 %*0.034
=-40.46 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Crinetics Pharmaceuticals ROA % Related Terms


Crinetics Pharmaceuticals ROA % Historical Data

* Premium members only.

The historical data trend for Crinetics Pharmaceuticals's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Crinetics Pharmaceuticals ROA % Chart

Crinetics Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -40.28 -46.62 -43.45 -28.83 -36.34

Crinetics Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -27.69 -34.90 -41.87 -42.31 -40.46

CRNX vs CPRX, NAMS, RCUS: ROA % Comparison

For the Biotechnology subindustry, Crinetics Pharmaceuticals's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Crinetics Pharmaceuticals ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Crinetics Pharmaceuticals's ROA % distribution charts can be found below:

* The bar in red indicates where Crinetics Pharmaceuticals's ROA % falls into.


CRNX
47GF Score
Crinetics Pharmaceuticals Inc CRNX
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
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Crinetics Pharmaceuticals ROA % Calculation

Crinetics Pharmaceuticals's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-465.317/( (1434.592+1126.257)/ 2 )
=-465.317/1280.4245
=-36.34 %

Crinetics Pharmaceuticals's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=-511.38/( (1126.257+1401.323)/ 2 )
=-511.38/1263.79
=-40.46 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -40.46% mean?
Crinetics Pharmaceuticals (CRNX) has a ROA % of -40.46% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Crinetics Pharmaceuticals and its competitors. According to the industry distribution chart, Crinetics Pharmaceuticals ranks #781 out of 1418 companies in the Biotechnology industry, placing it in the top 55.1%.
Is Crinetics Pharmaceuticals' ROA % too high?
Crinetics Pharmaceuticals' current ROA % is -40.46%. Based on the distribution chart, Crinetics Pharmaceuticals ranks #781 out of 1418 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Crinetics Pharmaceuticals has a GF Score™ of 47/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Crinetics Pharmaceuticals' ROA % compare to CPRX and NAMS?
According to the Biotechnology industry distribution chart, Crinetics Pharmaceuticals ranks #781 out of 1418 companies for ROA %. This places Crinetics Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Crinetics Pharmaceuticals and its competitors. Crinetics Pharmaceuticals's current ROA % is -40.46%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Crinetics Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Crinetics Pharmaceuticals (CRNX) is currently considered Possible Value Trap. The stock's GF Value™ is $699.74, compared to a current price of $41.29 — trading 94.1% below its estimated fair value. The current ROA % is -40.46%. Crinetics Pharmaceuticals' overall GF Score™ is 47/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Crinetics Pharmaceuticals (CRNX), the current ROA % is -40.46% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Crinetics Pharmaceuticals (CRNX) Overvalued in 2026?

Based on GuruFocus' analysis, Crinetics Pharmaceuticals stock appears to be undervalued. The current stock price of $41.29 is trading 94.1% below its estimated GF Value™ of $699.74. GuruFocus considers Crinetics Pharmaceuticals to be Possible Value Trap.

Key valuation signals for CRNX:

  • ROA %: -40.46%
  • GF Value™: $699.74 vs. price of $41.29 (94.1% below fair value)
  • GF Score™: 47/100 with 5 warning signs

No single metric tells the full story. See the CRNX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Crinetics Pharmaceuticals Business Description

Other Exchanges 6Z4:Germany
Address 6055 Lusk Boulevard, San Diego, CA, USA, 92121
Crinetics Pharmaceuticals Inc is a commercial-stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. Its main product, Palsonify (paltusotine), is a once-daily, oral treatment approved by the FDA for adults with acromegaly who have had an inadequate response to surgery and/or for whom surgery is not an option. Additionally, the company's development pipeline includes several programs, including a late-stage investigational candidate, atumelnant, currently in development for CAH and ADCS, and CRN09682, a NDC candidate that is being developed to treat SST2-expressing NETs and other SST2-expressing solid tumors.
47GF Score

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ROA % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$41.29
Price
$699.74
GF Value