PersonalisPSNL +10.59%59 EBITDA Margin % is -178.37% as of Mar. 2026. GuruFocus rates PSNL with a GF Score™ of 59/100 and a GF Value™ of $2.07 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 204 Medical Diagnostics & Research companies, Personalis ranks worse than 82.84% on this metric.
EBITDA Margin % is calculated as EBITDA divided by its Revenue. Personalis's EBITDA for the
three
months ended in Mar. 2026 was $-27.60 Mil. Personalis's Revenue for the
three
months ended in Mar. 2026 was $15.47 Mil. Therefore, Personalis's EBITDA margin for the quarter that ended in Mar. 2026 was -178.37%.
Personalis (NAS:PSNL) EBITDA Margin % Explanation
EBITDA Margin % is the ratio of EBITDA divided by net sales or Revenue. It is an performance metric measuring company's operating profitability. EBITDA Margin takes depreciation and amortization, interest expense and tax into account, which makes it easy to compare the relative profitability of companies of different sizes in the same industry.
Personalis EBITDA Margin % Related Terms
Personalis EBITDA Margin % Historical Data
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The historical data trend for Personalis's EBITDA Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
PSNL vs CDNA, OPK, NEO: EBITDA Margin % Comparison
For the Diagnostics & Research subindustry, Personalis's EBITDA Margin %, along with its competitors' market caps and EBITDA Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Personalis EBITDA Margin % vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, Personalis's EBITDA Margin % distribution charts can be found below:
* The bar in red indicates where Personalis's EBITDA Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Personalis (PSNL) has a EBITDA Margin % of -178.37% as of Mar. 2026. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Personalis and its competitors. According to the industry distribution chart, Personalis ranks #169 out of 204 companies in the Medical Diagnostics & Research industry, placing it in the top 82.8%.
Is Personalis' EBITDA Margin % too high?
Personalis' current EBITDA Margin % is -178.37%. Based on the distribution chart, Personalis ranks #169 out of 204 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, Personalis has a GF Score™ of 59/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Personalis' EBITDA Margin % compare to CDNA and OPK?
According to the Medical Diagnostics & Research industry distribution chart, Personalis ranks #169 out of 204 companies for EBITDA Margin %. This places Personalis in the lower half of its industry. The industry median EBITDA Margin % is 5.20. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA Margin % for a Medical Diagnostics & Research company?
The median EBITDA Margin % among Medical Diagnostics & Research companies is 5.20, based on 204 companies in the industry. Companies in the top quartile (top 25%) have a EBITDA Margin % significantly above this median, while those in the bottom quartile fall well below. However, EBITDA Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA Margin % mean?
A high EBITDA Margin % can signal that a stock is expensive relative to its fundamentals. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Personalis and its competitors. For the Medical Diagnostics & Research industry, the median EBITDA Margin % is 5.20 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Personalis's current EBITDA Margin % is -178.37%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Personalis stock overvalued right now?
Based on GuruFocus' analysis, Personalis (PSNL) is currently considered Significantly Overvalued. The stock's GF Value™ is $2.07, compared to a current price of $11.13 — trading 437.4% above its estimated fair value. The current EBITDA Margin % is -178.37%. Personalis' overall GF Score™ is 59/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA Margin % calculated?
EBITDA Margin % is calculated from a company's financial statements. For Personalis (PSNL), the current EBITDA Margin % is -178.37% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Personalis (PSNL) Overvalued in 2026?
Based on GuruFocus' analysis, Personalis stock appears to be overvalued.
The current stock price of $11.13 is trading 437.4% above its estimated GF Value™ of $2.07.
GuruFocus considers Personalis to be Significantly Overvalued.
Key valuation signals for PSNL:
EBITDA Margin %: -178.37%
GF Value™: $2.07 vs. price of $11.13 (437.4% above fair value)
No single metric tells the full story. See the PSNL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Personalis Inc is a provider of genomic sequencing and analytics solutions to support the development of personalized cancer vaccines and other next-generation cancer immunotherapies. It has one segment, the sale of sequencing and data analysis services. The company' products include ImmunoID NeXT, NeXT Personal, NeXT Dx Test, and other pharma research solutions.
59GF Score
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