PersonalisPSNL +12.92%59 Net Margin % is -194.11% as of Mar. 2026. GuruFocus rates PSNL with a GF Score™ of 59/100 and a GF Value™ of $2.07 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 204 Medical Diagnostics & Research companies, Personalis ranks worse than 82.84% on this metric.
Net margin is calculated as Net Income divided by its Revenue. Personalis's Net Income for the
three
months ended in Mar. 2026 was $-30.03 Mil. Personalis's Revenue for the
three
months ended in Mar. 2026 was $15.47 Mil. Therefore, Personalis's net margin for the quarter that ended in Mar. 2026 was -194.11%.
The historical rank and industry rank for Personalis's Net Margin % or its related term are showing as below:
PSNL'
s Net Margin % Range Over the Past 10 Years
Min: -251.23 Med: -96.06 Max: -38.47
Current: -148.11
PSNL's Net Margin % is ranked worse than 82.84% of 204
companies
in the Medical Diagnostics & Research industry
Industry Median: -2.405
vs PSNL: -148.11
Personalis (NAS:PSNL) Net Margin % Explanation
Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.
But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.
Personalis Net Margin % Related Terms
Personalis Net Margin % Historical Data
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The historical data trend for Personalis's Net Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Diagnostics & Research subindustry, Personalis's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Personalis Net Margin % vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, Personalis's Net Margin % distribution charts can be found below:
* The bar in red indicates where Personalis's Net Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Personalis (PSNL) has a Net Margin % of -194.11% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Personalis and its competitors. According to the industry distribution chart, Personalis ranks #169 out of 204 companies in the Medical Diagnostics & Research industry, placing it in the top 82.8%.
Is Personalis' Net Margin % too high?
Personalis' current Net Margin % is -194.11%. Based on the distribution chart, Personalis ranks #169 out of 204 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, Personalis has a GF Score™ of 59/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Personalis' Net Margin % compare to CDNA and OPK?
According to the Medical Diagnostics & Research industry distribution chart, Personalis ranks #169 out of 204 companies for Net Margin %. This places Personalis in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Medical Diagnostics & Research company?
A good Net Margin % depends on the Medical Diagnostics & Research industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Personalis and its competitors. Personalis's current Net Margin % is -194.11%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Personalis stock overvalued right now?
Based on GuruFocus' analysis, Personalis (PSNL) is currently considered Significantly Overvalued. The stock's GF Value™ is $2.07, compared to a current price of $11.36 — trading 448.8% above its estimated fair value. The current Net Margin % is -194.11%. Personalis' overall GF Score™ is 59/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Personalis (PSNL), the current Net Margin % is -194.11% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Personalis (PSNL) Overvalued in 2026?
Based on GuruFocus' analysis, Personalis stock appears to be overvalued.
The current stock price of $11.36 is trading 448.8% above its estimated GF Value™ of $2.07.
GuruFocus considers Personalis to be Significantly Overvalued.
Key valuation signals for PSNL:
Net Margin %: -194.11%
GF Value™: $2.07 vs. price of $11.36 (448.8% above fair value)
No single metric tells the full story. See the PSNL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Personalis Inc is a provider of genomic sequencing and analytics solutions to support the development of personalized cancer vaccines and other next-generation cancer immunotherapies. It has one segment, the sale of sequencing and data analysis services. The company' products include ImmunoID NeXT, NeXT Personal, NeXT Dx Test, and other pharma research solutions.
59GF Score
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Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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