Ionis Pharmaceuticals (MIL:1IONS) Effective Interest Rate on Debt %: 3.73% (As of Jun. 2026)

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MIL:1IONS Ionis Pharmaceuticals Inc MIL:1IONS
48 GF Score
Price €48.44
GF Value €44.73
Valuation Modestly Overvalued
! 5 Warning Signs
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What is Ionis Pharmaceuticals Effective Interest Rate on Debt %?

Ionis Pharmaceuticals MIL:1IONS 48 Effective Interest Rate on Debt % is 3.73% as of Jun. 2026. GuruFocus rates MIL:1IONS with a GF Score™ of 48/100 and a GF Value™ of €44.73 (Modestly Overvalued). The stock has 5 warning signs investors should review.

Effective Interest Rate on Debt % is the usage rate that a borrower actually pays on a debt. It is calculated as the positive value of Interest Expense divided by its average total debt. Total debt equals to Long-Term Debt & Capital Lease Obligation plus Short-Term Debt & Capital Lease Obligation. Ionis Pharmaceuticals's annualized positive value of Interest Expense for the quarter that ended in Jun. 2026 was €71.2 Mil. Ionis Pharmaceuticals's average total debt for the quarter that ended in Jun. 2026 was €1,909.8 Mil. Therefore, Ionis Pharmaceuticals's annualized Effective Interest Rate on Debt % for the quarter that ended in Jun. 2026 was 3.73%.


Ionis Pharmaceuticals  (MIL:1IONS) Effective Interest Rate on Debt % Explanation

Effective Interest Rate on Debt % measures the usage rate that a borrower actually pays on a debt.


Ionis Pharmaceuticals Effective Interest Rate on Debt % Related Terms


Ionis Pharmaceuticals Effective Interest Rate on Debt % Historical Data

* Premium members only.

The historical data trend for Ionis Pharmaceuticals's Effective Interest Rate on Debt % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ionis Pharmaceuticals Effective Interest Rate on Debt % Chart

Ionis Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Effective Interest Rate on Debt %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.42 0.64 5.69 6.00 4.62

Ionis Pharmaceuticals Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Effective Interest Rate on Debt % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 5.81 5.60 4.75 3.99 3.73

MIL:1IONS vs KYMR, PRAX, HALO: Effective Interest Rate on Debt % Comparison

For the Biotechnology subindustry, Ionis Pharmaceuticals's Effective Interest Rate on Debt %, along with its competitors' market caps and Effective Interest Rate on Debt % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ionis Pharmaceuticals Effective Interest Rate on Debt % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ionis Pharmaceuticals's Effective Interest Rate on Debt % distribution charts can be found below:

* The bar in red indicates where Ionis Pharmaceuticals's Effective Interest Rate on Debt % falls into.


MIL:1IONS
48GF Score
Ionis Pharmaceuticals Inc MIL:1IONS
Effective Interest Rate on Debt % is just one metric. See GF Score™, valuation, warning signs, and more.
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Ionis Pharmaceuticals Effective Interest Rate on Debt % Calculation

Ionis Pharmaceuticals's annualized Effective Interest Rate on Debt % for the fiscal year that ended in Dec. 2025 is calculated as

Effective Interest Rate on Debt %
=-1  *  Interest Expense/( (Total Debt  (A: Dec. 2024 )+Total Debt  (A: Dec. 2025 ))/ count )
=-1  *  -71.977/( (1352.823+1763.093)/ 2 )
=-1  *  -71.977/1557.958
=4.62 %

where

Total Debt  (A: Dec. 2024 )
=Long-Term Debt & Capital Lease Obligation + Short-Term Debt & Capital Lease Obligation
=1343.962 + 8.861
=1352.823

Total Debt  (A: Dec. 2025 )
=Long-Term Debt & Capital Lease Obligation + Short-Term Debt & Capital Lease Obligation
=1374.791 + 388.302
=1763.093

Ionis Pharmaceuticals's annualized Effective Interest Rate on Debt % for the quarter that ended in Jun. 2026 is calculated as

Effective Interest Rate on Debt %
=-1  *  Interest Expense/( (Total Debt  (Q: Mar. 2026 )+Total Debt  (Q: Jun. 2026 ))/ count )
=-1  *  -71.196/( (1765.425+2054.141)/ 2 )
=-1  *  -71.196/1909.783
=3.73 %

where

Total Debt  (Q: Mar. 2026 )
=Long-Term Debt & Capital Lease Obligation + Short-Term Debt & Capital Lease Obligation
=1391.313 + 374.112
=1765.425

Total Debt  (Q: Jun. 2026 )
=Long-Term Debt & Capital Lease Obligation + Short-Term Debt & Capital Lease Obligation
=1400.537 + 653.604
=2054.141

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Effective Interest Rate on Debt %, the Interest Expense of the last fiscal year and the average total debt over the fiscal year are used. In calculating the quarterly data, the Interest Expense data used here is four times the quarterly (Jun. 2026) interest expense data. Effective Interest Rate on Debt % is displayed in the 30-year financial page.

What does a Effective Interest Rate on Debt % of 3.73% mean?
Ionis Pharmaceuticals (MIL:1IONS) has a Effective Interest Rate on Debt % of 3.73% as of Jun. 2026. Effective interest rate on debt is the rate a company actually pays on its debt. View historical data on Ionis Pharmaceuticals and its competitors.
Is Ionis Pharmaceuticals' Effective Interest Rate on Debt % too high?
Ionis Pharmaceuticals' current Effective Interest Rate on Debt % is 3.73%. Overall, Ionis Pharmaceuticals has a GF Score™ of 48/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Ionis Pharmaceuticals' Effective Interest Rate on Debt % compare to KYMR and PRAX?
Ionis Pharmaceuticals' Effective Interest Rate on Debt % of 3.73% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Effective Interest Rate on Debt % for a Biotechnology company?
A good Effective Interest Rate on Debt % depends on the Biotechnology industry context. However, Effective Interest Rate on Debt % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Effective Interest Rate on Debt % mean?
A high Effective Interest Rate on Debt % can signal that a stock is expensive relative to its fundamentals. Effective interest rate on debt is the rate a company actually pays on its debt. View historical data on Ionis Pharmaceuticals and its competitors. Ionis Pharmaceuticals's current Effective Interest Rate on Debt % is 3.73%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ionis Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Ionis Pharmaceuticals (MIL:1IONS) is currently considered Modestly Overvalued. The stock's GF Value™ is €44.73, compared to a current price of €48.44 — trading 8.3% above its estimated fair value. The current Effective Interest Rate on Debt % is 3.73%. Ionis Pharmaceuticals' overall GF Score™ is 48/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Effective Interest Rate on Debt % calculated?
Effective Interest Rate on Debt % is calculated from a company's financial statements. For Ionis Pharmaceuticals (MIL:1IONS), the current Effective Interest Rate on Debt % is 3.73% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ionis Pharmaceuticals (MIL:1IONS) Overvalued in 2026?

Based on GuruFocus' analysis, Ionis Pharmaceuticals stock appears to be overvalued. The current stock price of €48.44 is trading 8.3% above its estimated GF Value™ of €44.73. GuruFocus considers Ionis Pharmaceuticals to be Modestly Overvalued.

Key valuation signals for MIL:1IONS:

  • Effective Interest Rate on Debt %: 3.73%
  • GF Value™: €44.73 vs. price of €48.44 (8.3% above fair value)
  • GF Score™: 48/100 with 5 warning signs

No single metric tells the full story. See the MIL:1IONS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ionis Pharmaceuticals Business Description

Other Exchanges IONS:USA0JDI:UKISI:Germany
Address 2855 Gazelle Court, Carlsbad, CA, USA, 92010
Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis marked its first two independent launches in 2025 for Tryngolza (for FCS) and Dawnzera (for HAE).
48GF Score

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Effective Interest Rate on Debt % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€48.44
Price
€44.73
GF Value