Alnylam Pharmaceuticals (MEX:ALNY) EV-to-EBITDA: 26.21 (As of Sep. 09, 2026)

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MEX:ALNY Alnylam Pharmaceuticals Inc MEX:ALNY
65 GF Score
Price MXN5,549.00
GF Value MXN11,444.89
! 1 Warning Sign
View Full Analysis

What is Alnylam Pharmaceuticals EV-to-EBITDA?

Alnylam Pharmaceuticals MEX:ALNY 65 EV-to-EBITDA is 26.21 as of Sep. 09, 2026. GuruFocus rates MEX:ALNY with a GF Score™ of 65/100 and a GF Value™ of MXN11,444.89. The stock has 1 warning sign investors should review. Among 400 Biotechnology companies, Alnylam Pharmaceuticals ranks worse than 68.25% on this metric.

EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Alnylam Pharmaceuticals's enterprise value is MXN555,363 Mil. Alnylam Pharmaceuticals's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 was MXN21,192 Mil. Therefore, Alnylam Pharmaceuticals's EV-to-EBITDA for today is 26.21.

The historical rank and industry rank for Alnylam Pharmaceuticals's EV-to-EBITDA or its related term are showing as below:

MEX:ALNY' s EV-to-EBITDA Range Over the Past 10 Years
Min: -613.3   Med: -20.68   Max: 276.8
Current: 27.78

During the past 13 years, the highest EV-to-EBITDA of Alnylam Pharmaceuticals was 276.80. The lowest was -613.30. And the median was -20.68.

MEX:ALNY's EV-to-EBITDA is ranked worse than
68.25% of 400 companies
in the Biotechnology industry
Industry Median: 13.615 vs MEX:ALNY: 27.78

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.

As of today (2026-09-09), Alnylam Pharmaceuticals's stock price is MXN5549.00. Alnylam Pharmaceuticals's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 was MXN96.681. Therefore, Alnylam Pharmaceuticals's PE Ratio (TTM) for today is 57.39.

The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).


Alnylam Pharmaceuticals  (MEX:ALNY) EV-to-EBITDA Explanation

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Alnylam Pharmaceuticals's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=5549.00/96.681
=57.39

Alnylam Pharmaceuticals's share price for today is MXN5549.00.
Alnylam Pharmaceuticals's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was MXN96.681.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).

Please read Which price ratio outperforms the enterprise multiple?


Alnylam Pharmaceuticals EV-to-EBITDA Related Terms


Alnylam Pharmaceuticals EV-to-EBITDA Historical Data

* Premium members only.

The historical data trend for Alnylam Pharmaceuticals's EV-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Alnylam Pharmaceuticals EV-to-EBITDA Chart

Alnylam Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBITDA
Get a 7-Day Free Trial Premium Member Only Premium Member Only -30.58 -30.84 -88.85 -162.29 80.78

Alnylam Pharmaceuticals Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -425.60 225.01 80.78 45.14 32.40

MEX:ALNY vs RPRX, INSM, BNTX: EV-to-EBITDA Comparison

For the Biotechnology subindustry, Alnylam Pharmaceuticals's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Alnylam Pharmaceuticals EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Alnylam Pharmaceuticals's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Alnylam Pharmaceuticals's EV-to-EBITDA falls into.


MEX:ALNY
65GF Score
Alnylam Pharmaceuticals Inc MEX:ALNY
EV-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Alnylam Pharmaceuticals EV-to-EBITDA Calculation

Alnylam Pharmaceuticals's EV-to-EBITDA for today is calculated as:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA (TTM)
=555362.567/21192.3
=26.21

Alnylam Pharmaceuticals's current Enterprise Value is MXN555,363 Mil.
Alnylam Pharmaceuticals's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was MXN21,192 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBITDA →
What does a EV-to-EBITDA of 26.21 mean?
Alnylam Pharmaceuticals (MEX:ALNY) has a EV-to-EBITDA of 26.21 as of Sep. 09, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Alnylam Pharmaceuticals. According to the industry distribution chart, Alnylam Pharmaceuticals ranks #273 out of 400 companies in the Biotechnology industry, placing it in the top 68.2%.
Is Alnylam Pharmaceuticals' EV-to-EBITDA too high?
Alnylam Pharmaceuticals' current EV-to-EBITDA is 26.21. The Biotechnology industry median EV-to-EBITDA is 13.62. Alnylam Pharmaceuticals' value of 26.21 is 92.5% above this industry median. Based on the distribution chart, Alnylam Pharmaceuticals ranks #273 out of 400 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Alnylam Pharmaceuticals has a GF Score™ of 65/100, reflecting its overall financial health beyond just this single metric.
How does Alnylam Pharmaceuticals' EV-to-EBITDA compare to RPRX and INSM?
According to the Biotechnology industry distribution chart, Alnylam Pharmaceuticals ranks #273 out of 400 companies for EV-to-EBITDA. This places Alnylam Pharmaceuticals in the lower half of its industry. The industry median EV-to-EBITDA is 13.62. Alnylam Pharmaceuticals' value of 26.21 is 92.5% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 13.62, based on 400 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Alnylam Pharmaceuticals's current EV-to-EBITDA of 26.21 is 92.5% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Alnylam Pharmaceuticals. For the Biotechnology industry, the median EV-to-EBITDA is 13.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Alnylam Pharmaceuticals's current EV-to-EBITDA is 26.21. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Alnylam Pharmaceuticals stock overvalued right now?
Alnylam Pharmaceuticals (MEX:ALNY) has a current EV-to-EBITDA of 26.21. The stock's GF Value™ is MXN11,444.89, compared to a current price of MXN5,549.00 — trading 51.5% below its estimated fair value. The current EV-to-EBITDA is 26.21 and 92.5% above the Biotechnology industry median of 13.62. Alnylam Pharmaceuticals' overall GF Score™ is 65/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Alnylam Pharmaceuticals (MEX:ALNY), the current EV-to-EBITDA is 26.21 as of Sep. 09, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Alnylam Pharmaceuticals (MEX:ALNY) Overvalued in 2026?

Based on GuruFocus' analysis, Alnylam Pharmaceuticals stock appears to be undervalued. The current stock price of MXN5,549.00 is trading 51.5% below its estimated GF Value™ of MXN11,444.89.

Key valuation signals for MEX:ALNY:

  • EV-to-EBITDA: 26.21
  • GF Value™: MXN11,444.89 vs. price of MXN5,549.00 (51.5% below fair value)
  • GF Score™: 65/100 with 1 warning sign
  • Industry Position: 92.5% above the Biotechnology median (#273 of 400)

No single metric tells the full story. See the MEX:ALNY stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Alnylam Pharmaceuticals Business Description

Address 675 West Kendall Street, Henri A. Termeer Square, Cambridge, MA, USA, 02142
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam's commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam's partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
65GF Score

Get the complete analysis for MEX:ALNY

EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN5,549.00
Price
MXN11,444.89
GF Value