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EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Clearside Biomedical's enterprise value is €-4.32 Mil.
Clearside Biomedical's EBITDA for the trailing twelve months (TTM) ended in Sep. 2025 was €-13.09 Mil. Therefore, Clearside Biomedical's EV-to-EBITDA for today is 0.33.
The historical rank and industry rank for Clearside Biomedical's EV-to-EBITDA or its related term are showing as below:
STU:CLM0'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -336.91 Med: -2.48 Max: 409.04
Current: 0.35
During the past 12 years, the highest EV-to-EBITDA of Clearside Biomedical was 409.04. The lowest was -336.91. And the median was -2.48.
STU:CLM0's EV-to-EBITDA is ranked better than 89.41% of 406
companies
in the Biotechnology industry
Industry Median: 14.4
vs STU:CLM0: 0.35
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Clearside Biomedical's PE Ratio (TTM) for today is calculated as:
Clearside Biomedical's share price for today is €4.35.
Clearside Biomedical's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Sep. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was €-4.710.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for Clearside Biomedical's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
STU:CLM0 vs RMTG, ABPO, SCNI: EV-to-EBITDA Comparison
For the Biotechnology subindustry, Clearside Biomedical's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Clearside Biomedical EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Clearside Biomedical's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Clearside Biomedical's EV-to-EBITDA falls into.
Clearside Biomedical's current Enterprise Value is €-4.32 Mil.
Clearside Biomedical's EBITDA for the trailing twelve months (TTM) ended in Sep. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was €-13.09 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Clearside Biomedical (STU:CLM0) has a EV-to-EBITDA of 0.33 as of Aug. 22, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Clearside Biomedical. According to the industry distribution chart, Clearside Biomedical ranks #43 out of 406 companies in the Biotechnology industry, placing it in the top 10.6%.
Is Clearside Biomedical's EV-to-EBITDA too high?
Clearside Biomedical's current EV-to-EBITDA is 0.33. The Biotechnology industry median EV-to-EBITDA is 14.40. Clearside Biomedical's value of 0.33 is 97.7% below this industry median. Based on the distribution chart, Clearside Biomedical ranks #43 out of 406 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Clearside Biomedical has a GF Score™ of 44/100, reflecting its overall financial health beyond just this single metric.
How does Clearside Biomedical's EV-to-EBITDA compare to RMTG and ABPO?
According to the Biotechnology industry distribution chart, Clearside Biomedical ranks #43 out of 406 companies for EV-to-EBITDA. This places Clearside Biomedical in the top 11% of its industry — outperforming the majority of peers. The industry median EV-to-EBITDA is 14.40. Clearside Biomedical's value of 0.33 is 97.7% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 14.40, based on 406 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Clearside Biomedical's current EV-to-EBITDA of 0.33 is 97.7% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Clearside Biomedical. For the Biotechnology industry, the median EV-to-EBITDA is 14.40 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Clearside Biomedical's current EV-to-EBITDA is 0.33. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Clearside Biomedical stock overvalued right now?
Clearside Biomedical (STU:CLM0) has a current EV-to-EBITDA of 0.33. The stock's GF Value™ is €108.49, compared to a current price of €4.35 — trading 96% below its estimated fair value. The current EV-to-EBITDA is 0.33 and 97.7% below the Biotechnology industry median of 14.40. Clearside Biomedical's overall GF Score™ is 44/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Clearside Biomedical (STU:CLM0), the current EV-to-EBITDA is 0.33 as of Aug. 22, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Clearside Biomedical (STU:CLM0) Overvalued in 2026?
Based on GuruFocus' analysis, Clearside Biomedical stock appears to be undervalued.
The current stock price of €4.35 is trading 96% below its estimated GF Value™ of €108.49.
Key valuation signals for STU:CLM0:
EV-to-EBITDA: 0.33
GF Value™: €108.49 vs. price of €4.35 (96% below fair value)
Industry Position: 97.7% below the Biotechnology median (#43 of 406)
No single metric tells the full story. See the STU:CLM0 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Clearside Biomedical Inc is a United States-based clinical biopharmaceutical company. It is engaged in developing pharmacological therapies to treat blinding disease of the eye through the suprachoroidal space, or SCS. The company's novel SCS injection platform, utilizing a proprietary SCS Microinjector, enables an in-office, repeatable, non-surgical procedure for the targeted and compartmentalized delivery of a wide variety of therapies to the macula, retina, or choroid to potentially preserve and improve vision in patients with sight-threatening eye diseases.
44GF Score
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