Clearside Biomedical (STU:CLM0) Operating Income: €-20.73 Mil (TTM As of Sep. 2025)

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STU:CLM0 Clearside Biomedical Inc STU:CLM0
44 GF Score
Price €4.35
GF Value €110.06
! 7 Warning Signs
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What is Clearside Biomedical Operating Income?

Clearside Biomedical STU:CLM0 44 Operating Income is €-20.73 Mil as of Sep. 2025. GuruFocus rates STU:CLM0 with a GF Score™ of 44/100 and a GF Value™ of €110.06. The stock has 7 warning signs investors should review.

Clearside Biomedical's Operating Income for the three months ended in Sep. 2025 was €-6.00 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Sep. 2025 was €-20.73 Mil.

Operating Margin % is calculated as Operating Income divided by its Revenue. Clearside Biomedical's Operating Income for the three months ended in Sep. 2025 was €-6.00 Mil. Clearside Biomedical's Revenue for the three months ended in Sep. 2025 was €0.17 Mil. Therefore, Clearside Biomedical's Operating Margin % for the quarter that ended in Sep. 2025 was -3,507.60%.

Warning Sign:

Clearside Biomedical Inc operating margin has been in a 5-year decline. The average rate of decline per year is -29.1%.

Clearside Biomedical's 5-Year average Growth Rate for Operating Margin % was -29.10% per year.

Operating Income or EBIT is linked to Return on Capital for both regular definition and Joel Greenblatt's definition. Clearside Biomedical's annualized ROC % for the quarter that ended in Sep. 2025 was -707.00%. Clearside Biomedical's annualized ROC (Joel Greenblatt) % for the quarter that ended in Sep. 2025 was -392.49%.


Clearside Biomedical  (STU:CLM0) Operating Income Explanation

1. Operating Income or EBIT is linked to Return on Capital for both regular definition and Joel Greenblatt's definition.

Clearside Biomedical's annualized ROC % for the quarter that ended in Sep. 2025 is calculated as:

ROC % (Q: Sep. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Jun. 2025 ) + Invested Capital (Q: Sep. 2025 ))/ count )
=-23.992 * ( 1 - 0% )/( (3.574 + 3.213)/ 2 )
=-23.992/3.3935
=-707.00 %

where

Note: The Operating Income data used here is four times the quarterly (Sep. 2025) data.

2. Joel Greenblatt's definition of Return on Capital:

Clearside Biomedical's annualized ROC (Joel Greenblatt) % for the quarter that ended in Sep. 2025 is calculated as:

ROC (Joel Greenblatt) %(Q: Sep. 2025 )
=EBIT/Average of (Net fixed Assets + Net Working Capital)
=EBIT/Average of (Property, Plant and Equipment+Net Working Capital)
     Q: Jun. 2025  Q: Sep. 2025
=EBIT/( ( (Property, Plant and Equipment + Net Working Capital) + (Property, Plant and Equipment + Net Working Capital) )/ count )
=-11.596/( ( (3.049 + max(-0.223, 0)) + (2.86 + max(-0.795, 0)) )/ 2 )
=-11.596/( ( 3.049 + 2.86 )/ 2 )
=-11.596/2.9545
=-392.49 %

where Working Capital is:

Working Capital(Q: Jun. 2025 )
=(Accounts Receivable + Total Inventories + Other Current Assets) - (Accounts Payable & Accrued Expense + Defer. Rev. + Other Current Liabilities)
=(0.707 + 0 + 1.382) - (2.143 + 0 + 0.169)
=-0.223

Working Capital(Q: Sep. 2025 )
=(Accounts Receivable + Total Inventories + Other Current Assets) - (Accounts Payable & Accrued Expense + Defer. Rev. + Other Current Liabilities)
=(0.227 + 0 + 1.011) - (2.033 + 0 + 0)
=-0.795

When net working capital is negative, 0 is used.

Note: The EBIT data used here is four times the quarterly (Sep. 2025) EBIT data.

3. Operating Income is also linked to Operating Margin %:

Clearside Biomedical's Operating Margin % for the quarter that ended in Sep. 2025 is calculated as:

Operating Margin %=Operating Income (Q: Sep. 2025 )/Revenue (Q: Sep. 2025 )
=-5.998/0.171
=-3,507.60 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

4. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Operating Income growth rate using Operating Income per share data.


Be Aware

Compared with a company's EBITDA margin, Operating Margin can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin may decline. Often the Operating Margin declines well before the company's revenue or even profit decline. Therefore, Operating Margin is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia's Operating Margin had already been in decline since 2002, although its earnings per share were still rising. Investors who paid attention to Operating Margin would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Clearside Biomedical Operating Income Related Terms


Clearside Biomedical Operating Income Historical Data

* Premium members only.

The historical data trend for Clearside Biomedical's Operating Income can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Clearside Biomedical Operating Income Chart

Clearside Biomedical Annual Data
Trend Dec15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24
Operating Income
Get a 7-Day Free Trial Premium Member Only Premium Member Only -14.74 -0.56 -28.58 -22.78 -27.58

Clearside Biomedical Quarterly Data
Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25
Operating Income Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -5.35 -6.83 -4.82 -3.09 -6.00
STU:CLM0
44GF Score
Clearside Biomedical Inc STU:CLM0
Operating Income is just one metric. See GF Score™, valuation, warning signs, and more.
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Clearside Biomedical Operating Income Calculation

Operating Income, is the profit a company earned through operations. All expenses, including cash expenses such as cost of goods sold (COGS), research & development, wages, and non-cash expenses, such as depreciation, depletion and amortization, have been deducted from the sales.

Operating Income for the trailing twelve months (TTM) ended in Sep. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was €-20.73 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Income →
What does a Operating Income of €-20.73 Mil mean?
Clearside Biomedical (STU:CLM0) has a Operating Income of €-20.73 Mil as of Sep. 2025. Operating Income equals sales less all operating expenses. It is linked to EBIT. View historical data on Clearside Biomedical and its competitors.
Is Clearside Biomedical's Operating Income too high?
Clearside Biomedical's current Operating Income is €-20.73 Mil. Overall, Clearside Biomedical has a GF Score™ of 44/100, reflecting its overall financial health beyond just this single metric.
How does Clearside Biomedical's Operating Income compare to RMTG and ABPO?
Clearside Biomedical's Operating Income of €-20.73 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Income for a Biotechnology company?
A good Operating Income depends on the Biotechnology industry context. However, Operating Income should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Income mean?
A high Operating Income can signal that a stock is expensive relative to its fundamentals. Operating Income equals sales less all operating expenses. It is linked to EBIT. View historical data on Clearside Biomedical and its competitors. Clearside Biomedical's current Operating Income is €-20.73 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Clearside Biomedical stock overvalued right now?
Clearside Biomedical (STU:CLM0) has a current Operating Income of €-20.73 Mil. The stock's GF Value™ is €110.06, compared to a current price of €4.35 — trading 96% below its estimated fair value. The current Operating Income is €-20.73 Mil. Clearside Biomedical's overall GF Score™ is 44/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Income calculated?
Operating Income is calculated from a company's financial statements. For Clearside Biomedical (STU:CLM0), the current Operating Income is €-20.73 Mil as of Sep. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Clearside Biomedical (STU:CLM0) Overvalued in 2026?

Based on GuruFocus' analysis, Clearside Biomedical stock appears to be undervalued. The current stock price of €4.35 is trading 96% below its estimated GF Value™ of €110.06.

Key valuation signals for STU:CLM0:

  • Operating Income: €-20.73 Mil
  • GF Value™: €110.06 vs. price of €4.35 (96% below fair value)
  • GF Score™: 44/100 with 7 warning signs

No single metric tells the full story. See the STU:CLM0 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Clearside Biomedical Business Description

Other Exchanges CLSDQ:USA
Address 900 North Point Parkway, Suite 200, Alpharetta, GA, USA, 30005
Clearside Biomedical Inc is a United States-based clinical biopharmaceutical company. It is engaged in developing pharmacological therapies to treat blinding disease of the eye through the suprachoroidal space, or SCS. The company's novel SCS injection platform, utilizing a proprietary SCS Microinjector, enables an in-office, repeatable, non-surgical procedure for the targeted and compartmentalized delivery of a wide variety of therapies to the macula, retina, or choroid to potentially preserve and improve vision in patients with sight-threatening eye diseases.
44GF Score

Get the complete analysis for STU:CLM0

Operating Income is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€4.35
Price
€110.06
GF Value