Noile-Immune Biotech (TSE:4893) EV-to-EBITDA: -4.26 (As of Sep. 01, 2026)

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TSE:4893 Noile-Immune Biotech Inc TSE:4893
45 GF Score
Price 円156.00
GF Value 円15.54
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is Noile-Immune Biotech EV-to-EBITDA?

Noile-Immune Biotech TSE:4893 +5.41% 45 EV-to-EBITDA is -4.26 as of Sep. 01, 2026. GuruFocus rates TSE:4893 with a GF Score™ of 45/100 and a GF Value™ of 円15.54 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 402 Biotechnology companies, Noile-Immune Biotech ranks worse than 248755.97% on this metric.

EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Noile-Immune Biotech's enterprise value is 円3,225.28 Mil. Noile-Immune Biotech's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 was 円-757.71 Mil. Therefore, Noile-Immune Biotech's EV-to-EBITDA for today is -4.26.

The historical rank and industry rank for Noile-Immune Biotech's EV-to-EBITDA or its related term are showing as below:

TSE:4893' s EV-to-EBITDA Range Over the Past 10 Years
Min: -22.59   Med: -3.63   Max: -0.51
Current: -4.26

During the past 6 years, the highest EV-to-EBITDA of Noile-Immune Biotech was -0.51. The lowest was -22.59. And the median was -3.63.

TSE:4893's EV-to-EBITDA is ranked worse than
100% of 402 companies
in the Biotechnology industry
Industry Median: 13.8 vs TSE:4893: -4.26

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.

As of today (2026-09-01), Noile-Immune Biotech's stock price is 円156.00. Noile-Immune Biotech's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 was 円-16.320. Therefore, Noile-Immune Biotech's PE Ratio (TTM) for today is At Loss.

The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).


Noile-Immune Biotech  (TSE:4893) EV-to-EBITDA Explanation

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Noile-Immune Biotech's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=156.00/-16.320
=At Loss

Noile-Immune Biotech's share price for today is 円156.00.
Noile-Immune Biotech's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-16.320.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).

Please read Which price ratio outperforms the enterprise multiple?


Noile-Immune Biotech EV-to-EBITDA Related Terms


Noile-Immune Biotech EV-to-EBITDA Historical Data

* Premium members only.

The historical data trend for Noile-Immune Biotech's EV-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Noile-Immune Biotech EV-to-EBITDA Chart

Noile-Immune Biotech Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBITDA
Get a 7-Day Free Trial 0.00 0.00 -4.67 -2.52 -2.31

Noile-Immune Biotech Quarterly Data
Dec20 Dec21 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -7.49 -6.04 -2.31 -3.29 -2.91

TSE:4893 vs VRTX, REGN, MRNA: EV-to-EBITDA Comparison

For the Biotechnology subindustry, Noile-Immune Biotech's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Noile-Immune Biotech EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Noile-Immune Biotech's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Noile-Immune Biotech's EV-to-EBITDA falls into.


TSE:4893
45GF Score
Noile-Immune Biotech Inc TSE:4893
EV-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Noile-Immune Biotech EV-to-EBITDA Calculation

Noile-Immune Biotech's EV-to-EBITDA for today is calculated as:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA (TTM)
=3225.279/-757.709
=-4.26

Noile-Immune Biotech's current Enterprise Value is 円3,225.28 Mil.
Noile-Immune Biotech's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-757.71 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBITDA →
What does a EV-to-EBITDA of -4.26 mean?
Noile-Immune Biotech (TSE:4893) has a EV-to-EBITDA of -4.26 as of Sep. 01, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Noile-Immune Biotech. According to the industry distribution chart, Noile-Immune Biotech ranks #999999 out of 402 companies in the Biotechnology industry.
Is Noile-Immune Biotech's EV-to-EBITDA too high?
Noile-Immune Biotech's current EV-to-EBITDA is -4.26. Based on the distribution chart, Noile-Immune Biotech ranks #999999 out of 402 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Noile-Immune Biotech has a GF Score™ of 45/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Noile-Immune Biotech's EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Noile-Immune Biotech ranks #999999 out of 402 companies for EV-to-EBITDA. This places Noile-Immune Biotech in the lower half of its industry. The industry median EV-to-EBITDA is 13.80. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 13.80, based on 402 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Noile-Immune Biotech. For the Biotechnology industry, the median EV-to-EBITDA is 13.80 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Noile-Immune Biotech's current EV-to-EBITDA is -4.26. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Noile-Immune Biotech stock overvalued right now?
Based on GuruFocus' analysis, Noile-Immune Biotech (TSE:4893) is currently considered Significantly Overvalued. The stock's GF Value™ is 円15.54, compared to a current price of 円156.00 — trading 903.9% above its estimated fair value. The current EV-to-EBITDA is -4.26. Noile-Immune Biotech's overall GF Score™ is 45/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Noile-Immune Biotech (TSE:4893), the current EV-to-EBITDA is -4.26 as of Sep. 01, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Noile-Immune Biotech (TSE:4893) Overvalued in 2026?

Based on GuruFocus' analysis, Noile-Immune Biotech stock appears to be overvalued. The current stock price of 円156.00 is trading 903.9% above its estimated GF Value™ of 円15.54. GuruFocus considers Noile-Immune Biotech to be Significantly Overvalued.

Key valuation signals for TSE:4893:

  • EV-to-EBITDA: -4.26
  • GF Value™: 円15.54 vs. price of 円156.00 (903.9% above fair value)
  • GF Score™: 45/100 with 4 warning signs

No single metric tells the full story. See the TSE:4893 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Noile-Immune Biotech Business Description

Address 2-12-10 Shiba-Daimon, 5th Floor, T&G Hamamatsucho Building, Minato-ku, Yamaguchi, Tokyo, JPN, 105-0012
Noile-Immune Biotech Inc is engaged in the development of CAR-T cell therapy for solid cancers using its proprietary technology. The company's development pipeline and collaborative projects with other companies include different product candidates such as NIB102, NIB103, NIB104, ADAP01, AUTL01, etc. It operates in a single segment, the cancer immunotherapy drug discovery business.
45GF Score

Get the complete analysis for TSE:4893

EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円156.00
Price
円15.54
GF Value