Noile-Immune Biotech (TSE:4893) ROC %: 0.00% (As of Dec. 2025)


TSE:4893 Noile-Immune Biotech Inc TSE:4893
54 GF Score
Price 円120.00
GF Value 円4.38
Valuation Significantly Overvalued
! 2 Warning Signs
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What is Noile-Immune Biotech ROC %?

Noile-Immune Biotech TSE:4893 +0.84% 54 ROC % is 0.00% as of Dec. 2025. GuruFocus rates TSE:4893 with a GF Score™ of 54/100 and a GF Value™ of 円4.38 (Significantly Overvalued). The stock has 2 warning signs investors should review.

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. Noile-Immune Biotech's annualized return on capital (ROC %) for the quarter that ended in Dec. 2025 was 0.00%.

As of today (2026-06-27), Noile-Immune Biotech's WACC % is 4.61%. Noile-Immune Biotech's ROC % is -554.73% (calculated using TTM income statement data). Noile-Immune Biotech earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Noile-Immune Biotech  (TSE:4893) ROC % Explanation

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, Noile-Immune Biotech's WACC % is 4.61%. Noile-Immune Biotech's ROC % is -554.73% (calculated using TTM income statement data). Noile-Immune Biotech earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Be Aware

Like ROE % and ROA %, ROC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


Noile-Immune Biotech ROC % Related Terms


Noile-Immune Biotech ROC % Historical Data

* Premium members only.

The historical data trend for Noile-Immune Biotech's ROC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Noile-Immune Biotech ROC % Chart

Noile-Immune Biotech Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROC %
Get a 7-Day Free Trial -807.16 -90.95 -469.60 -787.73 -996.98

Noile-Immune Biotech Quarterly Data
Dec20 Dec21 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Dec25 Mar26
ROC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -1,139.23 -1,052.82 0.00 -1,162.36
TSE:4893
54GF Score
Noile-Immune Biotech Inc TSE:4893
ROC % is just one metric. See GF Score™, valuation, warning signs, and more.
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Noile-Immune Biotech ROC % Calculation

Noile-Immune Biotech's annualized Return on Capital (ROC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=-797.254 * ( 1 - 0% )/( (97.128999999999 + 62.804000000001)/ 2 )
=-797.254/79.9665
=-996.98 %

where

Invested Capital(A: Dec. 2024 )
=Total Assets - Accounts Payable & Accrued Expense - Excess Cash
=Total Assets - Accounts Payable & Accrued Expense - ( Cash, Cash Equivalents, Marketable Securities - max(0, Total Current Liabilities - Total Current Assets+Cash, Cash Equivalents, Marketable Securities))
=4800.172 - 32.104 - ( 4670.939 - max(0, 69.441 - 4775.376+4670.939))
=97.128999999999

Invested Capital(A: Dec. 2025 )
=Total Assets - Accounts Payable & Accrued Expense - Excess Cash
=Total Assets - Accounts Payable & Accrued Expense - ( Cash, Cash Equivalents, Marketable Securities - max(0, Total Current Liabilities - Total Current Assets+Cash, Cash Equivalents, Marketable Securities))
=4011.579 - 39.74 - ( 3918.321 - max(0, 74.405 - 3983.44+3918.321))
=62.804000000001

Noile-Immune Biotech's annualized Return on Capital (ROC %) for the quarter that ended in Dec. 2025 is calculated as:

ROC % (Q: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Jun. 2025 ) + Invested Capital (Q: Dec. 2025 ))/ count )
=0 * ( 1 - 0% )/( (57.407 + 62.804000000001)/ 2 )
=0/60.1055
=0.00 %

where

Invested Capital(Q: Dec. 2025 )
=Total Assets - Accounts Payable & Accrued Expense - Excess Cash
=Total Assets - Accounts Payable & Accrued Expense - ( Cash, Cash Equivalents, Marketable Securities - max(0, Total Current Liabilities - Total Current Assets+Cash, Cash Equivalents, Marketable Securities))
=4011.579 - 39.74 - ( 3918.321 - max(0, 74.405 - 3983.44+3918.321))
=62.804000000001

Note: The Operating Income data used here is four times the quarterly (Dec. 2025) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROC % →
What does a ROC % of 0.00% mean?
Noile-Immune Biotech (TSE:4893) has a ROC % of 0.00% as of Dec. 2025. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on Noile-Immune Biotech and its competitors.
Is Noile-Immune Biotech's ROC % too high?
Noile-Immune Biotech's current ROC % is 0.00%. Overall, Noile-Immune Biotech has a GF Score™ of 54/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Noile-Immune Biotech's ROC % compare to VRTX and REGN?
Noile-Immune Biotech's ROC % of 0.00% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROC % for a Biotechnology company?
A good ROC % depends on the Biotechnology industry context. However, ROC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROC % mean?
A high ROC % can signal that a stock is expensive relative to its fundamentals. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on Noile-Immune Biotech and its competitors. Noile-Immune Biotech's current ROC % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Noile-Immune Biotech stock overvalued right now?
Based on GuruFocus' analysis, Noile-Immune Biotech (TSE:4893) is currently considered Significantly Overvalued. The stock's GF Value™ is 円4.38, compared to a current price of 円120.00 — trading 2639.7% above its estimated fair value. The current ROC % is 0.00%. Noile-Immune Biotech's overall GF Score™ is 54/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROC % calculated?
ROC % is calculated from a company's financial statements. For Noile-Immune Biotech (TSE:4893), the current ROC % is 0.00% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Noile-Immune Biotech (TSE:4893) Overvalued in 2026?

Based on GuruFocus' analysis, Noile-Immune Biotech stock appears to be overvalued. The current stock price of 円120.00 is trading 2639.7% above its estimated GF Value™ of 円4.38. GuruFocus considers Noile-Immune Biotech to be Significantly Overvalued.

Key valuation signals for TSE:4893:

  • ROC %: 0.00%
  • GF Value™: 円4.38 vs. price of 円120.00 (2639.7% above fair value)
  • GF Score™: 54/100 with 2 warning signs

No single metric tells the full story. See the TSE:4893 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Noile-Immune Biotech Business Description

Address 2-12-10 Shiba-Daimon, 5th Floor, T&G Hamamatsucho Building, Minato-ku, Yamaguchi, Tokyo, JPN, 105-0012
Noile-Immune Biotech Inc is engaged in the development of CAR-T cell therapy for solid cancers using its proprietary technology. The company's development pipeline and collaborative projects with other companies include different product candidates such as NIB102, NIB103, NIB104, ADAP01, AUTL01, etc. It operates in a single segment, the cancer immunotherapy drug discovery business.
54GF Score

Get the complete analysis for TSE:4893

ROC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円120.00
Price
円4.38
GF Value