Noile-Immune Biotech (TSE:4893) ROE % Adjusted to Book Value: 0.00% (As of Dec. 2025)


TSE:4893 Noile-Immune Biotech Inc TSE:4893
53 GF Score
Price 円128.00
GF Value 円4.35
Valuation Significantly Overvalued
! 2 Warning Signs
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What is Noile-Immune Biotech ROE % Adjusted to Book Value?

Noile-Immune Biotech TSE:4893 53 ROE % Adjusted to Book Value is 0.00% as of Dec. 2025. GuruFocus rates TSE:4893 with a GF Score™ of 53/100 and a GF Value™ of 円4.35 (Significantly Overvalued). The stock has 2 warning signs investors should review.

Noile-Immune Biotech's ROE % for the quarter that ended in Dec. 2025 was 0.00%. Noile-Immune Biotech's PB Ratio for the quarter that ended in Dec. 2025 was 1.46. Noile-Immune Biotech's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 was 0.00%.


Noile-Immune Biotech ROE % Adjusted to Book Value Related Terms


Noile-Immune Biotech ROE % Adjusted to Book Value Historical Data

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The historical data trend for Noile-Immune Biotech's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Noile-Immune Biotech ROE % Adjusted to Book Value Chart

Noile-Immune Biotech Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial 0.00 0.00 -14.06 -11.87 -12.55

Noile-Immune Biotech Quarterly Data
Dec20 Dec21 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -13.46 -9.06 0.00 -9.65

TSE:4893 vs VRTX, REGN, ALNY: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Noile-Immune Biotech's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Noile-Immune Biotech ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Noile-Immune Biotech's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Noile-Immune Biotech's ROE % Adjusted to Book Value falls into.


TSE:4893
53GF Score
Noile-Immune Biotech Inc TSE:4893
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Noile-Immune Biotech ROE % Adjusted to Book Value Calculation

Noile-Immune Biotech's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-18.33% / 1.46
=-12.55%

Noile-Immune Biotech's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=0.00% / 1.46
=0.00%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of 0.00% mean?
Noile-Immune Biotech (TSE:4893) has a ROE % Adjusted to Book Value of 0.00% as of Dec. 2025. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Noile-Immune Biotech and its competitors.
Is Noile-Immune Biotech's ROE % Adjusted to Book Value too high?
Noile-Immune Biotech's current ROE % Adjusted to Book Value is 0.00%. Overall, Noile-Immune Biotech has a GF Score™ of 53/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Noile-Immune Biotech's ROE % Adjusted to Book Value compare to VRTX and REGN?
Noile-Immune Biotech's ROE % Adjusted to Book Value of 0.00% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Noile-Immune Biotech and its competitors. Noile-Immune Biotech's current ROE % Adjusted to Book Value is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Noile-Immune Biotech stock overvalued right now?
Based on GuruFocus' analysis, Noile-Immune Biotech (TSE:4893) is currently considered Significantly Overvalued. The stock's GF Value™ is 円4.35, compared to a current price of 円128.00 — trading 2842.5% above its estimated fair value. The current ROE % Adjusted to Book Value is 0.00%. Noile-Immune Biotech's overall GF Score™ is 53/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Noile-Immune Biotech (TSE:4893), the current ROE % Adjusted to Book Value is 0.00% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Noile-Immune Biotech (TSE:4893) Overvalued in 2026?

Based on GuruFocus' analysis, Noile-Immune Biotech stock appears to be overvalued. The current stock price of 円128.00 is trading 2842.5% above its estimated GF Value™ of 円4.35. GuruFocus considers Noile-Immune Biotech to be Significantly Overvalued.

Key valuation signals for TSE:4893:

  • ROE % Adjusted to Book Value: 0.00%
  • GF Value™: 円4.35 vs. price of 円128.00 (2842.5% above fair value)
  • GF Score™: 53/100 with 2 warning signs

No single metric tells the full story. See the TSE:4893 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Noile-Immune Biotech Business Description

Address 2-12-10 Shiba-Daimon, 5th Floor, T&G Hamamatsucho Building, Minato-ku, Yamaguchi, Tokyo, JPN, 105-0012
Noile-Immune Biotech Inc is engaged in the development of CAR-T cell therapy for solid cancers using its proprietary technology. The company's development pipeline and collaborative projects with other companies include different product candidates such as NIB102, NIB103, NIB104, ADAP01, AUTL01, etc. It operates in a single segment, the cancer immunotherapy drug discovery business.
53GF Score

Get the complete analysis for TSE:4893

ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円128.00
Price
円4.35
GF Value