ANAB (AnaptysBio) EV-to-OCF: 313.90 (As of Aug. 20, 2026)

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ANAB AnaptysBio Inc ANAB
40 GF Score
Price $56.69
! 2 Warning Signs
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What is AnaptysBio EV-to-OCF?

AnaptysBio ANAB -4.34% 40 EV-to-OCF is 313.90 as of Aug. 20, 2026. GuruFocus rates ANAB with a GF Score™ of 40/100. The stock has 2 warning signs investors should review. Among 1,409 Biotechnology companies, AnaptysBio ranks worse than 99.29% on this metric.

EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, AnaptysBio's Enterprise Value is $1,405.7 Mil. AnaptysBio's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 was $4.5 Mil. Therefore, AnaptysBio's EV-to-OCF for today is 313.90.

The historical rank and industry rank for AnaptysBio's EV-to-OCF or its related term are showing as below:

ANAB' s EV-to-OCF Range Over the Past 10 Years
Min: -89.9   Med: -0.88   Max: 383.27
Current: 313.9

During the past 13 years, the highest EV-to-OCF of AnaptysBio was 383.27. The lowest was -89.90. And the median was -0.88.

ANAB's EV-to-OCF is ranked worse than
99.29% of 1409 companies
in the Biotechnology industry
Industry Median: -3.66 vs ANAB: 313.90

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

As of today (2026-08-20), AnaptysBio's stock price is $56.69. AnaptysBio's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was $-1.080. Therefore, AnaptysBio's PE Ratio (TTM) for today is At Loss.


AnaptysBio  (NAS:ANAB) EV-to-OCF Explanation

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

AnaptysBio's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=56.69/-1.080
=At Loss

AnaptysBio's share price for today is $56.69.
AnaptysBio's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.080.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.


AnaptysBio EV-to-OCF Related Terms


AnaptysBio EV-to-OCF Historical Data

* Premium members only.

The historical data trend for AnaptysBio's EV-to-OCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

AnaptysBio EV-to-OCF Chart

AnaptysBio Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-OCF
Get a 7-Day Free Trial Premium Member Only Premium Member Only -2.47 -2.27 -0.06 0.74 30.86

AnaptysBio Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-OCF Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.48 -1.28 -2.27 30.86 178.73

ANAB vs MLTX, ABCL, TSHA: EV-to-OCF Comparison

For the Biotechnology subindustry, AnaptysBio's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


AnaptysBio EV-to-OCF vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, AnaptysBio's EV-to-OCF distribution charts can be found below:

* The bar in red indicates where AnaptysBio's EV-to-OCF falls into.


ANAB
40GF Score
AnaptysBio Inc ANAB
EV-to-OCF is just one metric. See GF Score™, valuation, warning signs, and more.
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AnaptysBio EV-to-OCF Calculation

AnaptysBio's EV-to-OCF for today is calculated as:

EV-to-OCF=Enterprise Value (Today)/Cash Flow from Operations (TTM)
=1405.663/4.478
=313.90

AnaptysBio's current Enterprise Value is $1,405.7 Mil.
AnaptysBio's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $4.5 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-OCF →
What does a EV-to-OCF of 313.90 mean?
AnaptysBio (ANAB) has a EV-to-OCF of 313.90 as of Aug. 20, 2026. According to the industry distribution chart, AnaptysBio ranks #1399 out of 1409 companies in the Biotechnology industry, placing it in the top 99.3%.
Is AnaptysBio's EV-to-OCF too high?
AnaptysBio's current EV-to-OCF is 313.90. Based on the distribution chart, AnaptysBio ranks #1399 out of 1409 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, AnaptysBio has a GF Score™ of 40/100, reflecting its overall financial health beyond just this single metric.
How does AnaptysBio's EV-to-OCF compare to MLTX and ABCL?
According to the Biotechnology industry distribution chart, AnaptysBio ranks #1399 out of 1409 companies for EV-to-OCF. This places AnaptysBio in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. AnaptysBio's current EV-to-OCF is 313.90. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is AnaptysBio stock overvalued right now?
AnaptysBio (ANAB) has a current EV-to-OCF of 313.90. The current EV-to-OCF is 313.90. AnaptysBio's overall GF Score™ is 40/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For AnaptysBio (ANAB), the current EV-to-OCF is 313.90 as of Aug. 20, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

AnaptysBio Business Description

Other Exchanges 0HFQ:UKAN6:Germany
Address 10770 Wateridge Circle, Suite 210, San Diego, CA, USA, 92121
AnaptysBio Inc is a clinical-stage biotechnology company. The company is focused on developing antibody product candidates for unmet medical needs in inflammation and immuno-oncology. The company is developing immune cell modulating antibodies, including two wholly owned checkpoint agonists in clinical-stage development, for autoimmune and inflammatory diseases; rosnilimab, PD-1 agonist in a Phase 2b trial for the treatment of moderate-to-severe rheumatoid arthritis (RA) and a Phase 2 trial for the treatment of moderate-to-severe ulcerative colitis (UC); and ANB032, BTLA agonist, in a Phase 2b trial for the treatment of moderate-to-severe atopic dermatitis (AD).
40GF Score

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EV-to-OCF is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$56.69
Price