ANAB (AnaptysBio) Cyclically Adjusted Book per Share: $10.36 (As of Mar. 2026)


ANAB AnaptysBio Inc ANAB
66 GF Score
Price $67.50
GF Value $61.78
Valuation Fairly Valued
! 5 Warning Signs
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What is AnaptysBio Cyclically Adjusted Book per Share?

AnaptysBio ANAB +2.33% 66 Cyclically Adjusted Book per Share is $10.36 as of Mar. 2026. GuruFocus rates ANAB with a GF Score™ of 66/100 and a GF Value™ of $61.78 (Fairly Valued). The stock has 5 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

AnaptysBio's adjusted book value per share for the three months ended in Mar. 2026 was $0.439. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $10.36 for the trailing ten years ended in Mar. 2026.

During the past 12 months, AnaptysBio's average Cyclically Adjusted Book Growth Rate was 5.60% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

As of today (2026-07-01), AnaptysBio's current stock price is $67.50. AnaptysBio's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $10.36. AnaptysBio's Cyclically Adjusted PB Ratio of today is 6.52.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of AnaptysBio was 6.69. The lowest was 0.89. And the median was 1.75.


AnaptysBio  (NAS:ANAB) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

AnaptysBio's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=67.50/10.36
=6.52

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of AnaptysBio was 6.69. The lowest was 0.89. And the median was 1.75.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


AnaptysBio Cyclically Adjusted Book per Share Related Terms


AnaptysBio Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for AnaptysBio's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

AnaptysBio Cyclically Adjusted Book per Share Chart

AnaptysBio Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 9.90 10.09

AnaptysBio Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 9.81 9.91 10.02 10.09 10.36

ANAB vs ABSI, TSHA, RXRX: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, AnaptysBio's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


AnaptysBio Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, AnaptysBio's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where AnaptysBio's Cyclically Adjusted PB Ratio falls into.


ANAB
66GF Score
AnaptysBio Inc ANAB
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

AnaptysBio Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, AnaptysBio's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book= Book Value per Share /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.439/330.2130*330.2130
=0.439

Current CPI (Mar. 2026) = 330.2130.

AnaptysBio Quarterly Data

Book Value per Share CPI Adj_Book
201606 -1.824 241.018 -2.499
201609 2.465 241.428 3.372
201612 -2.106 241.432 -2.880
201703 5.438 243.801 7.365
201706 5.381 244.955 7.254
201709 4.945 246.819 6.616
201712 12.928 246.524 17.317
201803 12.366 249.554 16.363
201806 11.860 251.989 15.542
201809 18.680 252.439 24.435
201812 18.066 251.233 23.745
201903 17.335 254.202 22.518
201906 16.581 256.143 21.376
201909 15.532 256.759 19.975
201912 14.860 256.974 19.095
202003 14.685 258.115 18.787
202006 13.979 257.797 17.906
202009 13.174 260.280 16.714
202012 14.503 260.474 18.386
202103 13.956 264.877 17.398
202106 14.061 271.696 17.089
202109 13.973 274.310 16.821
202112 12.892 278.802 15.269
202203 11.738 287.504 13.482
202206 10.779 296.311 12.012
202209 9.791 296.808 10.893
202212 9.192 296.797 10.227
202303 7.073 301.836 7.738
202306 5.595 305.109 6.055
202309 4.530 307.789 4.860
202312 3.313 306.746 3.566
202403 1.749 312.332 1.849
202406 0.360 314.175 0.378
202409 2.773 315.301 2.904
202412 2.326 315.605 2.434
202503 1.120 319.799 1.156
202506 -1.599 322.561 -1.637
202509 -1.067 324.800 -1.085
202512 1.328 324.054 1.353
202603 0.439 330.213 0.439

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of $10.36 mean?
AnaptysBio (ANAB) has a Cyclically Adjusted Book per Share of $10.36 as of Mar. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on AnaptysBio and its competitors.
Is AnaptysBio's Cyclically Adjusted Book per Share too high?
AnaptysBio's current Cyclically Adjusted Book per Share is $10.36. Overall, AnaptysBio has a GF Score™ of 66/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does AnaptysBio's Cyclically Adjusted Book per Share compare to ABSI and TSHA?
AnaptysBio's Cyclically Adjusted Book per Share of $10.36 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on AnaptysBio and its competitors. AnaptysBio's current Cyclically Adjusted Book per Share is $10.36. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is AnaptysBio stock overvalued right now?
Based on GuruFocus' analysis, AnaptysBio (ANAB) is currently considered Fairly Valued. The stock's GF Value™ is $61.78, compared to a current price of $67.50 — trading 9.3% above its estimated fair value. The current Cyclically Adjusted Book per Share is $10.36. AnaptysBio's overall GF Score™ is 66/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For AnaptysBio (ANAB), the current Cyclically Adjusted Book per Share is $10.36 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is AnaptysBio (ANAB) Overvalued in 2026?

Based on GuruFocus' analysis, AnaptysBio stock appears to be overvalued. The current stock price of $67.50 is trading 9.3% above its estimated GF Value™ of $61.78. GuruFocus considers AnaptysBio to be Fairly Valued.

Key valuation signals for ANAB:

  • Cyclically Adjusted Book per Share: $10.36
  • GF Value™: $61.78 vs. price of $67.50 (9.3% above fair value)
  • GF Score™: 66/100 with 5 warning signs

No single metric tells the full story. See the ANAB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


AnaptysBio Business Description

Other Exchanges 0HFQ:UKAN6:Germany
Address 10770 Wateridge Circle, Suite 210, San Diego, CA, USA, 92121
AnaptysBio Inc is a clinical-stage biotechnology company. The company is focused on developing antibody product candidates for unmet medical needs in inflammation and immuno-oncology. The company is developing immune cell modulating antibodies, including two wholly owned checkpoint agonists in clinical-stage development, for autoimmune and inflammatory diseases; rosnilimab, PD-1 agonist in a Phase 2b trial for the treatment of moderate-to-severe rheumatoid arthritis (RA) and a Phase 2 trial for the treatment of moderate-to-severe ulcerative colitis (UC); and ANB032, BTLA agonist, in a Phase 2b trial for the treatment of moderate-to-severe atopic dermatitis (AD).
66GF Score

Get the complete analysis for ANAB

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$67.50
Price
$61.78
GF Value