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EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Iovance Biotherapeutics's Enterprise Value is $1,551.6 Mil.
Iovance Biotherapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 was $-270.8 Mil. Therefore, Iovance Biotherapeutics's EV-to-OCF for today is -5.73.
The historical rank and industry rank for Iovance Biotherapeutics's EV-to-OCF or its related term are showing as below:
IOVA'
s EV-to-OCF Range Over the Past 10 Years
Min: -11.32 Med: -4.34 Max: -0.69
Current: -5.73
During the past 13 years, the highest EV-to-OCF of Iovance Biotherapeutics was -0.69. The lowest was -11.32. And the median was -4.34.
IOVA's EV-to-OCF is ranked better than 62.98% of 1410
companies
in the Biotechnology industry
Industry Median: -3.345
vs IOVA: -5.73
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Iovance Biotherapeutics's PE Ratio (TTM) for today is calculated as:
Iovance Biotherapeutics's share price for today is $4.07.
Iovance Biotherapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.950.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Iovance Biotherapeutics's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Iovance Biotherapeutics EV-to-OCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Iovance Biotherapeutics's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where Iovance Biotherapeutics's EV-to-OCF falls into.
Iovance Biotherapeutics's current Enterprise Value is $1,551.6 Mil.
Iovance Biotherapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-270.8 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Iovance Biotherapeutics (IOVA) has a EV-to-OCF of -5.73 as of Aug. 01, 2026. According to the industry distribution chart, Iovance Biotherapeutics ranks #522 out of 1410 companies in the Biotechnology industry, placing it in the top 37%.
Is Iovance Biotherapeutics' EV-to-OCF too high?
Iovance Biotherapeutics' current EV-to-OCF is -5.73. Based on the distribution chart, Iovance Biotherapeutics ranks #522 out of 1410 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Iovance Biotherapeutics has a GF Score™ of 31/100, reflecting its overall financial health beyond just this single metric.
How does Iovance Biotherapeutics' EV-to-OCF compare to SLS and NUVB?
According to the Biotechnology industry distribution chart, Iovance Biotherapeutics ranks #522 out of 1410 companies for EV-to-OCF. This puts Iovance Biotherapeutics in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Iovance Biotherapeutics's current EV-to-OCF is -5.73. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Iovance Biotherapeutics stock overvalued right now?
Iovance Biotherapeutics (IOVA) has a current EV-to-OCF of -5.73. The current EV-to-OCF is -5.73. Iovance Biotherapeutics' overall GF Score™ is 31/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Iovance Biotherapeutics (IOVA), the current EV-to-OCF is -5.73 as of Aug. 01, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Iovance Biotherapeutics Inc is a clinical-stage biopharmaceutical company, pioneering a transformational approach to treating cancer by harnessing the human immune system's ability to recognize and destroy diverse cancer cells using therapies personalized for each patient. The company is preparing for potential U.S. regulatory approvals and commercialization of the first autologous T-cell therapy to address a solid tumor cancer. It operates in one segment, focusing on innovating, developing, and commercializing therapies using its autologous TIL cell therapies for patients with solid tumor cancers. Geographically, the company operates in United States and Rest of the World.
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