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EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Taysha Gene Therapies's Enterprise Value is $1,236.99 Mil.
Taysha Gene Therapies's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 was $-132.19 Mil. Therefore, Taysha Gene Therapies's EV-to-OCF for today is -9.36.
The historical rank and industry rank for Taysha Gene Therapies's EV-to-OCF or its related term are showing as below:
TSHA'
s EV-to-OCF Range Over the Past 10 Years
Min: -21.63 Med: -5.61 Max: -0.12
Current: -9.36
During the past 7 years, the highest EV-to-OCF of Taysha Gene Therapies was -0.12. The lowest was -21.63. And the median was -5.61.
TSHA's EV-to-OCF is ranked better than 69.04% of 1405
companies
in the Biotechnology industry
Industry Median: -3.4
vs TSHA: -9.36
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Taysha Gene Therapies's PE Ratio (TTM) for today is calculated as:
Taysha Gene Therapies's share price for today is $5.02.
Taysha Gene Therapies's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.420.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Taysha Gene Therapies's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Taysha Gene Therapies EV-to-OCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Taysha Gene Therapies's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where Taysha Gene Therapies's EV-to-OCF falls into.
Taysha Gene Therapies's current Enterprise Value is $1,236.99 Mil.
Taysha Gene Therapies's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-132.19 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Taysha Gene Therapies (TSHA) has a EV-to-OCF of -9.36 as of Sep. 12, 2026. According to the industry distribution chart, Taysha Gene Therapies ranks #435 out of 1405 companies in the Biotechnology industry, placing it in the top 31%.
Is Taysha Gene Therapies' EV-to-OCF too high?
Taysha Gene Therapies' current EV-to-OCF is -9.36. Based on the distribution chart, Taysha Gene Therapies ranks #435 out of 1405 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Taysha Gene Therapies has a GF Score™ of 33/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Taysha Gene Therapies' EV-to-OCF compare to KARD and GHRS?
According to the Biotechnology industry distribution chart, Taysha Gene Therapies ranks #435 out of 1405 companies for EV-to-OCF. This puts Taysha Gene Therapies in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Taysha Gene Therapies's current EV-to-OCF is -9.36. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Taysha Gene Therapies stock overvalued right now?
Based on GuruFocus' analysis, Taysha Gene Therapies (TSHA) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.53, compared to a current price of $5.02 — trading 847.2% above its estimated fair value. The current EV-to-OCF is -9.36. Taysha Gene Therapies' overall GF Score™ is 33/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Taysha Gene Therapies (TSHA), the current EV-to-OCF is -9.36 as of Sep. 12, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Taysha Gene Therapies (TSHA) Overvalued in 2026?
Based on GuruFocus' analysis, Taysha Gene Therapies stock appears to be overvalued.
The current stock price of $5.02 is trading 847.2% above its estimated GF Value™ of $0.53.
GuruFocus considers Taysha Gene Therapies to be Significantly Overvalued.
Key valuation signals for TSHA:
EV-to-OCF: -9.36
GF Value™: $0.53 vs. price of $5.02 (847.2% above fair value)
No single metric tells the full story. See the TSHA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Taysha Gene Therapies Inc is a clinical-stage biotechnology company focused on advancing AAV-based gene therapies for the treatment of severe monogenic diseases of the central nervous system, or CNS. The company's clinical program TSHA-102 is in development for the treatment of Rett syndrome, a rare neurodevelopmental disorder with no approved disease-modifying therapies that address the genetic root cause of the disease. The Company views its operations and manages its business as a single operating segment, the gene therapy segment, which is the business of developing AAV-based gene therapies for the treatment of rare monogenic diseases of the central nervous system.
33GF Score
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EV-to-OCF is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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