TSHA (Taysha Gene Therapies) Beneish M-Score: -3.36 (As of Sep. 12, 2026)

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TSHA Taysha Gene Therapies Inc TSHA
33 GF Score
Price $5.02
GF Value $0.53
Valuation Significantly Overvalued
! 2 Warning Signs
View Full Analysis

What is Taysha Gene Therapies Beneish M-Score?

Taysha Gene Therapies TSHA -2.71% 33 Beneish M-Score is -3.36 as of Sep. 12, 2026. GuruFocus rates TSHA with a GF Score™ of 33/100 and a GF Value™ of $0.53 (Significantly Overvalued). The stock has 2 warning signs investors should review. Among 832 Biotechnology companies, Taysha Gene Therapies ranks better than 81.85% on this metric.

The zones of discrimination for M-Score is as such:

An M-Score of equal or less than -1.78 suggests that the company is unlikely to be a manipulator.
An M-Score of greater than -1.78 signals that the company is likely to be a manipulator.

Good Sign:

Beneish M-Score -3.36 no higher than -1.78, which implies that the company is unlikely to be a manipulator.

The historical rank and industry rank for Taysha Gene Therapies's Beneish M-Score or its related term are showing as below:

TSHA' s Beneish M-Score Range Over the Past 10 Years
Min: -3.36   Med: -2.66   Max: 2.17
Current: -3.36

During the past 7 years, the highest Beneish M-Score of Taysha Gene Therapies was 2.17. The lowest was -3.36. And the median was -2.66.


Taysha Gene Therapies Beneish M-Score Historical Data

* Premium members only.

The historical data trend for Taysha Gene Therapies's Beneish M-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Taysha Gene Therapies Beneish M-Score Chart

Taysha Gene Therapies Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Beneish M-Score
Get a 7-Day Free Trial 0.00 0.00 2.17 -2.98 -2.47

Taysha Gene Therapies Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Beneish M-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2.97 -3.12 -2.47 -2.66 -3.36

TSHA vs KARD, GHRS, VIR: Beneish M-Score Comparison

For the Biotechnology subindustry, Taysha Gene Therapies's Beneish M-Score, along with its competitors' market caps and Beneish M-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Taysha Gene Therapies Beneish M-Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Taysha Gene Therapies's Beneish M-Score distribution charts can be found below:

* The bar in red indicates where Taysha Gene Therapies's Beneish M-Score falls into.


TSHA
33GF Score
Taysha Gene Therapies Inc TSHA
Beneish M-Score is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Taysha Gene Therapies Beneish M-Score Calculation

The M-score was created by Professor Messod Beneish. Instead of measuring the bankruptcy risk (Altman Z-Score) or business trend (Piotroski F-Score), M-score can be used to detect the risk of earnings manipulation. This is the original research paper on M-score.

The M-Score Variables:

The M-score of Taysha Gene Therapies for today is based on a combination of the following eight different indices:

M=-4.84+0.92 * DSRI+0.528 * GMI+0.404 * AQI+0.892 * SGI+0.115 * DEPI
=-4.84+0.92 * 1+0.528 * 1+0.404 * 0.0819+0.892 * 0.6773+0.115 * 0.6162
-0.172 * SGAI+4.679 * TATA-0.327 * LVGI
-0.172 * 1.8373+4.679 * -0.028682-0.327 * 0.6942
=-3.36

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Jun26) TTM:Last Year (Jun25) TTM:
Total Receivables was $0.00 Mil.
Revenue was 0 + 0 + 5.485 + 0 = $5.49 Mil.
Gross Profit was 0 + 0 + 5.485 + 0 = $5.49 Mil.
Total Current Assets was $461.43 Mil.
Total Assets was $470.43 Mil.
Property, Plant and Equipment(Net PPE) was $8.73 Mil.
Depreciation, Depletion and Amortization(DDA) was $1.17 Mil.
Selling, General, & Admin. Expense(SGA) was $38.94 Mil.
Total Current Liabilities was $25.98 Mil.
Long-Term Debt & Capital Lease Obligation was $55.55 Mil.
Net Income was -46.639 + -42.41 + -27.851 + -32.733 = $-149.63 Mil.
Non Operating Income was 1.824 + -1.501 + -2.409 + -1.863 = $-3.95 Mil.
Cash Flow from Operations was -40.425 + -40.878 + -26.722 + -24.166 = $-132.19 Mil.
Total Receivables was $0.00 Mil.
Revenue was 1.986 + 2.302 + 2.022 + 1.788 = $8.10 Mil.
Gross Profit was 1.986 + 2.302 + 2.022 + 1.788 = $8.10 Mil.
Total Current Assets was $316.26 Mil.
Total Assets was $333.33 Mil.
Property, Plant and Equipment(Net PPE) was $14.73 Mil.
Depreciation, Depletion and Amortization(DDA) was $1.16 Mil.
Selling, General, & Admin. Expense(SGA) was $31.29 Mil.
Total Current Liabilities was $25.35 Mil.
Long-Term Debt & Capital Lease Obligation was $57.86 Mil.




1. DSRI = Days Sales in Receivables Index

Measured as the ratio of Revenue in Total Receivables in year t to year t-1.

A large increase in DSR could be indicative of revenue inflation.

DSRI=(Receivables_t / Revenue_t) / (Receivables_t-1 / Revenue_t-1)
=(0 / 5.485) / (0 / 8.098)
=0 / 0
=1

2. GMI = Gross Margin Index

Measured as the ratio of gross margin in year t-1 to gross margin in year t.

Gross margin has deteriorated when this index is above 1. A firm with poorer prospects is more likely to manipulate earnings.

GMI=GrossMargin_t-1 / GrossMargin_t
=(GrossProfit_t-1 / Revenue_t-1) / (GrossProfit_t / Revenue_t)
=(8.098 / 8.098) / (5.485 / 5.485)
=1 / 1
=1

3. AQI = Asset Quality Index

AQI is the ratio of asset quality in year t to year t-1.

Asset quality is measured as the ratio of non-current assets other than Property, Plant and Equipment to Total Assets.

AQI=(1 - (CurrentAssets_t + PPE_t) / TotalAssets_t) / (1 - (CurrentAssets_t-1 + PPE_t-1) / TotalAssets_t-1)
=(1 - (461.434 + 8.729) / 470.433) / (1 - (316.264 + 14.73) / 333.331)
=0.000574 / 0.007011
=0.0819

4. SGI = Sales Growth Index

Ratio of Revenue in year t to sales in year t-1.

Sales growth is not itself a measure of manipulation. However, growth companies are likely to find themselves under pressure to manipulate in order to keep up appearances.

SGI=Sales_t / Sales_t-1
=Revenue_t / Revenue_t-1
=5.485 / 8.098
=0.6773

5. DEPI = Depreciation Index

Measured as the ratio of the rate of Depreciation, Depletion and Amortization in year t-1 to the corresponding rate in year t.

DEPI greater than 1 indicates that assets are being depreciated at a slower rate. This suggests that the firm might be revising useful asset life assumptions upwards, or adopting a new method that is income friendly.

DEPI=(Depreciation_t-1 / (Depreciaton_t-1 + PPE_t-1)) / (Depreciation_t / (Depreciaton_t + PPE_t))
=(1.158 / (1.158 + 14.73)) / (1.171 / (1.171 + 8.729))
=0.072885 / 0.118283
=0.6162

Note: If the Depreciation, Depletion and Amortization data is not available, we assume that the depreciation rate is constant and set the Depreciation Index to 1.

6. SGAI = Sales, General and Administrative expenses Index

The ratio of Selling, General, & Admin. Expense(SGA) to Sales in year t relative to year t-1.

SGA expenses index > 1 means that the company is becoming less efficient in generate sales.

SGAI=(SGA_t / Sales_t) / (SGA_t-1 /Sales_t-1)
=(38.935 / 5.485) / (31.287 / 8.098)
=7.09845 / 3.863547
=1.8373

7. LVGI = Leverage Index

The ratio of total debt to Total Assets in year t relative to yeat t-1.

An LVGI > 1 indicates an increase in leverage

LVGI=((LTD_t + CurrentLiabilities_t) / TotalAssets_t) / ((LTD_t-1 + CurrentLiabilities_t-1) / TotalAssets_t-1)
=((55.551 + 25.975) / 470.433) / ((57.859 + 25.349) / 333.331)
=0.1733 / 0.249626
=0.6942

8. TATA = Total Accruals to Total Assets

Total accruals calculated as the change in working capital accounts other than cash less depreciation.

TATA=(IncomefromContinuingOperations_t - CashFlowsfromOperations_t) / TotalAssets_t
=(NetIncome_t - NonOperatingIncome_t - CashFlowsfromOperations_t) / TotalAssets_t
=(-149.633 - -3.949 - -132.191) / 470.433
=-0.028682

An M-Score of equal or less than -1.78 suggests that the company is unlikely to be a manipulator. An M-Score of greater than -1.78 signals that the company is likely to be a manipulator.

Taysha Gene Therapies has a M-score of -3.36 suggests that the company is unlikely to be a manipulator.

Frequently Asked Questions Learn more about Beneish M-Score →
What does a Beneish M-Score of -3.36 mean?
Taysha Gene Therapies (TSHA) has a Beneish M-Score of -3.36 as of Sep. 12, 2026. The Beneish M-score measures the likelihood of earnings manipulation. View historical data on Taysha Gene Therapies and its competitors. According to the industry distribution chart, Taysha Gene Therapies ranks #151 out of 832 companies in the Biotechnology industry, placing it in the top 18.1%.
Is Taysha Gene Therapies' Beneish M-Score too high?
Taysha Gene Therapies' current Beneish M-Score is -3.36. Based on the distribution chart, Taysha Gene Therapies ranks #151 out of 832 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Taysha Gene Therapies has a GF Score™ of 33/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Taysha Gene Therapies' Beneish M-Score compare to KARD and GHRS?
According to the Biotechnology industry distribution chart, Taysha Gene Therapies ranks #151 out of 832 companies for Beneish M-Score. This places Taysha Gene Therapies in the top 18% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Beneish M-Score for a Biotechnology company?
A good Beneish M-Score depends on the Biotechnology industry context. However, Beneish M-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Beneish M-Score mean?
A high Beneish M-Score can signal that a stock is expensive relative to its fundamentals. The Beneish M-score measures the likelihood of earnings manipulation. View historical data on Taysha Gene Therapies and its competitors. Taysha Gene Therapies's current Beneish M-Score is -3.36. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Taysha Gene Therapies stock overvalued right now?
Based on GuruFocus' analysis, Taysha Gene Therapies (TSHA) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.53, compared to a current price of $5.02 — trading 847.2% above its estimated fair value. The current Beneish M-Score is -3.36. Taysha Gene Therapies' overall GF Score™ is 33/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Beneish M-Score calculated?
Beneish M-Score is calculated from a company's financial statements. For Taysha Gene Therapies (TSHA), the current Beneish M-Score is -3.36 as of Sep. 12, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Taysha Gene Therapies (TSHA) Overvalued in 2026?

Based on GuruFocus' analysis, Taysha Gene Therapies stock appears to be overvalued. The current stock price of $5.02 is trading 847.2% above its estimated GF Value™ of $0.53. GuruFocus considers Taysha Gene Therapies to be Significantly Overvalued.

Key valuation signals for TSHA:

  • Beneish M-Score: -3.36
  • GF Value™: $0.53 vs. price of $5.02 (847.2% above fair value)
  • GF Score™: 33/100 with 2 warning signs

No single metric tells the full story. See the TSHA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Taysha Gene Therapies Business Description

Address 3000 Pegasus Park Drive, Suite 1430, Dallas, TX, USA, 75247
Taysha Gene Therapies Inc is a clinical-stage biotechnology company focused on advancing AAV-based gene therapies for the treatment of severe monogenic diseases of the central nervous system, or CNS. The company's clinical program TSHA-102 is in development for the treatment of Rett syndrome, a rare neurodevelopmental disorder with no approved disease-modifying therapies that address the genetic root cause of the disease. The Company views its operations and manages its business as a single operating segment, the gene therapy segment, which is the business of developing AAV-based gene therapies for the treatment of rare monogenic diseases of the central nervous system.
33GF Score

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Beneish M-Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$5.02
Price
$0.53
GF Value