Heartseed (TSE:219A) Enterprise Value: 円27,785 Mil (As of Jul. 21, 2026) ***

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TSE:219A Heartseed Inc TSE:219A
11 GF Score
Price 円1,600.00
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What is Heartseed Enterprise Value?

Heartseed TSE:219A +7.02% 11 Enterprise Value is 円27,785 Mil as of Jul. 21, 2026. GuruFocus rates TSE:219A with a GF Score™ of 11/100.

Think of Enterprise Value as the theoretical takeover price. It is more comprehensive than market capitalization (Market Cap), which only includes common equity. Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Heartseed's Enterprise Value is 円27,785 Mil. Heartseed's EBIT for the trailing twelve months (TTM) ended in Oct. 2025 was 円-613 Mil. Therefore, Heartseed's EV-to-EBIT ratio for today is -45.34.

EV-to-EBITDA is calculated as Enterprise Value divided by its EBITDA. As of today, Heartseed's Enterprise Value is 円27,785 Mil. Heartseed's EBITDA for the trailing twelve months (TTM) ended in Oct. 2025 was 円-580 Mil. Therefore, Heartseed's EV-to-EBITDA ratio for today is -47.90.

EV-to-Revenue is calculated as Enterprise Value divided by its Revenue. As of today, Heartseed's Enterprise Value is 円27,785 Mil. Heartseed's Revenue for the trailing twelve months (TTM) ended in Oct. 2025 was 円1,573 Mil. Therefore, Heartseed's EV-to-Revenue ratio for today is 17.66.

EV-to-OCF is calculated as Enterprise Value divided by its Cash Flow from Operations. As of today, Heartseed's Enterprise Value is 円27,785 Mil. Heartseed's Cash Flow from Operations for the trailing twelve months (TTM) ended in Oct. 2025 was 円0 Mil. Therefore, Heartseed's EV-to-OCF ratio for today is .

EV-to-FCF is calculated as Enterprise Value divided by its Free Cash Flow. As of today, Heartseed's Enterprise Value is 円27,785 Mil. Heartseed's Free Cash Flow for the trailing twelve months (TTM) ended in Oct. 2025 was 円0 Mil. Therefore, Heartseed's EV-to-FCF ratio for today is .

*** Please note that the current Enterprise Value is calculated using the current market capitalization and the most recently available financial data. If key financial fields—Long-Term Debt & Capital Lease Obligation and Short-Term Debt & Capital Lease Obligation—are recorded as null in the latest reporting period, our data vendor will default to using data from the prior period with valid entries.


Heartseed  (TSE:219A) Enterprise Value Explanation

When an investor buy a company, the investor needs to pay not only the common shares, he/she also needs to pay the shareholders of Preferred Stocks. He also assumes the debt of the company, and receives the cash on the company's balance sheet.

If a company has more cash than debt, the investor actually pays less than the Market Cap because he immediately owns the cash once the transaction goes through.

The market value of Preferred Stock needs to be added to the market value of common stocks in the calculation of Enterprise Value.

For the companies with the same Market Cap, the smaller the Enterprise Value is, the cheaper the company is.

Enterprise Value can be negative when the company's net cash is more than its Market Cap. In this case the investor is basically getting the company for free and get paid for that.

1. EV-to-EBIT is calculated as Enterprise Value divided by its EBIT.

Heartseed's EV-to-EBIT for today is

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=27785.393/-612.764
=-45.34

Heartseed's current Enterprise Value is 円27,785 Mil.
Heartseed's EBIT for the trailing twelve months (TTM) ended in Oct. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-613 Mil.

2. EV-to-EBITDA is calculated as Enterprise Value divided by its EBITDA.

Heartseed's EV-to-EBITDA for today is:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA(TTM)
=27785.393/-580.024
=-47.90

Heartseed's current Enterprise Value is 円27,785 Mil.
Heartseed's EBITDA for the trailing twelve months (TTM) ended in Oct. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-580 Mil.

3. EV-to-Revenue is calculated as Enterprise Value divided by its Revenue.

Heartseed's EV-to-Revenue for today is:

EV-to-Revenue=Enterprise Value (Today)/Revenue (TTM)
=27785.393/1573.02
=17.66

Heartseed's current Enterprise Value is 円27,785 Mil.
Heartseed's Revenue for the trailing twelve months (TTM) ended in Oct. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was 円1,573 Mil.

4. EV-to-OCF is calculated as Enterprise Value divided by its Cash Flow from Operations.

Heartseed's EV-to-OCF for today is:


Heartseed's current Enterprise Value is 円27,785 Mil.
Heartseed's Cash Flow from Operations for the trailing twelve months (TTM) ended in Oct. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was 円0 Mil.

5. EV-to-FCF is calculated as Enterprise Value divided by its Free Cash Flow.

Heartseed's EV-to-FCF for today is:

EV-to-FCF=Enterprise Value (Today)/Free Cash Flow (TTM)
=27785.393/0
=

Heartseed's current Enterprise Value is 円27,785 Mil.
Heartseed's Free Cash Flow for the trailing twelve months (TTM) ended in Oct. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was 円0 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Heartseed Enterprise Value Related Terms


Heartseed Enterprise Value Historical Data

* Premium members only.

The historical data trend for Heartseed's Enterprise Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Heartseed Enterprise Value Chart

Heartseed Annual Data
Trend Oct22 Oct23 Oct24 Oct25
Enterprise Value
0.00 0.00 25,334.28 32,695.71

Heartseed Quarterly Data
Oct22 Oct23 Apr24 Jul24 Oct24 Apr25 Jul25 Oct25 Mar26
Enterprise Value Get a 7-Day Free Trial Premium Member Only 25,334.28 50,778.05 76,913.84 32,695.71 33,160.48

TSE:219A vs VRTX, REGN, ALNY: Enterprise Value Comparison

For the Biotechnology subindustry, Heartseed's Enterprise Value, along with its competitors' market caps and Enterprise Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Heartseed Enterprise Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Heartseed's Enterprise Value distribution charts can be found below:

* The bar in red indicates where Heartseed's Enterprise Value falls into.


TSE:219A
11GF Score
Heartseed Inc TSE:219A
Enterprise Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Heartseed Enterprise Value Calculation

Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.

Heartseed's Enterprise Value for the fiscal year that ended in Oct. 2025 is calculated as

Heartseed's Enterprise Value for the quarter that ended in Oct. 2025 is calculated as

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Enterprise Value →
What does a Enterprise Value of 円27,785 Mil mean?
Heartseed (TSE:219A) has a Enterprise Value of 円27,785 Mil as of Jul. 21, 2026. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on Heartseed and its competitors.
Is Heartseed's Enterprise Value too high?
Heartseed's current Enterprise Value is 円27,785 Mil. Overall, Heartseed has a GF Score™ of 11/100, reflecting its overall financial health beyond just this single metric.
How does Heartseed's Enterprise Value compare to VRTX and REGN?
Heartseed's Enterprise Value of 円27,785 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Enterprise Value for a Biotechnology company?
A good Enterprise Value depends on the Biotechnology industry context. However, Enterprise Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Enterprise Value mean?
A high Enterprise Value can signal that a stock is expensive relative to its fundamentals. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on Heartseed and its competitors. Heartseed's current Enterprise Value is 円27,785 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Heartseed stock overvalued right now?
Heartseed (TSE:219A) has a current Enterprise Value of 円27,785 Mil. The current Enterprise Value is 円27,785 Mil. Heartseed's overall GF Score™ is 11/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Enterprise Value calculated?
Enterprise Value is calculated from a company's financial statements. For Heartseed (TSE:219A), the current Enterprise Value is 円27,785 Mil as of Jul. 21, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Heartseed Business Description

Address 1-2-3 Shibaura, Minato-ku, Tokyo, JPN, 105-0023
Heartseed Inc is a Japanese biotechnology company focused on developing and commercializing regenerative medicine treatments for severe heart failure. The company's product candidate, HS-001, involves transplanting clusters of purified heart muscle cells derived from iPSCs to the patient's heart to treat heart failure, especially Heart Failure with reduced Left Ventricular Ejection Fraction (HFrEF), including conditions such as Dilated Cardiomyopathy, Old Myocardial Infarction, and Dilated phase of Hypertrophic Cardiomyopathy.
11GF Score

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Enterprise Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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