Heartseed (TSE:219A) Return-on-Tangible-Asset: -27.08% (As of Jun. 2026)

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Director of Data and Quant Analytics at GuruFocus
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Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

TSE:219A Heartseed Inc TSE:219A
13 GF Score
Price 円2,385.00
! 2 Warning Signs
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What is Heartseed Return-on-Tangible-Asset?

Heartseed TSE:219A +6.28% 13 Return-on-Tangible-Asset is -27.08% as of Jun. 2026. GuruFocus rates TSE:219A with a GF Score™ of 13/100. The stock has 2 warning signs investors should review. Among 1,415 Biotechnology companies, Heartseed ranks better than 67.14% on this metric.

Return-on-Tangible-Asset is calculated as Net Income divided by its average total tangible assets. Total tangible assets equals to Total Assets minus Intangible Assets. Heartseed's annualized Net Income for the quarter that ended in Jun. 2026 was 円-1,985 Mil. Heartseed's average total tangible assets for the quarter that ended in Jun. 2026 was 円7,328 Mil. Therefore, Heartseed's annualized Return-on-Tangible-Asset for the quarter that ended in Jun. 2026 was -27.08%.

The historical rank and industry rank for Heartseed's Return-on-Tangible-Asset or its related term are showing as below:

TSE:219A' s Return-on-Tangible-Asset Range Over the Past 10 Years
Min: -28.62   Med: -27.66   Max: -12.71
Current: -14.26

During the past 3 years, Heartseed's highest Return-on-Tangible-Asset was -12.71%. The lowest was -28.62%. And the median was -27.66%.

TSE:219A's Return-on-Tangible-Asset is ranked better than
67.14% of 1415 companies
in the Biotechnology industry
Industry Median: -35.77 vs TSE:219A: -14.26

Heartseed  (TSE:219A) Return-on-Tangible-Asset Explanation

Return-on-Tangible-Asset measures the rate of return on the average total tangible assets (total assets minus intangible assets). Tangible means physical in nature. Intangible Assets are assets that are not physical in nature, and typically "derive their value from legal or intellectual rights." Return-on-Tangible-Asset measures a firm's efficiency at generating profits from its tangible assets. It shows how well a company uses what it has to generate earnings. Return-on-Tangible-Assets can vary drastically across industries. Therefore, Return-on-Tangible-Asset should not be used to compare companies in different industries.


Be Aware

Like ROE and ROA, Return-on-Tangible-Asset is calculated with only 12 months data. Fluctuations in the company’s earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. Return-on-Tangible-Asset can be affected by events such as stock buyback or issuance, and by a company’s tax rate and its interest payment. Return-on-Tangible-Asset may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high Return-on-Tangible-Asset may indicate vulnerability in the durability of the competitive advantage.


Heartseed Return-on-Tangible-Asset Related Terms


Heartseed Return-on-Tangible-Asset Historical Data

* Premium members only.

The historical data trend for Heartseed's Return-on-Tangible-Asset can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Heartseed Return-on-Tangible-Asset Chart

Heartseed Annual Data
Trend Oct22 Oct23 Oct24
Return-on-Tangible-Asset
-28.62 -27.66 -12.71

Heartseed Quarterly Data
Oct22 Oct23 Apr24 Jul24 Oct24 Apr25 Jul25 Oct25 Mar26 Jun26
Return-on-Tangible-Asset Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 -23.49 -2.75 -3.04 -27.08

TSE:219A vs VRTX, REGN, RVMD: Return-on-Tangible-Asset Comparison

For the Biotechnology subindustry, Heartseed's Return-on-Tangible-Asset, along with its competitors' market caps and Return-on-Tangible-Asset data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Heartseed Return-on-Tangible-Asset vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Heartseed's Return-on-Tangible-Asset distribution charts can be found below:

* The bar in red indicates where Heartseed's Return-on-Tangible-Asset falls into.


TSE:219A
13GF Score
Heartseed Inc TSE:219A
Return-on-Tangible-Asset is just one metric. See GF Score™, valuation, warning signs, and more.
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Heartseed Return-on-Tangible-Asset Calculation

Heartseed's annualized Return-on-Tangible-Asset for the fiscal year that ended in Oct. 2024 is calculated as:

Return-on-Tangible-Asset=Net Income/( (Total Tangible Assets+Total Tangible Assets)/ count )
(A: Oct. 2024 )  (A: Oct. 2023 )(A: Oct. 2024 )
=Net Income/( (Total Assets - Intangible Assets+Total Assets - Intangible Assets)/ count )
(A: Oct. 2024 )  (A: Oct. 2023 )(A: Oct. 2024 )
=-812.725/( (5719.751+7067.594)/ 2 )
=-812.725/6393.6725
=-12.71 %

Heartseed's annualized Return-on-Tangible-Asset for the quarter that ended in Jun. 2026 is calculated as:

Return-on-Tangible-Asset=Net Income/( (Total Tangible Assets+Total Tangible Assets)/ count )
(Q: Jun. 2026 )  (Q: Mar. 2026 )(Q: Jun. 2026 )
=Net Income/( (Total Assets - Intangible Assets+Total Assets - Intangible Assets)/ count )
(Q: Jun. 2026 )  (Q: Mar. 2026 )(Q: Jun. 2026 )
=-1984.588/( (7613.354+7042.512)/ 2 )
=-1984.588/7327.933
=-27.08 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Asset, the net income of the last fiscal year and the average total tangible assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Jun. 2026) net income data.

What does a Return-on-Tangible-Asset of -27.08% mean?
Heartseed (TSE:219A) has a Return-on-Tangible-Asset of -27.08% as of Jun. 2026. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on Heartseed and its competitors. According to the industry distribution chart, Heartseed ranks #465 out of 1415 companies in the Biotechnology industry, placing it in the top 32.9%.
Is Heartseed's Return-on-Tangible-Asset too high?
Heartseed's current Return-on-Tangible-Asset is -27.08%. Based on the distribution chart, Heartseed ranks #465 out of 1415 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Heartseed has a GF Score™ of 13/100, reflecting its overall financial health beyond just this single metric.
How does Heartseed's Return-on-Tangible-Asset compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Heartseed ranks #465 out of 1415 companies for Return-on-Tangible-Asset. This puts Heartseed in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Asset for a Biotechnology company?
A good Return-on-Tangible-Asset depends on the Biotechnology industry context. However, Return-on-Tangible-Asset should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Asset mean?
A high Return-on-Tangible-Asset can signal that a stock is expensive relative to its fundamentals. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on Heartseed and its competitors. Heartseed's current Return-on-Tangible-Asset is -27.08%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Heartseed stock overvalued right now?
Heartseed (TSE:219A) has a current Return-on-Tangible-Asset of -27.08%. The current Return-on-Tangible-Asset is -27.08%. Heartseed's overall GF Score™ is 13/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Asset calculated?
Return-on-Tangible-Asset is calculated from a company's financial statements. For Heartseed (TSE:219A), the current Return-on-Tangible-Asset is -27.08% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Heartseed Business Description

Address 1-2-3 Shibaura, Minato-ku, Tokyo, JPN, 105-0023
Heartseed Inc is a Japanese biotechnology company focused on developing and commercializing regenerative medicine treatments for severe heart failure. The company's product candidate, HS-001, involves transplanting clusters of purified heart muscle cells derived from iPSCs to the patient's heart to treat heart failure, especially Heart Failure with reduced Left Ventricular Ejection Fraction (HFrEF), including conditions such as Dilated Cardiomyopathy, Old Myocardial Infarction, and Dilated phase of Hypertrophic Cardiomyopathy.
13GF Score

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Return-on-Tangible-Asset is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円2,385.00
Price