Heartseed (TSE:219A) Net Margin %: -4.77% (As of Oct. 2025)

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TSE:219A Heartseed Inc TSE:219A
11 GF Score
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What is Heartseed Net Margin %?

Heartseed TSE:219A -4.41% 11 Net Margin % is -4.77% as of Oct. 2025. GuruFocus rates TSE:219A with a GF Score™ of 11/100. Among 942 Biotechnology companies, Heartseed ranks better than 58.6% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Heartseed's Net Income for the three months ended in Oct. 2025 was 円-53 Mil. Heartseed's Revenue for the three months ended in Oct. 2025 was 円1,107 Mil. Therefore, Heartseed's net margin for the quarter that ended in Oct. 2025 was -4.77%.

The historical rank and industry rank for Heartseed's Net Margin % or its related term are showing as below:

TSE:219A' s Net Margin % Range Over the Past 10 Years
Min: -427.44   Med: -188.06   Max: 6.3
Current: -36.53

TSE:219A's Net Margin % is ranked better than
58.6% of 942 companies
in the Biotechnology industry
Industry Median: -88.295 vs TSE:219A: -36.53

Heartseed  (TSE:219A) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.

Heartseed Net Margin % Related Terms

Heartseed Net Margin % Historical Data

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The historical data trend for Heartseed's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Heartseed Net Margin % Chart

Heartseed Annual Data
Trend Oct22 Oct23 Oct24 Oct25
Net Margin %
-283.08 -427.44 -93.03 6.30

Heartseed Quarterly Data
Oct22 Oct23 Apr24 Jul24 Oct24 Apr25 Jul25 Oct25 Mar26
Net Margin % Get a 7-Day Free Trial Premium Member Only 38.29 0.00 0.00 -4.77 -12.48

TSE:219A vs VRTX, REGN, ALNY: Net Margin % Comparison

For the Biotechnology subindustry, Heartseed's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Heartseed Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Heartseed's Net Margin % distribution charts can be found below:

* The bar in red indicates where Heartseed's Net Margin % falls into.


TSE:219A
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Heartseed Inc TSE:219A
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Heartseed Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Heartseed's Net Margin for the fiscal year that ended in Oct. 2025 is calculated as

Net Margin=Net Income (A: Oct. 2025 )/Revenue (A: Oct. 2025 )
=190.608/3026.5
=6.30 %

Heartseed's Net Margin for the quarter that ended in Oct. 2025 is calculated as

Net Margin=Net Income (Q: Oct. 2025 )/Revenue (Q: Oct. 2025 )
=-52.842/1107.15
=-4.77 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -4.77% mean?
Heartseed (TSE:219A) has a Net Margin % of -4.77% as of Oct. 2025. Net margin is the ratio of total net income to net sales. View historical data on Heartseed and its competitors. According to the industry distribution chart, Heartseed ranks #390 out of 942 companies in the Biotechnology industry, placing it in the top 41.4%.
Is Heartseed's Net Margin % too high?
Heartseed's current Net Margin % is -4.77%. Based on the distribution chart, Heartseed ranks #390 out of 942 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Heartseed has a GF Score™ of 11/100, reflecting its overall financial health beyond just this single metric.
How does Heartseed's Net Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Heartseed ranks #390 out of 942 companies for Net Margin %. This puts Heartseed in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Heartseed and its competitors. Heartseed's current Net Margin % is -4.77%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Heartseed stock overvalued right now?
Heartseed (TSE:219A) has a current Net Margin % of -4.77%. The current Net Margin % is -4.77%. Heartseed's overall GF Score™ is 11/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Heartseed (TSE:219A), the current Net Margin % is -4.77% as of Oct. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Heartseed Business Description

Address 1-2-3 Shibaura, Minato-ku, Tokyo, JPN, 105-0023
Heartseed Inc is a Japanese biotechnology company focused on developing and commercializing regenerative medicine treatments for severe heart failure. The company's product candidate, HS-001, involves transplanting clusters of purified heart muscle cells derived from iPSCs to the patient's heart to treat heart failure, especially Heart Failure with reduced Left Ventricular Ejection Fraction (HFrEF), including conditions such as Dilated Cardiomyopathy, Old Myocardial Infarction, and Dilated phase of Hypertrophic Cardiomyopathy.
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Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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