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Iterum TherapeuticsITRMF +3.85% EV-to-FCF is -1.24 as of Jul. 17, 2026. The stock has 4 warning signs investors should review. Among 335 Biotechnology companies, Iterum Therapeutics ranks worse than 298507.16% on this metric.
EV-to-FCF is calculated as enterprise value divided by its free cash flow. As of today, Iterum Therapeutics's Enterprise Value is $24.17 Mil.
Iterum Therapeutics's Free Cash Flow for the trailing twelve months (TTM) ended in Sep. 2025 was $-19.53 Mil. Therefore, Iterum Therapeutics's EV-to-FCF for today is -1.24.
The historical rank and industry rank for Iterum Therapeutics's EV-to-FCF or its related term are showing as below:
ITRMF'
s EV-to-FCF Range Over the Past 10 Years
Min: -2.94 Med: -0.17 Max: 1.83
Current: -1.24
During the past 9 years, the highest EV-to-FCF of Iterum Therapeutics was 1.83. The lowest was -2.94. And the median was -0.17.
ITRMF's EV-to-FCF is ranked worse than 100% of 335
companies
in the Biotechnology industry
Industry Median: 15.51
vs ITRMF: -1.24
EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Iterum Therapeutics (OTCPK:ITRMF) EV-to-FCF Explanation
EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Iterum Therapeutics's PE Ratio (TTM) for today is calculated as:
Iterum Therapeutics's share price for today is $0.027.
Iterum Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Sep. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.750.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Free Cash Flow is an important financial metric because it represents the actual amount of cash at a company's disposal. Companies with a low EV-to-FCF ratio, combined with a strong balance sheet are generally considered as undervalued.
Iterum Therapeutics EV-to-FCF Related Terms
Iterum Therapeutics EV-to-FCF Historical Data
* Premium members only.
The historical data trend for Iterum Therapeutics's EV-to-FCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Iterum Therapeutics's EV-to-FCF, along with its competitors' market caps and EV-to-FCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Iterum Therapeutics EV-to-FCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Iterum Therapeutics's EV-to-FCF distribution charts can be found below:
* The bar in red indicates where Iterum Therapeutics's EV-to-FCF falls into.
Iterum Therapeutics's current Enterprise Value is $24.17 Mil.
Iterum Therapeutics's Free Cash Flow for the trailing twelve months (TTM) ended in Sep. 2025 adds up the quarterly data reported by the company within the most recent 12 months, which was $-19.53 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Iterum Therapeutics (ITRMF) has a EV-to-FCF of -1.24 as of Jul. 17, 2026. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on Iterum Therapeutics and its competitors. According to the industry distribution chart, Iterum Therapeutics ranks #999999 out of 335 companies in the Biotechnology industry.
Is Iterum Therapeutics' EV-to-FCF too high?
Iterum Therapeutics' current EV-to-FCF is -1.24. Based on the distribution chart, Iterum Therapeutics ranks #999999 out of 335 companies in the Biotechnology industry, which is in the bottom quartile relative to peers.
How does Iterum Therapeutics' EV-to-FCF compare to CASIF and OGEN?
According to the Biotechnology industry distribution chart, Iterum Therapeutics ranks #999999 out of 335 companies for EV-to-FCF. This places Iterum Therapeutics in the lower half of its industry. The industry median EV-to-FCF is 15.51. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-FCF for a Biotechnology company?
The median EV-to-FCF among Biotechnology companies is 15.51, based on 335 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-FCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-FCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-FCF mean?
A high EV-to-FCF can signal that a stock is expensive relative to its fundamentals. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on Iterum Therapeutics and its competitors. For the Biotechnology industry, the median EV-to-FCF is 15.51 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Iterum Therapeutics's current EV-to-FCF is -1.24. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Iterum Therapeutics stock overvalued right now?
Iterum Therapeutics (ITRMF) has a current EV-to-FCF of -1.24. The current EV-to-FCF is -1.24. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-FCF calculated?
EV-to-FCF is calculated from a company's financial statements. For Iterum Therapeutics (ITRMF), the current EV-to-FCF is -1.24 as of Jul. 17, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Iterum Therapeutics PLC is a pharmaceutical company dedicated to maximizing the commercial potential of Orlynvah, an oral-branded penem available in the United States and potentially the first and only oral and intravenous (IV) branded penem available globally. Its product Orlynvah has the potential to be a treatment for complicated urinary tract infections caused by the designated microorganisms, without the presence of known toxicities of some other antibiotics. The company operates in a single business segment, which is the development and commercialization of treatments for drug-resistant bacterial infections.
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