OptiBiotix Health (LSE:OPTI) Piotroski F-Score: 5 (As of Jun. 29, 2026) — 25% Above Median


What is OptiBiotix Health Piotroski F-Score?

OptiBiotix Health LSE:OPTI Piotroski F-Score is 5 as of Jun. 29, 2026, which is 25% above its 10-year median of 4.00. The stock has 4 warning signs investors should review. Among 1,339 Biotechnology companies, OptiBiotix Health ranks better than 85.06% on this metric.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

OptiBiotix Health has an F-score of 5 indicating the company's financial situation is typical for a stable company.

The historical rank and industry rank for OptiBiotix Health's Piotroski F-Score or its related term are showing as below:

LSE:OPTI' s Piotroski F-Score Range Over the Past 10 Years
Min: 3   Med: 4   Max: 5
Current: 5

During the past 13 years, the highest Piotroski F-Score of OptiBiotix Health was 5. The lowest was 3. And the median was 4.

OptiBiotix Health  (LSE:OPTI) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


OptiBiotix Health Piotroski F-Score Related Terms


OptiBiotix Health Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for OptiBiotix Health's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OptiBiotix Health Piotroski F-Score Chart

OptiBiotix Health Annual Data
Trend Nov15 Nov16 Nov17 Nov18 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
Get a 7-Day Free Trial Premium Member Only Premium Member Only 4.00 5.00 5.00 3.00 5.00

OptiBiotix Health Semi-Annual Data
Nov15 May16 Nov16 May17 Nov17 May18 Nov18 May19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Piotroski F-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 5.00 0.00 3.00 0.00 5.00

LSE:OPTI vs VRTX, REGN, ALNY: Piotroski F-Score Comparison

For the Biotechnology subindustry, OptiBiotix Health's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OptiBiotix Health Piotroski F-Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, OptiBiotix Health's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where OptiBiotix Health's Piotroski F-Score falls into.


How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Dec25) TTM:Last Year (Dec24) TTM:
Net Income was £-3.89 Mil.
Cash Flow from Operations was £-1.77 Mil.
Revenue was £1.17 Mil.
Gross Profit was £0.61 Mil.
Average Total Assets from the begining of this year (Dec24)
to the end of this year (Dec25) was (9.045 + 6.892) / 2 = £7.9685 Mil.
Total Assets at the begining of this year (Dec24) was £9.05 Mil.
Long-Term Debt & Capital Lease Obligation was £0.00 Mil.
Total Current Assets was £1.64 Mil.
Total Current Liabilities was £0.38 Mil.
Net Income was £-1.81 Mil.

Revenue was £0.87 Mil.
Gross Profit was £0.33 Mil.
Average Total Assets from the begining of last year (Dec23)
to the end of last year (Dec24) was (9.404 + 9.045) / 2 = £9.2245 Mil.
Total Assets at the begining of last year (Dec23) was £9.40 Mil.
Long-Term Debt & Capital Lease Obligation was £0.00 Mil.
Total Current Assets was £1.42 Mil.
Total Current Liabilities was £0.37 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

OptiBiotix Health's current Net Income (TTM) was -3.89. ==> Negative ==> Score 0.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

OptiBiotix Health's current Cash Flow from Operations (TTM) was -1.77. ==> Negative ==> Score 0.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Dec24)
=-3.89/9.045
=-0.43007186

ROA (Last Year)=Net Income/Total Assets (Dec23)
=-1.805/9.404
=-0.1919396

OptiBiotix Health's return on assets of this year was -0.43007186. OptiBiotix Health's return on assets of last year was -0.1919396. ==> Last year is higher ==> Score 0.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

OptiBiotix Health's current Net Income (TTM) was -3.89. OptiBiotix Health's current Cash Flow from Operations (TTM) was -1.77. ==> -1.77 > -3.89 ==> CFROA > ROA ==> Score 1.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Dec25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec24 to Dec25
=0/7.9685
=0

Gearing (Last Year: Dec24)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec23 to Dec24
=0/9.2245
=0

OptiBiotix Health's gearing of this year was 0. OptiBiotix Health's gearing of last year was 0. ==> This year is lower or equal to last year. ==> Score 1.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Dec25)=Total Current Assets/Total Current Liabilities
=1.641/0.384
=4.2734375

Current Ratio (Last Year: Dec24)=Total Current Assets/Total Current Liabilities
=1.423/0.368
=3.86684783

OptiBiotix Health's current ratio of this year was 4.2734375. OptiBiotix Health's current ratio of last year was 3.86684783. ==> This year's current ratio is higher. ==> Score 1.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

OptiBiotix Health's number of shares in issue this year was 101.201. OptiBiotix Health's number of shares in issue last year was 97.902. ==> There is larger number of shares in issue this year. ==> Score 0.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=0.614/1.166
=0.52658662

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=0.331/0.87
=0.38045977

OptiBiotix Health's gross margin of this year was 0.52658662. OptiBiotix Health's gross margin of last year was 0.38045977. ==> This year's gross margin is higher. ==> Score 1.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Dec24)
=1.166/9.045
=0.128911

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Dec23)
=0.87/9.404
=0.09251382

OptiBiotix Health's asset turnover of this year was 0.128911. OptiBiotix Health's asset turnover of last year was 0.09251382. ==> This year's asset turnover is higher. ==> Score 1.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=0+0+0+1+1+1+0+1+1
=5

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

OptiBiotix Health has an F-score of 5 indicating the company's financial situation is typical for a stable company.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 5 mean?
OptiBiotix Health (LSE:OPTI) has a Piotroski F-Score of 5 as of Jun. 29, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on OptiBiotix Health and its competitors. This is 25% above median its historical median of 4.00. Over the past decade, OptiBiotix Health's Piotroski F-Score has ranged from 3.00 to 5.00. According to the industry distribution chart, OptiBiotix Health ranks #200 out of 1339 companies in the Biotechnology industry, placing it in the top 14.9%.
Is OptiBiotix Health's Piotroski F-Score too high?
OptiBiotix Health's current Piotroski F-Score of 5 is 25% above median its 10-year median of 4.00. Over the past 10 years, this metric has ranged from a low of 3.00 to a high of 5.00. The Biotechnology industry median Piotroski F-Score is 3.00. OptiBiotix Health's value of 5 is 66.7% above this industry median. Based on the distribution chart, OptiBiotix Health ranks #200 out of 1339 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers.
How does OptiBiotix Health's Piotroski F-Score compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, OptiBiotix Health ranks #200 out of 1339 companies for Piotroski F-Score. This places OptiBiotix Health in the top 15% of its industry — outperforming the majority of peers. The industry median Piotroski F-Score is 3.00. OptiBiotix Health's value of 5 is 66.7% above this benchmark. Historically, OptiBiotix Health's own Piotroski F-Score has ranged from 3.00 to 5.00 over the past decade. While the company's 10-year median is 4.00 vs. the industry median of 3.00, OptiBiotix Health has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Biotechnology company?
The median Piotroski F-Score among Biotechnology companies is 3.00, based on 1,339 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. OptiBiotix Health's current Piotroski F-Score of 5 is 66.7% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on OptiBiotix Health and its competitors. For the Biotechnology industry, the median Piotroski F-Score is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. OptiBiotix Health's current Piotroski F-Score is 5, which is 25% above median its own 10-year median of 4.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OptiBiotix Health stock overvalued right now?
Based on GuruFocus' analysis, OptiBiotix Health (LSE:OPTI) is currently considered Possible Value Trap. The stock's GF Value™ is £0.30, compared to a current price of £0.06 — trading 78.8% below its estimated fair value. The current Piotroski F-Score is 5, which is 25% above median its 10-year median of 4.00 and 66.7% above the Biotechnology industry median of 3.00. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For OptiBiotix Health (LSE:OPTI), the current Piotroski F-Score is 5 as of Jun. 29, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

OptiBiotix Health Business Description

Address Innovation Centre, Innovation Way, Heslington, York, GBR, YO10 5DG
OptiBiotix Health PLC principal activity is that of identifying and developing microbial strains, compounds, and formulations for use in food ingredients, supplements and active compounds that can impact on human physiology, deriving potential health benefits. It is a life sciences business focused on the development of products which reduce hunger and food cravings, enhance the gut microbiome, and provide a healthy substitute for sugar. Its product portfolio includes First-generation products- SlimBiome, WellBiome; and Second-generation solutions- SweetBiotix, Microbiome Modulators. The group has one class of business. It has presence in United Kingdom, United States, India China, and Rest of world. The company generates majority of revenue from United States.