OptiBiotix Health (LSE:OPTI) ROA %: -67.64% (As of Dec. 2025)


What is OptiBiotix Health ROA %?

OptiBiotix Health LSE:OPTI ROA % is -67.64% as of Dec. 2025. The stock has 4 warning signs investors should review. Among 1,419 Biotechnology companies, OptiBiotix Health ranks worse than 61.66% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. OptiBiotix Health's annualized Net Income for the quarter that ended in Dec. 2025 was £-5.43 Mil. OptiBiotix Health's average Total Assets over the quarter that ended in Dec. 2025 was £8.02 Mil. Therefore, OptiBiotix Health's annualized ROA % for the quarter that ended in Dec. 2025 was -67.64%.

The historical rank and industry rank for OptiBiotix Health's ROA % or its related term are showing as below:

LSE:OPTI' s ROA % Range Over the Past 10 Years
Min: -48.82   Med: -19.52   Max: 53.39
Current: -46.51

During the past 13 years, OptiBiotix Health's highest ROA % was 53.39%. The lowest was -48.82%. And the median was -19.52%.

LSE:OPTI's ROA % is ranked worse than
61.66% of 1419 companies
in the Biotechnology industry
Industry Median: -32.84 vs LSE:OPTI: -46.51

OptiBiotix Health  (LSE:OPTI) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Dec. 2025 )
=Net Income/Total Assets
=-5.426/8.022
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-5.426 / 1.218)*(1.218 / 8.022)
=Net Margin %*Asset Turnover
=-445.48 %*0.1518
=-67.64 %

Note: The Net Income data used here is two times the semi-annual (Dec. 2025) net income data. The Revenue data used here is two times the semi-annual (Dec. 2025) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


OptiBiotix Health ROA % Related Terms


OptiBiotix Health ROA % Historical Data

* Premium members only.

The historical data trend for OptiBiotix Health's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OptiBiotix Health ROA % Chart

OptiBiotix Health Annual Data
Trend Nov15 Nov16 Nov17 Nov18 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 36.99 16.33 -19.46 -19.57 -48.82

OptiBiotix Health Semi-Annual Data
Nov15 May16 Nov16 May17 Nov17 May18 Nov18 May19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -3.99 -64.04 23.10 -25.87 -67.64

LSE:OPTI vs VRTX, REGN, ALNY: ROA % Comparison

For the Biotechnology subindustry, OptiBiotix Health's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OptiBiotix Health ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, OptiBiotix Health's ROA % distribution charts can be found below:

* The bar in red indicates where OptiBiotix Health's ROA % falls into.



OptiBiotix Health ROA % Calculation

OptiBiotix Health's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-3.89/( (9.045+6.892)/ 2 )
=-3.89/7.9685
=-48.82 %

OptiBiotix Health's annualized ROA % for the quarter that ended in Dec. 2025 is calculated as:

ROA %=Net Income (Q: Dec. 2025 )/( (Total Assets (Q: Jun. 2025 )+Total Assets (Q: Dec. 2025 ))/ count )
=-5.426/( (9.152+6.892)/ 2 )
=-5.426/8.022
=-67.64 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is two times the semi-annual (Dec. 2025) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -67.64% mean?
OptiBiotix Health (LSE:OPTI) has a ROA % of -67.64% as of Dec. 2025. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on OptiBiotix Health and its competitors. According to the industry distribution chart, OptiBiotix Health ranks #875 out of 1419 companies in the Biotechnology industry, placing it in the top 61.7%.
Is OptiBiotix Health's ROA % too high?
OptiBiotix Health's current ROA % is -67.64%. Based on the distribution chart, OptiBiotix Health ranks #875 out of 1419 companies in the Biotechnology industry, which is below the industry midpoint.
How does OptiBiotix Health's ROA % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, OptiBiotix Health ranks #875 out of 1419 companies for ROA %. This places OptiBiotix Health in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on OptiBiotix Health and its competitors. OptiBiotix Health's current ROA % is -67.64%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OptiBiotix Health stock overvalued right now?
Based on GuruFocus' analysis, OptiBiotix Health (LSE:OPTI) is currently considered Possible Value Trap. The stock's GF Value™ is £0.30, compared to a current price of £0.06 — trading 78.8% below its estimated fair value. The current ROA % is -67.64%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For OptiBiotix Health (LSE:OPTI), the current ROA % is -67.64% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

OptiBiotix Health Business Description

Address Innovation Centre, Innovation Way, Heslington, York, GBR, YO10 5DG
OptiBiotix Health PLC principal activity is that of identifying and developing microbial strains, compounds, and formulations for use in food ingredients, supplements and active compounds that can impact on human physiology, deriving potential health benefits. It is a life sciences business focused on the development of products which reduce hunger and food cravings, enhance the gut microbiome, and provide a healthy substitute for sugar. Its product portfolio includes First-generation products- SlimBiome, WellBiome; and Second-generation solutions- SweetBiotix, Microbiome Modulators. The group has one class of business. It has presence in United Kingdom, United States, India China, and Rest of world. The company generates majority of revenue from United States.