OptiBiotix Health (LSE:OPTI) Net Margin %: -445.48% (As of Dec. 2025)


What is OptiBiotix Health Net Margin %?

OptiBiotix Health LSE:OPTI Net Margin % is -445.48% as of Dec. 2025. The stock has 4 warning signs investors should review. Among 946 Biotechnology companies, OptiBiotix Health ranks worse than 66.28% on this metric.

Net margin is calculated as Net Income divided by its Revenue. OptiBiotix Health's Net Income for the six months ended in Dec. 2025 was £-2.71 Mil. OptiBiotix Health's Revenue for the six months ended in Dec. 2025 was £0.61 Mil. Therefore, OptiBiotix Health's net margin for the quarter that ended in Dec. 2025 was -445.48%.

The historical rank and industry rank for OptiBiotix Health's Net Margin % or its related term are showing as below:

LSE:OPTI' s Net Margin % Range Over the Past 10 Years
Min: -4575   Med: -262.04   Max: 998.43
Current: -333.62

LSE:OPTI's Net Margin % is ranked worse than
66.28% of 946 companies
in the Biotechnology industry
Industry Median: -88.815 vs LSE:OPTI: -333.62

OptiBiotix Health  (LSE:OPTI) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.

OptiBiotix Health Net Margin % Related Terms

OptiBiotix Health Net Margin % Historical Data

* Premium members only.

The historical data trend for OptiBiotix Health's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OptiBiotix Health Net Margin % Chart

OptiBiotix Health Annual Data
Trend Nov15 Nov16 Nov17 Nov18 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 282.92 566.08 -316.61 -207.47 -333.62

OptiBiotix Health Semi-Annual Data
Nov15 May16 Nov16 May17 Nov17 May18 Nov18 May19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -65.87 -1,011.23 165.99 -211.31 -445.48

LSE:OPTI vs VRTX, REGN, ALNY: Net Margin % Comparison

For the Biotechnology subindustry, OptiBiotix Health's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

OptiBiotix Health Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, OptiBiotix Health's Net Margin % distribution charts can be found below:

* The bar in red indicates where OptiBiotix Health's Net Margin % falls into.


OptiBiotix Health Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

OptiBiotix Health's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-3.89/1.166
=-333.62 %

OptiBiotix Health's Net Margin for the quarter that ended in Dec. 2025 is calculated as

Net Margin=Net Income (Q: Dec. 2025 )/Revenue (Q: Dec. 2025 )
=-2.713/0.609
=-445.48 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -445.48% mean?
OptiBiotix Health (LSE:OPTI) has a Net Margin % of -445.48% as of Dec. 2025. Net margin is the ratio of total net income to net sales. View historical data on OptiBiotix Health and its competitors. According to the industry distribution chart, OptiBiotix Health ranks #627 out of 946 companies in the Biotechnology industry, placing it in the top 66.3%.
Is OptiBiotix Health's Net Margin % too high?
OptiBiotix Health's current Net Margin % is -445.48%. Based on the distribution chart, OptiBiotix Health ranks #627 out of 946 companies in the Biotechnology industry, which is below the industry midpoint.
How does OptiBiotix Health's Net Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, OptiBiotix Health ranks #627 out of 946 companies for Net Margin %. This places OptiBiotix Health in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on OptiBiotix Health and its competitors. OptiBiotix Health's current Net Margin % is -445.48%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OptiBiotix Health stock overvalued right now?
Based on GuruFocus' analysis, OptiBiotix Health (LSE:OPTI) is currently considered Possible Value Trap. The stock's GF Value™ is £0.30, compared to a current price of £0.06 — trading 78.8% below its estimated fair value. The current Net Margin % is -445.48%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For OptiBiotix Health (LSE:OPTI), the current Net Margin % is -445.48% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

OptiBiotix Health Business Description

Address Innovation Centre, Innovation Way, Heslington, York, GBR, YO10 5DG
OptiBiotix Health PLC principal activity is that of identifying and developing microbial strains, compounds, and formulations for use in food ingredients, supplements and active compounds that can impact on human physiology, deriving potential health benefits. It is a life sciences business focused on the development of products which reduce hunger and food cravings, enhance the gut microbiome, and provide a healthy substitute for sugar. Its product portfolio includes First-generation products- SlimBiome, WellBiome; and Second-generation solutions- SweetBiotix, Microbiome Modulators. The group has one class of business. It has presence in United Kingdom, United States, India China, and Rest of world. The company generates majority of revenue from United States.