PRAX (Praxis Precision Medicines) Net Margin %: 0.00% (As of Mar. 2026)


PRAX Praxis Precision Medicines Inc PRAX
38 GF Score
Price $322.67
GF Value $30.36
Valuation Significantly Overvalued
! 1 Warning Sign
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What is Praxis Precision Medicines Net Margin %?

Praxis Precision Medicines PRAX +4.44% 38 Net Margin % is 0.00% as of Mar. 2026. GuruFocus rates PRAX with a GF Score™ of 38/100 and a GF Value™ of $30.36 (Significantly Overvalued). The stock has 1 warning sign investors should review. Among 947 Biotechnology companies, Praxis Precision Medicines ranks worse than 105596.52% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Praxis Precision Medicines's Net Income for the three months ended in Mar. 2026 was $-92.56 Mil. Praxis Precision Medicines's Revenue for the three months ended in Mar. 2026 was $0.00 Mil. Therefore, Praxis Precision Medicines's net margin for the quarter that ended in Mar. 2026 was 0.00%.

The historical rank and industry rank for Praxis Precision Medicines's Net Margin % or its related term are showing as below:


PRAX's Net Margin % is not ranked *
in the Biotechnology industry.
Industry Median: -89.33
* Ranked among companies with meaningful Net Margin % only.

Praxis Precision Medicines  (NAS:PRAX) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.


Praxis Precision Medicines Net Margin % Related Terms


Praxis Precision Medicines Net Margin % Historical Data

* Premium members only.

The historical data trend for Praxis Precision Medicines's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Praxis Precision Medicines Net Margin % Chart

Praxis Precision Medicines Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
Get a 7-Day Free Trial 0.00 0.00 -5,037.88 -2,137.48 0.00

Praxis Precision Medicines Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

PRAX vs KRYS, CYTK, NUVL: Net Margin % Comparison

For the Biotechnology subindustry, Praxis Precision Medicines's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Praxis Precision Medicines Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Praxis Precision Medicines's Net Margin % distribution charts can be found below:

* The bar in red indicates where Praxis Precision Medicines's Net Margin % falls into.


PRAX
38GF Score
Praxis Precision Medicines Inc PRAX
Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Praxis Precision Medicines Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Praxis Precision Medicines's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-303.268/0
= %

Praxis Precision Medicines's Net Margin for the quarter that ended in Mar. 2026 is calculated as

Net Margin=Net Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-92.561/0
= %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of 0.00% mean?
Praxis Precision Medicines (PRAX) has a Net Margin % of 0.00% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Praxis Precision Medicines and its competitors. According to the industry distribution chart, Praxis Precision Medicines ranks #999999 out of 947 companies in the Biotechnology industry.
Is Praxis Precision Medicines' Net Margin % too high?
Praxis Precision Medicines' current Net Margin % is 0.00%. Based on the distribution chart, Praxis Precision Medicines ranks #999999 out of 947 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Praxis Precision Medicines has a GF Score™ of 38/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Praxis Precision Medicines' Net Margin % compare to KRYS and CYTK?
According to the Biotechnology industry distribution chart, Praxis Precision Medicines ranks #999999 out of 947 companies for Net Margin %. This places Praxis Precision Medicines in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Praxis Precision Medicines and its competitors. Praxis Precision Medicines's current Net Margin % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Praxis Precision Medicines stock overvalued right now?
Based on GuruFocus' analysis, Praxis Precision Medicines (PRAX) is currently considered Significantly Overvalued. The stock's GF Value™ is $30.36, compared to a current price of $322.67 — trading 962.8% above its estimated fair value. The current Net Margin % is 0.00%. Praxis Precision Medicines' overall GF Score™ is 38/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Praxis Precision Medicines (PRAX), the current Net Margin % is 0.00% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Praxis Precision Medicines (PRAX) Overvalued in 2026?

Based on GuruFocus' analysis, Praxis Precision Medicines stock appears to be overvalued. The current stock price of $322.67 is trading 962.8% above its estimated GF Value™ of $30.36. GuruFocus considers Praxis Precision Medicines to be Significantly Overvalued.

Key valuation signals for PRAX:

  • Net Margin %: 0.00%
  • GF Value™: $30.36 vs. price of $322.67 (962.8% above fair value)
  • GF Score™: 38/100 with 1 warning sign

No single metric tells the full story. See the PRAX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Praxis Precision Medicines Business Description

Address 99 High Street, 30th Floor, Boston, MA, USA, 02110
Praxis Precision Medicines Inc is a clinical-stage biopharmaceutical company. It is engaged in translating genetic insights into the development of therapies for patients affected by central nervous system disorders characterized by a neuronal excitation-inhibition imbalance. The company applies genetic insights to the discovery and development of therapies for neurological disorders through two proprietary platforms: Cerebrum and Solidus. It has established a diversified, multimodal CNS portfolio with four clinical-stage product candidates across movement disorders and epilepsy, which include Ulixacaltamide, Relutrigine, Vormatrigine, and Elsunersen. The firm operates in only one segment and is focused on discovering and developing therapies for CNS disorders.
38GF Score

Get the complete analysis for PRAX

Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$322.67
Price
$30.36
GF Value