XERS (Xeris Biopharma Holdings) Net Margin %: 2.69% (As of Mar. 2026)


XERS Xeris Biopharma Holdings Inc XERS
71 GF Score
Price $8.35
GF Value $5.19
Valuation Significantly Overvalued
! 6 Warning Signs
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What is Xeris Biopharma Holdings Net Margin %?

Xeris Biopharma Holdings XERS -3.30% 71 Net Margin % is 2.69% as of Mar. 2026. GuruFocus rates XERS with a GF Score™ of 71/100 and a GF Value™ of $5.19 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 962 Drug Manufacturers companies, Xeris Biopharma Holdings ranks worse than 55.3% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Xeris Biopharma Holdings's Net Income for the three months ended in Mar. 2026 was $2.2 Mil. Xeris Biopharma Holdings's Revenue for the three months ended in Mar. 2026 was $83.1 Mil. Therefore, Xeris Biopharma Holdings's net margin for the quarter that ended in Mar. 2026 was 2.69%.

The historical rank and industry rank for Xeris Biopharma Holdings's Net Margin % or its related term are showing as below:

XERS' s Net Margin % Range Over the Past 10 Years
Min: -4613.52   Med: -346.74   Max: 3.81
Current: 3.81


XERS's Net Margin % is ranked worse than
55.3% of 962 companies
in the Drug Manufacturers industry
Industry Median: 5.56 vs XERS: 3.81

Xeris Biopharma Holdings  (NAS:XERS) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.


Xeris Biopharma Holdings Net Margin % Related Terms


Xeris Biopharma Holdings Net Margin % Historical Data

* Premium members only.

The historical data trend for Xeris Biopharma Holdings's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Xeris Biopharma Holdings Net Margin % Chart

Xeris Biopharma Holdings Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -247.48 -85.86 -37.98 -27.00 0.19

Xeris Biopharma Holdings Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -15.34 -2.70 0.83 12.91 2.69

XERS vs PAHC, PRGO, ALVO: Net Margin % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Xeris Biopharma Holdings's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Xeris Biopharma Holdings Net Margin % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Xeris Biopharma Holdings's Net Margin % distribution charts can be found below:

* The bar in red indicates where Xeris Biopharma Holdings's Net Margin % falls into.


XERS
71GF Score
Xeris Biopharma Holdings Inc XERS
Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Xeris Biopharma Holdings Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Xeris Biopharma Holdings's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=0.554/291.845
=0.19 %

Xeris Biopharma Holdings's Net Margin for the quarter that ended in Mar. 2026 is calculated as

Net Margin=Net Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=2.234/83.127
=2.69 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of 2.69% mean?
Xeris Biopharma Holdings (XERS) has a Net Margin % of 2.69% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Xeris Biopharma Holdings and its competitors. According to the industry distribution chart, Xeris Biopharma Holdings ranks #532 out of 962 companies in the Drug Manufacturers industry, placing it in the top 55.3%.
Is Xeris Biopharma Holdings' Net Margin % too high?
Xeris Biopharma Holdings' current Net Margin % is 2.69%. The Drug Manufacturers industry median Net Margin % is 5.56. Xeris Biopharma Holdings' value of 2.69% is 51.6% below this industry median. Based on the distribution chart, Xeris Biopharma Holdings ranks #532 out of 962 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, Xeris Biopharma Holdings has a GF Score™ of 71/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Xeris Biopharma Holdings' Net Margin % compare to PAHC and PRGO?
According to the Drug Manufacturers industry distribution chart, Xeris Biopharma Holdings ranks #532 out of 962 companies for Net Margin %. This places Xeris Biopharma Holdings in the lower half of its industry. The industry median Net Margin % is 5.56. Xeris Biopharma Holdings' value of 2.69% is 51.6% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Drug Manufacturers company?
The median Net Margin % among Drug Manufacturers companies is 5.56, based on 962 companies in the industry. Companies in the top quartile (top 25%) have a Net Margin % significantly above this median, while those in the bottom quartile fall well below. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Xeris Biopharma Holdings's current Net Margin % of 2.69% is 51.6% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Xeris Biopharma Holdings and its competitors. For the Drug Manufacturers industry, the median Net Margin % is 5.56 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Xeris Biopharma Holdings's current Net Margin % is 2.69%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Xeris Biopharma Holdings stock overvalued right now?
Based on GuruFocus' analysis, Xeris Biopharma Holdings (XERS) is currently considered Significantly Overvalued. The stock's GF Value™ is $5.19, compared to a current price of $8.35 — trading 60.9% above its estimated fair value. The current Net Margin % is 2.69% and 51.6% below the Drug Manufacturers industry median of 5.56. Xeris Biopharma Holdings' overall GF Score™ is 71/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Xeris Biopharma Holdings (XERS), the current Net Margin % is 2.69% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Xeris Biopharma Holdings (XERS) Overvalued in 2026?

Based on GuruFocus' analysis, Xeris Biopharma Holdings stock appears to be overvalued. The current stock price of $8.35 is trading 60.9% above its estimated GF Value™ of $5.19. GuruFocus considers Xeris Biopharma Holdings to be Significantly Overvalued.

Key valuation signals for XERS:

  • Net Margin %: 2.69%
  • GF Value™: $5.19 vs. price of $8.35 (60.9% above fair value)
  • GF Score™: 71/100 with 6 warning signs
  • Industry Position: 51.6% below the Drug Manufacturers median (#532 of 962)

No single metric tells the full story. See the XERS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Xeris Biopharma Holdings Business Description

Other Exchanges 0A8E:UK2B30:Germany
Address 1375 West Fulton Street, Suite 1300, Chicago, IL, USA, 60607
Xeris Biopharma Holdings Inc is a commercial-stage biopharmaceutical company focused on developing and commercializing therapies for people with chronic endocrine and neurological diseases in the United States. It offers Recorlev for the treatment of endogenous hypercortisolemia in patients with Cushing's syndrome; Gvoke for the treatment of severe hypoglycemia; and Keveyis for the treatment of Primary Periodic Paralysis (PPP). Additionally, the company is advancing its Phase 3-ready pipeline product, XP-8121, a once-weekly subcutaneous injection of levothyroxine, which leverages its proprietary technology, XeriSol.
71GF Score

Get the complete analysis for XERS

Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$8.35
Price
$5.19
GF Value