XERS (Xeris Biopharma Holdings) ROA %: 2.30% (As of Mar. 2026)


XERS Xeris Biopharma Holdings Inc XERS
71 GF Score
Price $8.35
GF Value $5.19
Valuation Significantly Overvalued
! 6 Warning Signs
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What is Xeris Biopharma Holdings ROA %?

Xeris Biopharma Holdings XERS -3.30% 71 ROA % is 2.30% as of Mar. 2026. GuruFocus rates XERS with a GF Score™ of 71/100 and a GF Value™ of $5.19 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 1,009 Drug Manufacturers companies, Xeris Biopharma Holdings ranks better than 53.32% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Xeris Biopharma Holdings's annualized Net Income for the quarter that ended in Mar. 2026 was $8.9 Mil. Xeris Biopharma Holdings's average Total Assets over the quarter that ended in Mar. 2026 was $387.8 Mil. Therefore, Xeris Biopharma Holdings's annualized ROA % for the quarter that ended in Mar. 2026 was 2.30%.

The historical rank and industry rank for Xeris Biopharma Holdings's ROA % or its related term are showing as below:

XERS' s ROA % Range Over the Past 10 Years
Min: -109.67   Med: -46.17   Max: 3.34
Current: 3.34

During the past 10 years, Xeris Biopharma Holdings's highest ROA % was 3.34%. The lowest was -109.67%. And the median was -46.17%.

XERS's ROA % is ranked better than
53.32% of 1009 companies
in the Drug Manufacturers industry
Industry Median: 2.74 vs XERS: 3.34

Xeris Biopharma Holdings  (NAS:XERS) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=8.936/387.77
=(Net Income / Revenue)*(Revenue / Total Assets)
=(8.936 / 332.508)*(332.508 / 387.77)
=Net Margin %*Asset Turnover
=2.69 %*0.8575
=2.30 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Xeris Biopharma Holdings ROA % Related Terms


Xeris Biopharma Holdings ROA % Historical Data

* Premium members only.

The historical data trend for Xeris Biopharma Holdings's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Xeris Biopharma Holdings ROA % Chart

Xeris Biopharma Holdings Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -52.95 -29.18 -18.66 -16.99 0.16

Xeris Biopharma Holdings Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -11.55 -2.37 0.70 11.76 2.30

XERS vs PAHC, PRGO, ALVO: ROA % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Xeris Biopharma Holdings's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Xeris Biopharma Holdings ROA % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Xeris Biopharma Holdings's ROA % distribution charts can be found below:

* The bar in red indicates where Xeris Biopharma Holdings's ROA % falls into.


XERS
71GF Score
Xeris Biopharma Holdings Inc XERS
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
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Xeris Biopharma Holdings ROA % Calculation

Xeris Biopharma Holdings's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=0.554/( (323.06+383.527)/ 2 )
=0.554/353.2935
=0.16 %

Xeris Biopharma Holdings's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=8.936/( (383.527+392.013)/ 2 )
=8.936/387.77
=2.30 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of 2.30% mean?
Xeris Biopharma Holdings (XERS) has a ROA % of 2.30% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Xeris Biopharma Holdings and its competitors. According to the industry distribution chart, Xeris Biopharma Holdings ranks #471 out of 1009 companies in the Drug Manufacturers industry, placing it in the top 46.7%.
Is Xeris Biopharma Holdings' ROA % too high?
Xeris Biopharma Holdings' current ROA % is 2.30%. The Drug Manufacturers industry median ROA % is 2.74. Xeris Biopharma Holdings' value of 2.30% is 16.1% below this industry median. Based on the distribution chart, Xeris Biopharma Holdings ranks #471 out of 1009 companies in the Drug Manufacturers industry, which is above the industry midpoint. Overall, Xeris Biopharma Holdings has a GF Score™ of 71/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Xeris Biopharma Holdings' ROA % compare to PAHC and PRGO?
According to the Drug Manufacturers industry distribution chart, Xeris Biopharma Holdings ranks #471 out of 1009 companies for ROA %. This puts Xeris Biopharma Holdings in the upper half of its industry. The industry median ROA % is 2.74. Xeris Biopharma Holdings' value of 2.30% is 16.1% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Drug Manufacturers company?
The median ROA % among Drug Manufacturers companies is 2.74, based on 1,009 companies in the industry. Companies in the top quartile (top 25%) have a ROA % significantly above this median, while those in the bottom quartile fall well below. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Xeris Biopharma Holdings's current ROA % of 2.30% is 16.1% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Xeris Biopharma Holdings and its competitors. For the Drug Manufacturers industry, the median ROA % is 2.74 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Xeris Biopharma Holdings's current ROA % is 2.30%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Xeris Biopharma Holdings stock overvalued right now?
Based on GuruFocus' analysis, Xeris Biopharma Holdings (XERS) is currently considered Significantly Overvalued. The stock's GF Value™ is $5.19, compared to a current price of $8.35 — trading 60.9% above its estimated fair value. The current ROA % is 2.30% and 16.1% below the Drug Manufacturers industry median of 2.74. Xeris Biopharma Holdings' overall GF Score™ is 71/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Xeris Biopharma Holdings (XERS), the current ROA % is 2.30% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Xeris Biopharma Holdings (XERS) Overvalued in 2026?

Based on GuruFocus' analysis, Xeris Biopharma Holdings stock appears to be overvalued. The current stock price of $8.35 is trading 60.9% above its estimated GF Value™ of $5.19. GuruFocus considers Xeris Biopharma Holdings to be Significantly Overvalued.

Key valuation signals for XERS:

  • ROA %: 2.30%
  • GF Value™: $5.19 vs. price of $8.35 (60.9% above fair value)
  • GF Score™: 71/100 with 6 warning signs
  • Industry Position: 16.1% below the Drug Manufacturers median (#471 of 1009)

No single metric tells the full story. See the XERS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Xeris Biopharma Holdings Business Description

Other Exchanges 0A8E:UK2B30:Germany
Address 1375 West Fulton Street, Suite 1300, Chicago, IL, USA, 60607
Xeris Biopharma Holdings Inc is a commercial-stage biopharmaceutical company focused on developing and commercializing therapies for people with chronic endocrine and neurological diseases in the United States. It offers Recorlev for the treatment of endogenous hypercortisolemia in patients with Cushing's syndrome; Gvoke for the treatment of severe hypoglycemia; and Keveyis for the treatment of Primary Periodic Paralysis (PPP). Additionally, the company is advancing its Phase 3-ready pipeline product, XP-8121, a once-weekly subcutaneous injection of levothyroxine, which leverages its proprietary technology, XeriSol.
71GF Score

Get the complete analysis for XERS

ROA % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$8.35
Price
$5.19
GF Value