APLIF (Appili Therapeutics) OCF Margin %: -244.58% (As of Dec. 2025)


What is Appili Therapeutics OCF Margin %?

Appili Therapeutics APLIF OCF Margin % is -244.58% as of Dec. 2025. The stock has 4 warning signs investors should review. Among 959 Biotechnology companies, Appili Therapeutics ranks better than 65.07% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. Appili Therapeutics's Cash Flow from Operations for the three months ended in Dec. 2025 was $-0.20 Mil. Appili Therapeutics's Revenue for the three months ended in Dec. 2025 was $0.08 Mil. Therefore, Appili Therapeutics's OCF Margin % for the quarter that ended in Dec. 2025 was -244.58%.

As of today, Appili Therapeutics's current OCF Yield % is -2.66%.

The historical rank and industry rank for Appili Therapeutics's OCF Margin % or its related term are showing as below:

APLIF' s OCF Margin % Range Over the Past 10 Years
Min: -3023.35   Med: -1371.75   Max: 869
Current: -24.16

During the past 8 years, the highest OCF Margin % of Appili Therapeutics was 869.00%. The lowest was -3023.35%. And the median was -1371.75%.

APLIF's OCF Margin % is ranked better than
65.07% of 959 companies
in the Biotechnology industry
Industry Median: -66.52 vs APLIF: -24.16

Appili Therapeutics OCF Margin % Related Terms

Appili Therapeutics OCF Margin % Historical Data

* Premium members only.

The historical data trend for Appili Therapeutics's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Appili Therapeutics OCF Margin % Chart

Appili Therapeutics Annual Data
Trend Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25
OCF Margin %
Get a 7-Day Free Trial 0.00 -1,371.43 -3,024.59 -297.87 864.29

Appili Therapeutics Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
OCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -407.89 -8,000.00 0.00 -732.00 -244.58

APLIF vs VRTX, REGN, ALNY: OCF Margin % Comparison

For the Biotechnology subindustry, Appili Therapeutics's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Appili Therapeutics OCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Appili Therapeutics's OCF Margin % distribution charts can be found below:

* The bar in red indicates where Appili Therapeutics's OCF Margin % falls into.


Appili Therapeutics OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

Appili Therapeutics's OCF Margin for the fiscal year that ended in Mar. 2025 is calculated as

OCF Margin=Cash Flow from Operations (A: Mar. 2025 )/Revenue (A: Mar. 2025 )
=0.605/0.07
=864.29 %

Appili Therapeutics's OCF Margin for the quarter that ended in Dec. 2025 is calculated as

OCF Margin=Cash Flow from Operations (Q: Dec. 2025 )/Revenue (Q: Dec. 2025 )
=-0.203/0.083
=-244.58 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Margin % →
What does a OCF Margin % of -244.58% mean?
Appili Therapeutics (APLIF) has a OCF Margin % of -244.58% as of Dec. 2025. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Appili Therapeutics and its competitors. According to the industry distribution chart, Appili Therapeutics ranks #335 out of 959 companies in the Biotechnology industry, placing it in the top 34.9%.
Is Appili Therapeutics' OCF Margin % too high?
Appili Therapeutics' current OCF Margin % is -244.58%. Based on the distribution chart, Appili Therapeutics ranks #335 out of 959 companies in the Biotechnology industry, which is above the industry midpoint.
How does Appili Therapeutics' OCF Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Appili Therapeutics ranks #335 out of 959 companies for OCF Margin %. This puts Appili Therapeutics in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Biotechnology company?
A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Appili Therapeutics and its competitors. Appili Therapeutics's current OCF Margin % is -244.58%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Appili Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Appili Therapeutics (APLIF) is currently considered Modestly Overvalued. The stock's GF Value™ is $0.01, compared to a current price of $0.01 — trading 13% above its estimated fair value. The current OCF Margin % is -244.58%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For Appili Therapeutics (APLIF), the current OCF Margin % is -244.58% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Appili Therapeutics Business Description

Other Exchanges APLI:Canada
Address 1344 Summer Street, Suite 21, Halifax, NS, CAN, B3H 0A8
Appili Therapeutics Inc is a biopharmaceutical company. The company is engaged in novel antibiotic and anti-infective therapies to help patients suffering from serious infections. Its anti-infective portfolio currently includes programs namely ATI-1701, ATI-1801.