4basebio (LSE:4BB) OCF Margin %: -1,430.83% (As of Dec. 2025)


LSE:4BB 4basebio PLC LSE:4BB
61 GF Score
Price £5.25
GF Value £28.18
Valuation Possible Value Trap
! 7 Warning Signs
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What is 4basebio OCF Margin %?

4basebio LSE:4BB 61 OCF Margin % is -1,430.83% as of Dec. 2025. GuruFocus rates LSE:4BB with a GF Score™ of 61/100 and a GF Value™ of £28.18 (Possible Value Trap). The stock has 7 warning signs investors should review. Among 959 Biotechnology companies, 4basebio ranks worse than 79.35% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. 4basebio's Cash Flow from Operations for the six months ended in Dec. 2025 was £-7.43 Mil. 4basebio's Revenue for the six months ended in Dec. 2025 was £0.52 Mil. Therefore, 4basebio's OCF Margin % for the quarter that ended in Dec. 2025 was -1,430.83%.

As of today, 4basebio's current OCF Yield % is -19.17%.

The historical rank and industry rank for 4basebio's OCF Margin % or its related term are showing as below:

LSE:4BB' s OCF Margin % Range Over the Past 10 Years
Min: -1755.22   Med: -920.73   Max: -133.17
Current: -920.73


During the past 7 years, the highest OCF Margin % of 4basebio was -133.17%. The lowest was -1755.22%. And the median was -920.73%.

LSE:4BB's OCF Margin % is ranked worse than
79.35% of 959 companies
in the Biotechnology industry
Industry Median: -66.52 vs LSE:4BB: -920.73


4basebio OCF Margin % Related Terms


4basebio OCF Margin % Historical Data

* Premium members only.

The historical data trend for 4basebio's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

4basebio OCF Margin % Chart

4basebio Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Margin %
Get a 7-Day Free Trial -810.65 -1,755.22 -1,220.95 -1,151.55 -920.73

4basebio Semi-Annual Data
Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
OCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1,190.67 -1,567.38 -926.12 -695.23 -1,430.83

LSE:4BB vs VRTX, REGN, ALNY: OCF Margin % Comparison

For the Biotechnology subindustry, 4basebio's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


4basebio OCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, 4basebio's OCF Margin % distribution charts can be found below:

* The bar in red indicates where 4basebio's OCF Margin % falls into.


LSE:4BB
61GF Score
4basebio PLC LSE:4BB
OCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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4basebio OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

4basebio's OCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

OCF Margin=Cash Flow from Operations (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-15.588/1.693
=-920.73 %

4basebio's OCF Margin for the quarter that ended in Dec. 2025 is calculated as

OCF Margin=Cash Flow from Operations (Q: Dec. 2025 )/Revenue (Q: Dec. 2025 )
=-7.426/0.519
=-1,430.83 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Margin % →
What does a OCF Margin % of -1,430.83% mean?
4basebio (LSE:4BB) has a OCF Margin % of -1,430.83% as of Dec. 2025. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on 4basebio and its competitors. According to the industry distribution chart, 4basebio ranks #761 out of 959 companies in the Biotechnology industry, placing it in the top 79.4%.
Is 4basebio's OCF Margin % too high?
4basebio's current OCF Margin % is -1,430.83%. Based on the distribution chart, 4basebio ranks #761 out of 959 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, 4basebio has a GF Score™ of 61/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does 4basebio's OCF Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, 4basebio ranks #761 out of 959 companies for OCF Margin %. This places 4basebio in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Biotechnology company?
A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on 4basebio and its competitors. 4basebio's current OCF Margin % is -1,430.83%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is 4basebio stock overvalued right now?
Based on GuruFocus' analysis, 4basebio (LSE:4BB) is currently considered Possible Value Trap. The stock's GF Value™ is £28.18, compared to a current price of £5.25 — trading 81.4% below its estimated fair value. The current OCF Margin % is -1,430.83%. 4basebio's overall GF Score™ is 61/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For 4basebio (LSE:4BB), the current OCF Margin % is -1,430.83% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is 4basebio (LSE:4BB) Overvalued in 2026?

Based on GuruFocus' analysis, 4basebio stock appears to be undervalued. The current stock price of £5.25 is trading 81.4% below its estimated GF Value™ of £28.18. GuruFocus considers 4basebio to be Possible Value Trap.

Key valuation signals for LSE:4BB:

  • OCF Margin %: -1,430.83%
  • GF Value™: £28.18 vs. price of £5.25 (81.4% below fair value)
  • GF Score™: 61/100 with 7 warning signs

No single metric tells the full story. See the LSE:4BB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


4basebio Business Description

Other Exchanges 88Q:Germany
Address 25 Norman Way, Over, Cambridge, GBR, CB24 5QE
4basebio PLC is a life sciences group focused on therapeutic DNA for gene therapies and DNA vaccines and providing solutions for effectively and safely delivering these DNA-based products to patients. The company operates across three geographic segments: Europe, the United States, and the Rest of the World, with the majority of its revenue generated from the United States.
61GF Score

Get the complete analysis for LSE:4BB

OCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

£5.25
Price
£28.18
GF Value