4basebio (LSE:4BB) ROC %: -157.19% (As of Dec. 2025)


LSE:4BB 4basebio PLC LSE:4BB
61 GF Score
Price £5.25
GF Value £28.18
Valuation Possible Value Trap
! 7 Warning Signs
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What is 4basebio ROC %?

4basebio LSE:4BB 61 ROC % is -157.19% as of Dec. 2025. GuruFocus rates LSE:4BB with a GF Score™ of 61/100 and a GF Value™ of £28.18 (Possible Value Trap). The stock has 7 warning signs investors should review.

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. 4basebio's annualized return on capital (ROC %) for the quarter that ended in Dec. 2025 was -157.19%.

As of today (2026-06-26), 4basebio's WACC % is 9.52%. 4basebio's ROC % is -160.21% (calculated using TTM income statement data). 4basebio earns returns that do not match up to its cost of capital. It will destroy value as it grows.


4basebio  (LSE:4BB) ROC % Explanation

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, 4basebio's WACC % is 9.52%. 4basebio's ROC % is -160.21% (calculated using TTM income statement data). 4basebio earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Be Aware

Like ROE % and ROA %, ROC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


4basebio ROC % Related Terms


4basebio ROC % Historical Data

* Premium members only.

The historical data trend for 4basebio's ROC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

4basebio ROC % Chart

4basebio Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROC %
Get a 7-Day Free Trial -68.73 -81.54 -97.74 -139.36 -159.20

4basebio Semi-Annual Data
Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -100.99 -128.02 -156.95 -164.27 -157.19
LSE:4BB
61GF Score
4basebio PLC LSE:4BB
ROC % is just one metric. See GF Score™, valuation, warning signs, and more.
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4basebio ROC % Calculation

4basebio's annualized Return on Capital (ROC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=-16.664 * ( 1 - 3.97% )/( (9.41 + 10.694)/ 2 )
=-16.0024392/10.052
=-159.20 %

where

4basebio's annualized Return on Capital (ROC %) for the quarter that ended in Dec. 2025 is calculated as:

ROC % (Q: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Jun. 2025 ) + Invested Capital (Q: Dec. 2025 ))/ count )
=-16.652 * ( 1 - 2.98% )/( (9.862 + 10.694)/ 2 )
=-16.1557704/10.278
=-157.19 %

where

Note: The Operating Income data used here is two times the semi-annual (Dec. 2025) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROC % →
What does a ROC % of -157.19% mean?
4basebio (LSE:4BB) has a ROC % of -157.19% as of Dec. 2025. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on 4basebio and its competitors.
Is 4basebio's ROC % too high?
4basebio's current ROC % is -157.19%. Overall, 4basebio has a GF Score™ of 61/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does 4basebio's ROC % compare to VRTX and REGN?
4basebio's ROC % of -157.19% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROC % for a Biotechnology company?
A good ROC % depends on the Biotechnology industry context. However, ROC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROC % mean?
A high ROC % can signal that a stock is expensive relative to its fundamentals. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on 4basebio and its competitors. 4basebio's current ROC % is -157.19%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is 4basebio stock overvalued right now?
Based on GuruFocus' analysis, 4basebio (LSE:4BB) is currently considered Possible Value Trap. The stock's GF Value™ is £28.18, compared to a current price of £5.25 — trading 81.4% below its estimated fair value. The current ROC % is -157.19%. 4basebio's overall GF Score™ is 61/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROC % calculated?
ROC % is calculated from a company's financial statements. For 4basebio (LSE:4BB), the current ROC % is -157.19% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is 4basebio (LSE:4BB) Overvalued in 2026?

Based on GuruFocus' analysis, 4basebio stock appears to be undervalued. The current stock price of £5.25 is trading 81.4% below its estimated GF Value™ of £28.18. GuruFocus considers 4basebio to be Possible Value Trap.

Key valuation signals for LSE:4BB:

  • ROC %: -157.19%
  • GF Value™: £28.18 vs. price of £5.25 (81.4% below fair value)
  • GF Score™: 61/100 with 7 warning signs

No single metric tells the full story. See the LSE:4BB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


4basebio Business Description

Other Exchanges 88Q:Germany
Address 25 Norman Way, Over, Cambridge, GBR, CB24 5QE
4basebio PLC is a life sciences group focused on therapeutic DNA for gene therapies and DNA vaccines and providing solutions for effectively and safely delivering these DNA-based products to patients. The company operates across three geographic segments: Europe, the United States, and the Rest of the World, with the majority of its revenue generated from the United States.
61GF Score

Get the complete analysis for LSE:4BB

ROC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

£5.25
Price
£28.18
GF Value