4basebio (LSE:4BB) 1-Year Sharpe Ratio: -2.63 (As of Aug. 27, 2026)

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Director of Data and Quant Analytics at GuruFocus
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Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

LSE:4BB 4basebio PLC LSE:4BB
57 GF Score
Price £4.75
GF Value £29.06
Valuation Possible Value Trap
! 7 Warning Signs
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What is 4basebio 1-Year Sharpe Ratio?

4basebio LSE:4BB +1.06% 57 1-Year Sharpe Ratio is -2.63 as of Aug. 27, 2026. GuruFocus rates LSE:4BB with a GF Score™ of 57/100 and a GF Value™ of £29.06 (Possible Value Trap). The stock has 7 warning signs investors should review.

The 1-Year Sharpe Ratio measures the additional return that an investor receives per unit of increase in risk over the past year. As of today (2026-08-27), 4basebio's 1-Year Sharpe Ratio is -2.63.

4basebio  (LSE:4BB) 1-Year Sharpe Ratio Explanation

The 1-Year Sharpe Ratio inidicates the risk-adjusted return of an investment over the past year. It is calculated as the annualized result of the average monthly excess return divided by its standard deviation over the past year. The monthly excess return is the monthly investment return minus the monthly risk-free rate (typically the 10-year Treasury Constant Maturity Rate). If the risk-free rate for a specific region is not available, U.S. data is used by default.

The greater a portfolio's Sharpe Ratio, the better its risk-adjusted performance. A negative Sharpe Ratio means the risk-free rate is greater than the portfolio’s historical or projected return, or else the portfolio's return is expected to be negative.

4basebio 1-Year Sharpe Ratio Related Terms

LSE:4BB vs VRTX, REGN, RVMD: 1-Year Sharpe Ratio Comparison

For the Biotechnology subindustry, 4basebio's 1-Year Sharpe Ratio, along with its competitors' market caps and 1-Year Sharpe Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

4basebio 1-Year Sharpe Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, 4basebio's 1-Year Sharpe Ratio distribution charts can be found below:

* The bar in red indicates where 4basebio's 1-Year Sharpe Ratio falls into.


LSE:4BB
57GF Score
4basebio PLC LSE:4BB
1-Year Sharpe Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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4basebio 1-Year Sharpe Ratio Calculation

The 1-Year Sharpe Ratio measures the performance of an investment such as a stock or portfolio compared to a risk-free asset. A stock / portfolio's 1-Year Sharpe Ratio can be calculated by dividing the difference between the one-year returns of the investment and the risk-free rate, by the standard deviation of the investment returns over one year.

Frequently Asked Questions Learn more about 1-Year Sharpe Ratio →
What does a 1-Year Sharpe Ratio of -2.63 mean?
4basebio (LSE:4BB) has a 1-Year Sharpe Ratio of -2.63 as of Aug. 27, 2026. 1-Year Sharpe Ratio measures the additional return that an investor receives per unit of increase in risk. View historical data for 4basebio and its competitors.
Is 4basebio's 1-Year Sharpe Ratio too high?
4basebio's current 1-Year Sharpe Ratio is -2.63. Overall, 4basebio has a GF Score™ of 57/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does 4basebio's 1-Year Sharpe Ratio compare to VRTX and REGN?
4basebio's 1-Year Sharpe Ratio of -2.63 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 1-Year Sharpe Ratio for a Biotechnology company?
A good 1-Year Sharpe Ratio depends on the Biotechnology industry context. However, 1-Year Sharpe Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 1-Year Sharpe Ratio mean?
A high 1-Year Sharpe Ratio can signal that a stock is expensive relative to its fundamentals. 1-Year Sharpe Ratio measures the additional return that an investor receives per unit of increase in risk. View historical data for 4basebio and its competitors. 4basebio's current 1-Year Sharpe Ratio is -2.63. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is 4basebio stock overvalued right now?
Based on GuruFocus' analysis, 4basebio (LSE:4BB) is currently considered Possible Value Trap. The stock's GF Value™ is £29.06, compared to a current price of £4.75 — trading 83.7% below its estimated fair value. The current 1-Year Sharpe Ratio is -2.63. 4basebio's overall GF Score™ is 57/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 1-Year Sharpe Ratio calculated?
1-Year Sharpe Ratio is calculated from a company's financial statements. For 4basebio (LSE:4BB), the current 1-Year Sharpe Ratio is -2.63 as of Aug. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is 4basebio (LSE:4BB) Overvalued in 2026?

Based on GuruFocus' analysis, 4basebio stock appears to be undervalued. The current stock price of £4.75 is trading 83.7% below its estimated GF Value™ of £29.06. GuruFocus considers 4basebio to be Possible Value Trap.

Key valuation signals for LSE:4BB:

  • 1-Year Sharpe Ratio: -2.63
  • GF Value™: £29.06 vs. price of £4.75 (83.7% below fair value)
  • GF Score™: 57/100 with 7 warning signs

No single metric tells the full story. See the LSE:4BB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

4basebio Business Description

Other Exchanges 88Q:Germany
Address 25 Norman Way, Over, Cambridge, GBR, CB24 5QE
4basebio PLC is a life sciences group focused on therapeutic DNA for gene therapies and DNA vaccines and providing solutions for effectively and safely delivering these DNA-based products to patients. The company operates across three geographic segments: Europe, the United States, and the Rest of the World, with the majority of its revenue generated from the United States.
57GF Score

Get the complete analysis for LSE:4BB

1-Year Sharpe Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

£4.75
Price
£29.06
GF Value