IlluminaMIL:1ILMN 49 OCF Margin % is 26.49% as of Mar. 2026, which is 3% below its 10-year median of 27.25. GuruFocus rates MIL:1ILMN with a GF Score™ of 49/100 and a GF Value™ of €104.58 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 204 Medical Diagnostics & Research companies, Illumina ranks better than 86.27% on this metric.
The historical rank and industry rank for Illumina's OCF Margin % or its related term are showing as below:
MIL:1ILMN'
s OCF Margin % Range Over the Past 10 Years
Min: 8.55 Med: 27.25 Max: 34.26
Current: 25.67
During the past 13 years, the highest OCF Margin % of Illumina was 34.26%. The lowest was 8.55%. And the median was 27.25%.
MIL:1ILMN's OCF Margin % is ranked better than 86.27% of 204
companies
in the Medical Diagnostics & Research industry
Industry Median: 4.755
vs MIL:1ILMN: 25.67
Illumina OCF Margin % Related Terms
Illumina OCF Margin % Historical Data
* Premium members only.
The historical data trend for Illumina's OCF Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
MIL:1ILMN vs MTD, DGX, LH: OCF Margin % Comparison
For the Diagnostics & Research subindustry, Illumina's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Illumina OCF Margin % vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, Illumina's OCF Margin % distribution charts can be found below:
* The bar in red indicates where Illumina's OCF Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Illumina (MIL:1ILMN) has a OCF Margin % of 26.49% as of Mar. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Illumina and its competitors. This is near median its historical median of 27.25. Over the past decade, Illumina's OCF Margin % has ranged from 8.55 to 34.26. According to the industry distribution chart, Illumina ranks #28 out of 204 companies in the Medical Diagnostics & Research industry, placing it in the top 13.7%.
Is Illumina's OCF Margin % too high?
Illumina's current OCF Margin % of 26.49% is near median its 10-year median of 27.25. Over the past 10 years, this metric has ranged from a low of 8.55 to a high of 34.26. The Medical Diagnostics & Research industry median OCF Margin % is 4.76. Illumina's value of 26.49% is 457.1% above this industry median. Based on the distribution chart, Illumina ranks #28 out of 204 companies in the Medical Diagnostics & Research industry, which is in the top quartile — a strong position relative to peers. Overall, Illumina has a GF Score™ of 49/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Illumina's OCF Margin % compare to MTD and DGX?
According to the Medical Diagnostics & Research industry distribution chart, Illumina ranks #28 out of 204 companies for OCF Margin %. This places Illumina in the top 14% of its industry — outperforming the majority of peers. The industry median OCF Margin % is 4.76. Illumina's value of 26.49% is 457.1% above this benchmark. Historically, Illumina's own OCF Margin % has ranged from 8.55 to 34.26 over the past decade. While the company's 10-year median is 27.25 vs. the industry median of 4.76, Illumina has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Medical Diagnostics & Research company?
The median OCF Margin % among Medical Diagnostics & Research companies is 4.76, based on 204 companies in the industry. Companies in the top quartile (top 25%) have a OCF Margin % significantly above this median, while those in the bottom quartile fall well below. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Illumina's current OCF Margin % of 26.49% is 457.1% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Illumina and its competitors. For the Medical Diagnostics & Research industry, the median OCF Margin % is 4.76 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Illumina's current OCF Margin % is 26.49%, which is near median its own 10-year median of 27.25. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Illumina stock overvalued right now?
Based on GuruFocus' analysis, Illumina (MIL:1ILMN) is currently considered Significantly Overvalued. The stock's GF Value™ is €104.58, compared to a current price of €143.82 — trading 37.5% above its estimated fair value. The current OCF Margin % is 26.49%, which is near median its 10-year median of 27.25 and 457.1% above the Medical Diagnostics & Research industry median of 4.76. Illumina's overall GF Score™ is 49/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For Illumina (MIL:1ILMN), the current OCF Margin % is 26.49% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Illumina (MIL:1ILMN) Overvalued in 2026?
Based on GuruFocus' analysis, Illumina stock appears to be overvalued.
The current stock price of €143.82 is trading 37.5% above its estimated GF Value™ of €104.58.
GuruFocus considers Illumina to be Significantly Overvalued.
Key valuation signals for MIL:1ILMN:
OCF Margin %: 26.49% (near median its 10-year median of 27.25)
GF Value™: €104.58 vs. price of €143.82 (37.5% above fair value)
Industry Position: 457.1% above the Medical Diagnostics & Research median (#28 of 204)
No single metric tells the full story. See the MIL:1ILMN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (9% of 2024 sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
49GF Score
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