Illumina (MIL:1ILMN) ROA %: 8.17% (As of Mar. 2026) — 20% Below Median


MIL:1ILMN Illumina Inc MIL:1ILMN
49 GF Score
Price €143.82
GF Value €104.58
Valuation Significantly Overvalued
! 7 Warning Signs
View Full Analysis

What is Illumina ROA %?

Illumina MIL:1ILMN 49 ROA % is 8.17% as of Mar. 2026, which is 20% below its 10-year median of 10.21. GuruFocus rates MIL:1ILMN with a GF Score™ of 49/100 and a GF Value™ of €104.58 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 215 Medical Diagnostics & Research companies, Illumina ranks better than 90.7% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Illumina's annualized Net Income for the quarter that ended in Mar. 2026 was €464 Mil. Illumina's average Total Assets over the quarter that ended in Mar. 2026 was €5,674 Mil. Therefore, Illumina's annualized ROA % for the quarter that ended in Mar. 2026 was 8.17%.

The historical rank and industry rank for Illumina's ROA % or its related term are showing as below:

MIL:1ILMN' s ROA % Range Over the Past 10 Years
Min: -32.07   Med: 10.21   Max: 15.22
Current: 13.48

During the past 13 years, Illumina's highest ROA % was 15.22%. The lowest was -32.07%. And the median was 10.21%.

MIL:1ILMN's ROA % is ranked better than
90.7% of 215 companies
in the Medical Diagnostics & Research industry
Industry Median: -1.87 vs MIL:1ILMN: 13.48

Illumina  (MIL:1ILMN) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=463.64/5673.7555
=(Net Income / Revenue)*(Revenue / Total Assets)
=(463.64 / 3774.86)*(3774.86 / 5673.7555)
=Net Margin %*Asset Turnover
=12.28 %*0.6653
=8.17 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Illumina ROA % Related Terms


Illumina ROA % Historical Data

* Premium members only.

The historical data trend for Illumina's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Illumina ROA % Chart

Illumina Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 6.85 -33.22 -10.22 -15.28 12.42

Illumina Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 8.26 14.82 9.70 20.86 8.17

MIL:1ILMN vs MTD, DGX, LH: ROA % Comparison

For the Diagnostics & Research subindustry, Illumina's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Illumina ROA % vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Illumina's ROA % distribution charts can be found below:

* The bar in red indicates where Illumina's ROA % falls into.


MIL:1ILMN
49GF Score
Illumina Inc MIL:1ILMN
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Illumina ROA % Calculation

Illumina's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=725.9/( (6019.365+5673.976)/ 2 )
=725.9/5846.6705
=12.42 %

Illumina's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=463.64/( (5673.976+5673.535)/ 2 )
=463.64/5673.7555
=8.17 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of 8.17% mean?
Illumina (MIL:1ILMN) has a ROA % of 8.17% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Illumina and its competitors. This is 20% below median its historical median of 10.21. According to the industry distribution chart, Illumina ranks #20 out of 215 companies in the Medical Diagnostics & Research industry, placing it in the top 9.3%.
Is Illumina's ROA % too high?
Illumina's current ROA % of 8.17% is 20% below median its 10-year median of 10.21. Based on the distribution chart, Illumina ranks #20 out of 215 companies in the Medical Diagnostics & Research industry, which is in the top quartile — a strong position relative to peers. Overall, Illumina has a GF Score™ of 49/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Illumina's ROA % compare to MTD and DGX?
According to the Medical Diagnostics & Research industry distribution chart, Illumina ranks #20 out of 215 companies for ROA %. This places Illumina in the top 9% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Medical Diagnostics & Research company?
A good ROA % depends on the Medical Diagnostics & Research industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Illumina and its competitors. Illumina's current ROA % is 8.17%, which is 20% below median its own 10-year median of 10.21. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Illumina stock overvalued right now?
Based on GuruFocus' analysis, Illumina (MIL:1ILMN) is currently considered Significantly Overvalued. The stock's GF Value™ is €104.58, compared to a current price of €143.82 — trading 37.5% above its estimated fair value. The current ROA % is 8.17%, which is 20% below median its 10-year median of 10.21. Illumina's overall GF Score™ is 49/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Illumina (MIL:1ILMN), the current ROA % is 8.17% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Illumina (MIL:1ILMN) Overvalued in 2026?

Based on GuruFocus' analysis, Illumina stock appears to be overvalued. The current stock price of €143.82 is trading 37.5% above its estimated GF Value™ of €104.58. GuruFocus considers Illumina to be Significantly Overvalued.

Key valuation signals for MIL:1ILMN:

  • ROA %: 8.17% (20% below median its 10-year median of 10.21)
  • GF Value™: €104.58 vs. price of €143.82 (37.5% above fair value)
  • GF Score™: 49/100 with 7 warning signs

No single metric tells the full story. See the MIL:1ILMN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Illumina Business Description

Address 5200 Illumina Way, San Diego, CA, USA, 92122
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (9% of 2024 sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
49GF Score

Get the complete analysis for MIL:1ILMN

ROA % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€143.82
Price
€104.58
GF Value