CAI (Caris Life Sciences) Operating Margin %: 2.44% (As of Mar. 2026)

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CAI Caris Life Sciences Inc CAI
11 GF Score
Price $15.53
! 2 Warning Signs
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What is Caris Life Sciences Operating Margin %?

Caris Life Sciences CAI -0.89% 11 Operating Margin % is 2.44% as of Mar. 2026. GuruFocus rates CAI with a GF Score™ of 11/100. The stock has 2 warning signs investors should review. Among 940 Biotechnology companies, Caris Life Sciences ranks better than 82.77% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Caris Life Sciences's Operating Income for the three months ended in Mar. 2026 was $5.3 Mil. Caris Life Sciences's Revenue for the three months ended in Mar. 2026 was $216.2 Mil. Therefore, Caris Life Sciences's Operating Margin % for the quarter that ended in Mar. 2026 was 2.44%.

The historical rank and industry rank for Caris Life Sciences's Operating Margin % or its related term are showing as below:

CAI' s Operating Margin % Range Over the Past 10 Years
Min: -122.16   Med: -83.38   Max: 11.94
Current: 11.94


CAI's Operating Margin % is ranked better than
82.77% of 940 companies
in the Biotechnology industry
Industry Median: -86.55 vs CAI: 11.94

Caris Life Sciences's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

Caris Life Sciences's Operating Income for the three months ended in Mar. 2026 was $5.3 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 was $108.3 Mil.


Caris Life Sciences  (NAS:CAI) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Caris Life Sciences Operating Margin % Related Terms


Caris Life Sciences Operating Margin % Historical Data

* Premium members only.

The historical data trend for Caris Life Sciences's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Caris Life Sciences Operating Margin % Chart

Caris Life Sciences Annual Data
Trend Dec22 Dec23 Dec24 Dec25
Operating Margin %
-122.16 -104.38 -62.37 5.56

Caris Life Sciences Quarterly Data
Dec22 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only -47.93 -9.92 15.05 30.19 2.44

CAI vs DNTH, MANE, TNGX: Operating Margin % Comparison

For the Biotechnology subindustry, Caris Life Sciences's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Caris Life Sciences Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Caris Life Sciences's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Caris Life Sciences's Operating Margin % falls into.


CAI
11GF Score
Caris Life Sciences Inc CAI
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Caris Life Sciences Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Caris Life Sciences's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=45.113 / 812.033
=5.56 %

Caris Life Sciences's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as

Operating Margin %=Operating Income (Q: Mar. 2026 ) / Revenue (Q: Mar. 2026 )
=5.282 / 216.174
=2.44 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of 2.44% mean?
Caris Life Sciences (CAI) has a Operating Margin % of 2.44% as of Mar. 2026. Operating margin is the ratio of total operating income to net sales. View historical data on Caris Life Sciences and its competitors. According to the industry distribution chart, Caris Life Sciences ranks #162 out of 940 companies in the Biotechnology industry, placing it in the top 17.2%.
Is Caris Life Sciences' Operating Margin % too high?
Caris Life Sciences' current Operating Margin % is 2.44%. Based on the distribution chart, Caris Life Sciences ranks #162 out of 940 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Caris Life Sciences has a GF Score™ of 11/100, reflecting its overall financial health beyond just this single metric.
How does Caris Life Sciences' Operating Margin % compare to DNTH and MANE?
According to the Biotechnology industry distribution chart, Caris Life Sciences ranks #162 out of 940 companies for Operating Margin %. This places Caris Life Sciences in the top 17% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Caris Life Sciences and its competitors. Caris Life Sciences's current Operating Margin % is 2.44%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Caris Life Sciences stock overvalued right now?
Caris Life Sciences (CAI) has a current Operating Margin % of 2.44%. The current Operating Margin % is 2.44%. Caris Life Sciences' overall GF Score™ is 11/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Caris Life Sciences (CAI), the current Operating Margin % is 2.44% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Caris Life Sciences Business Description

Other Exchanges CAI:Mexico49J:Germany
Address 750 W. John Carpenter Freeway, Suite 800, Irving, TX, USA, 75039
Caris Life Sciences Inc is a patient-centric, next-generation AI TechBio company. It develop and commercialize solutions to transform healthcare through the use of comprehensive molecular information and artificial intelligence/machine learning algorithms at scale.
11GF Score

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Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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