CAI (Caris Life Sciences) Return-on-Tangible-Equity: -0.36% (As of Mar. 2026)

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CAI Caris Life Sciences Inc CAI
11 GF Score
Price $15.53
! 2 Warning Signs
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What is Caris Life Sciences Return-on-Tangible-Equity?

Caris Life Sciences CAI -0.89% 11 Return-on-Tangible-Equity is -0.36% as of Mar. 2026. GuruFocus rates CAI with a GF Score™ of 11/100. The stock has 2 warning signs investors should review. Among 1,199 Biotechnology companies, Caris Life Sciences ranks better than 99.92% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. Caris Life Sciences's annualized net income for the quarter that ended in Mar. 2026 was $-2.0 Mil. Caris Life Sciences's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $566.1 Mil. Therefore, Caris Life Sciences's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was -0.36%.

The historical rank and industry rank for Caris Life Sciences's Return-on-Tangible-Equity or its related term are showing as below:

CAI' s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: 0   Med: 0   Max: 0
Current: Negative Tangible Equity

CAI's Return-on-Tangible-Equity is ranked better than
99.92% of 1199 companies
in the Biotechnology industry
Industry Median: -42.21 vs CAI: Negative Tangible Equity

Caris Life Sciences  (NAS:CAI) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


Caris Life Sciences Return-on-Tangible-Equity Related Terms


Caris Life Sciences Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for Caris Life Sciences's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Caris Life Sciences Return-on-Tangible-Equity Chart

Caris Life Sciences Annual Data
Trend Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
0.00 0.00 0.00 0.00

Caris Life Sciences Quarterly Data
Dec22 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 21.80 64.47 -0.36

CAI vs DNTH, MANE, TNGX: Return-on-Tangible-Equity Comparison

For the Biotechnology subindustry, Caris Life Sciences's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Caris Life Sciences Return-on-Tangible-Equity vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Caris Life Sciences's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where Caris Life Sciences's Return-on-Tangible-Equity falls into.


CAI
11GF Score
Caris Life Sciences Inc CAI
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
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Caris Life Sciences Return-on-Tangible-Equity Calculation

Caris Life Sciences's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-68.088/( (-2518.182+557.963 )/ 2 )
=-68.088/-980.1095
=N/A %

Caris Life Sciences's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-2.04/( (557.963+574.146)/ 2 )
=-2.04/566.0545
=-0.36 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of -0.36% mean?
Caris Life Sciences (CAI) has a Return-on-Tangible-Equity of -0.36% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Caris Life Sciences and its competitors. According to the industry distribution chart, Caris Life Sciences ranks #1 out of 1199 companies in the Biotechnology industry, placing it in the top 0.099999999999994%.
Is Caris Life Sciences' Return-on-Tangible-Equity too high?
Caris Life Sciences' current Return-on-Tangible-Equity is -0.36%. Based on the distribution chart, Caris Life Sciences ranks #1 out of 1199 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Caris Life Sciences has a GF Score™ of 11/100, reflecting its overall financial health beyond just this single metric.
How does Caris Life Sciences' Return-on-Tangible-Equity compare to DNTH and MANE?
According to the Biotechnology industry distribution chart, Caris Life Sciences ranks #1 out of 1199 companies for Return-on-Tangible-Equity. This places Caris Life Sciences in the top 0% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Caris Life Sciences and its competitors. Caris Life Sciences's current Return-on-Tangible-Equity is -0.36%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Caris Life Sciences stock overvalued right now?
Caris Life Sciences (CAI) has a current Return-on-Tangible-Equity of -0.36%. The current Return-on-Tangible-Equity is -0.36%. Caris Life Sciences' overall GF Score™ is 11/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For Caris Life Sciences (CAI), the current Return-on-Tangible-Equity is -0.36% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Caris Life Sciences Business Description

Other Exchanges CAI:Mexico49J:Germany
Address 750 W. John Carpenter Freeway, Suite 800, Irving, TX, USA, 75039
Caris Life Sciences Inc is a patient-centric, next-generation AI TechBio company. It develop and commercialize solutions to transform healthcare through the use of comprehensive molecular information and artificial intelligence/machine learning algorithms at scale.
11GF Score

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Return-on-Tangible-Equity is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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