LCTX (Lineage Cell Therapeutics) Operating Margin %: -440.17% (As of Mar. 2026)


LCTX Lineage Cell Therapeutics Inc LCTX
78 GF Score
Price $1.26
GF Value $1.33
Valuation Fairly Valued
! 4 Warning Signs
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What is Lineage Cell Therapeutics Operating Margin %?

Lineage Cell Therapeutics LCTX +0.80% 78 Operating Margin % is -440.17% as of Mar. 2026. GuruFocus rates LCTX with a GF Score™ of 78/100 and a GF Value™ of $1.33 (Fairly Valued). The stock has 4 warning signs investors should review. Among 945 Biotechnology companies, Lineage Cell Therapeutics ranks worse than 56.3% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Lineage Cell Therapeutics's Operating Income for the three months ended in Mar. 2026 was $-7.59 Mil. Lineage Cell Therapeutics's Revenue for the three months ended in Mar. 2026 was $1.73 Mil. Therefore, Lineage Cell Therapeutics's Operating Margin % for the quarter that ended in Mar. 2026 was -440.17%.

Good Sign:

Lineage Cell Therapeutics Inc operating margin is expanding. Margin expansion is usually a good sign.

The historical rank and industry rank for Lineage Cell Therapeutics's Operating Margin % or its related term are showing as below:

LCTX' s Operating Margin % Range Over the Past 10 Years
Min: -3421.35   Med: -1765.94   Max: -149.62
Current: -154.73


LCTX's Operating Margin % is ranked worse than
56.3% of 945 companies
in the Biotechnology industry
Industry Median: -86.89 vs LCTX: -154.73

Lineage Cell Therapeutics's 5-Year Average Operating Margin % Growth Rate was 43.90% per year.

Lineage Cell Therapeutics's Operating Income for the three months ended in Mar. 2026 was $-7.59 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 was $-22.87 Mil.


Lineage Cell Therapeutics  (AMEX:LCTX) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Lineage Cell Therapeutics Operating Margin % Related Terms


Lineage Cell Therapeutics Operating Margin % Historical Data

* Premium members only.

The historical data trend for Lineage Cell Therapeutics's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Lineage Cell Therapeutics Operating Margin % Chart

Lineage Cell Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -1,263.12 -153.17 -276.50 -226.11 -149.62

Lineage Cell Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -433.09 -178.66 -102.85 -99.09 -440.17

LCTX vs FATE, ABEO, RCKT: Operating Margin % Comparison

For the Biotechnology subindustry, Lineage Cell Therapeutics's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Lineage Cell Therapeutics Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Lineage Cell Therapeutics's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Lineage Cell Therapeutics's Operating Margin % falls into.


LCTX
78GF Score
Lineage Cell Therapeutics Inc LCTX
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Lineage Cell Therapeutics Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Lineage Cell Therapeutics's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-21.779 / 14.556
=-149.62 %

Lineage Cell Therapeutics's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as

Operating Margin %=Operating Income (Q: Mar. 2026 ) / Revenue (Q: Mar. 2026 )
=-7.593 / 1.725
=-440.17 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -440.17% mean?
Lineage Cell Therapeutics (LCTX) has a Operating Margin % of -440.17% as of Mar. 2026. Operating margin is the ratio of total operating income to net sales. View historical data on Lineage Cell Therapeutics and its competitors. According to the industry distribution chart, Lineage Cell Therapeutics ranks #532 out of 945 companies in the Biotechnology industry, placing it in the top 56.3%.
Is Lineage Cell Therapeutics' Operating Margin % too high?
Lineage Cell Therapeutics' current Operating Margin % is -440.17%. Based on the distribution chart, Lineage Cell Therapeutics ranks #532 out of 945 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Lineage Cell Therapeutics has a GF Score™ of 78/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Lineage Cell Therapeutics' Operating Margin % compare to FATE and ABEO?
According to the Biotechnology industry distribution chart, Lineage Cell Therapeutics ranks #532 out of 945 companies for Operating Margin %. This places Lineage Cell Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Lineage Cell Therapeutics and its competitors. Lineage Cell Therapeutics's current Operating Margin % is -440.17%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Lineage Cell Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Lineage Cell Therapeutics (LCTX) is currently considered Fairly Valued. The stock's GF Value™ is $1.33, compared to a current price of $1.26 — trading 5.3% below its estimated fair value. The current Operating Margin % is -440.17%. Lineage Cell Therapeutics' overall GF Score™ is 78/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Lineage Cell Therapeutics (LCTX), the current Operating Margin % is -440.17% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Lineage Cell Therapeutics (LCTX) Overvalued in 2026?

Based on GuruFocus' analysis, Lineage Cell Therapeutics stock appears to be undervalued. The current stock price of $1.26 is trading 5.3% below its estimated GF Value™ of $1.33. GuruFocus considers Lineage Cell Therapeutics to be Fairly Valued.

Key valuation signals for LCTX:

  • Operating Margin %: -440.17%
  • GF Value™: $1.33 vs. price of $1.26 (5.3% below fair value)
  • GF Score™: 78/100 with 4 warning signs

No single metric tells the full story. See the LCTX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Lineage Cell Therapeutics Business Description

Other Exchanges LCTX:IsraelBT3:Germany
Address 2173 Salk Avenue, Suite 200, Carlsbad, CA, USA, 92008
Lineage Cell Therapeutics Inc is a clinical-stage biotechnology company focused on the development and commercialization of novel therapies for the treatment of degenerative diseases. The company's pipeline currently includes: OpRegen, OPC1, ReSonance, ILT1, RND1, PNC1, and LCT-CON. Its programs are based on its proprietary, in-house, cell-based manufacturing platform, which it call AlloSCOPE (Allogeneic, Scalable, Consistent, Off-the-shelf, Pluripotent Cell Engineering), and supported by its associated development, formulation, manufacturing, and delivery capabilities. The AlloSCOPE platform is a proprietary differentiation and production modality from which, a single, well-characterized pluripotent cell line can create a stable current Good Manufacturing Practice, master cell bank.
78GF Score

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Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.26
Price
$1.33
GF Value