STTK (Shattuck Labs) Operating Margin %: 0.00% (As of Mar. 2026)

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STTK Shattuck Labs Inc STTK
42 GF Score
Price $7.42
GF Value $1.05
Valuation Significantly Overvalued
! 6 Warning Signs
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What is Shattuck Labs Operating Margin %?

Shattuck Labs STTK +4.80% 42 Operating Margin % is 0.00% as of Mar. 2026. GuruFocus rates STTK with a GF Score™ of 42/100 and a GF Value™ of $1.05 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 940 Biotechnology companies, Shattuck Labs ranks worse than 90.11% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Shattuck Labs's Operating Income for the three months ended in Mar. 2026 was $-15.55 Mil. Shattuck Labs's Revenue for the three months ended in Mar. 2026 was $0.00 Mil. Therefore, Shattuck Labs's Operating Margin % for the quarter that ended in Mar. 2026 was 0.00%.

Warning Sign:

Shattuck Labs Inc operating margin has been in a 5-year decline. The average rate of decline per year is -71.1%.

The historical rank and industry rank for Shattuck Labs's Operating Margin % or its related term are showing as below:

STTK' s Operating Margin % Range Over the Past 10 Years
Min: -15848.01   Med: -890.02   Max: -27.4
Current: -5266.4


STTK's Operating Margin % is ranked worse than
90.11% of 940 companies
in the Biotechnology industry
Industry Median: -86.55 vs STTK: -5266.40

Shattuck Labs's 5-Year Average Operating Margin % Growth Rate was -71.10% per year.

Shattuck Labs's Operating Income for the three months ended in Mar. 2026 was $-15.55 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 was $-52.66 Mil.


Shattuck Labs  (NAS:STTK) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Shattuck Labs Operating Margin % Related Terms


Shattuck Labs Operating Margin % Historical Data

* Premium members only.

The historical data trend for Shattuck Labs's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Shattuck Labs Operating Margin % Chart

Shattuck Labs Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial -150.81 -15,848.01 -5,549.61 -1,408.27 -5,150.80

Shattuck Labs Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 -1,071.60 0.00 0.00

STTK vs ACHV, CRMD, EIKN: Operating Margin % Comparison

For the Biotechnology subindustry, Shattuck Labs's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Shattuck Labs Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Shattuck Labs's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Shattuck Labs's Operating Margin % falls into.


STTK
42GF Score
Shattuck Labs Inc STTK
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Shattuck Labs Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Shattuck Labs's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-51.508 / 1
=-5,150.80 %

Shattuck Labs's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as

Operating Margin %=Operating Income (Q: Mar. 2026 ) / Revenue (Q: Mar. 2026 )
=-15.545 / 0
= %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of 0.00% mean?
Shattuck Labs (STTK) has a Operating Margin % of 0.00% as of Mar. 2026. Operating margin is the ratio of total operating income to net sales. View historical data on Shattuck Labs and its competitors. According to the industry distribution chart, Shattuck Labs ranks #847 out of 940 companies in the Biotechnology industry, placing it in the top 90.1%.
Is Shattuck Labs' Operating Margin % too high?
Shattuck Labs' current Operating Margin % is 0.00%. Based on the distribution chart, Shattuck Labs ranks #847 out of 940 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Shattuck Labs has a GF Score™ of 42/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Shattuck Labs' Operating Margin % compare to ACHV and CRMD?
According to the Biotechnology industry distribution chart, Shattuck Labs ranks #847 out of 940 companies for Operating Margin %. This places Shattuck Labs in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Shattuck Labs and its competitors. Shattuck Labs's current Operating Margin % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Shattuck Labs stock overvalued right now?
Based on GuruFocus' analysis, Shattuck Labs (STTK) is currently considered Significantly Overvalued. The stock's GF Value™ is $1.05, compared to a current price of $7.42 — trading 606.7% above its estimated fair value. The current Operating Margin % is 0.00%. Shattuck Labs' overall GF Score™ is 42/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Shattuck Labs (STTK), the current Operating Margin % is 0.00% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Shattuck Labs (STTK) Overvalued in 2026?

Based on GuruFocus' analysis, Shattuck Labs stock appears to be overvalued. The current stock price of $7.42 is trading 606.7% above its estimated GF Value™ of $1.05. GuruFocus considers Shattuck Labs to be Significantly Overvalued.

Key valuation signals for STTK:

  • Operating Margin %: 0.00%
  • GF Value™: $1.05 vs. price of $7.42 (606.7% above fair value)
  • GF Score™: 42/100 with 6 warning signs

No single metric tells the full story. See the STTK stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Shattuck Labs Business Description

Address 500 W. 5th Street, Suite 1200, Austin, TX, USA, 78701
Shattuck Labs Inc is a biotechnology company specializing in the development of potential treatments for inflammatory and immune-mediated diseases. It is developing a potentially first-in-class antibody for the treatment of inflammatory bowel disease (IBD) and other inflammatory and immune-mediated diseases. The company's expertise in protein engineering and the development of novel tumor necrosis factor (TNF) receptor therapeutics comes together in its main program, SL-325, which has the potential to be a first-in-class death receptor 3 (DR3) antagonist antibody. In addition, the company is developing SL-425, a half-life extended version of SL-325, and multiple other preclinical DR3-based bispecific antibodies, for the treatment of patients with IBD.
42GF Score

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Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$7.42
Price
$1.05
GF Value