STTK (Shattuck Labs) Operating Income: $-52.66 Mil (TTM As of Mar. 2026)

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STTK Shattuck Labs Inc STTK
42 GF Score
Price $7.42
GF Value $1.05
Valuation Significantly Overvalued
! 6 Warning Signs
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What is Shattuck Labs Operating Income?

Shattuck Labs STTK +4.80% 42 Operating Income is $-52.66 Mil as of Mar. 2026. GuruFocus rates STTK with a GF Score™ of 42/100 and a GF Value™ of $1.05 (Significantly Overvalued). The stock has 6 warning signs investors should review.

Shattuck Labs's Operating Income for the three months ended in Mar. 2026 was $-15.55 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 was $-52.66 Mil.

Operating Margin % is calculated as Operating Income divided by its Revenue. Shattuck Labs's Operating Income for the three months ended in Mar. 2026 was $-15.55 Mil. Shattuck Labs's Revenue for the three months ended in Mar. 2026 was $0.00 Mil. Therefore, Shattuck Labs's Operating Margin % for the quarter that ended in Mar. 2026 was %.

Warning Sign:

Shattuck Labs Inc operating margin has been in a 5-year decline. The average rate of decline per year is -71.1%.

Shattuck Labs's 5-Year average Growth Rate for Operating Margin % was -71.10% per year.

Operating Income or EBIT is linked to Return on Capital for both regular definition and Joel Greenblatt's definition. Shattuck Labs's annualized ROC % for the quarter that ended in Mar. 2026 was -547.89%. Shattuck Labs's annualized ROC (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was -1,084.50%.


Shattuck Labs  (NAS:STTK) Operating Income Explanation

1. Operating Income or EBIT is linked to Return on Capital for both regular definition and Joel Greenblatt's definition.

Shattuck Labs's annualized ROC % for the quarter that ended in Mar. 2026 is calculated as:

ROC % (Q: Mar. 2026 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Dec. 2025 ) + Invested Capital (Q: Mar. 2026 ))/ count )
=-62.18 * ( 1 - 0% )/( (12.391 + 10.307)/ 2 )
=-62.18/11.349
=-547.89 %

where

Note: The Operating Income data used here is four times the quarterly (Mar. 2026) data.

2. Joel Greenblatt's definition of Return on Capital:

Shattuck Labs's annualized ROC (Joel Greenblatt) % for the quarter that ended in Mar. 2026 is calculated as:

ROC (Joel Greenblatt) %(Q: Mar. 2026 )
=EBIT/Average of (Net fixed Assets + Net Working Capital)
=EBIT/Average of (Property, Plant and Equipment+Net Working Capital)
     Q: Dec. 2025  Q: Mar. 2026
=EBIT/( ( (Property, Plant and Equipment + Net Working Capital) + (Property, Plant and Equipment + Net Working Capital) )/ count )
=-62.18/( ( (6.114 + max(-1.805, 0)) + (5.353 + max(-0.062999999999997, 0)) )/ 2 )
=-62.18/( ( 6.114 + 5.353 )/ 2 )
=-62.18/5.7335
=-1,084.50 %

where Working Capital is:

Working Capital(Q: Dec. 2025 )
=(Accounts Receivable + Total Inventories + Other Current Assets) - (Accounts Payable & Accrued Expense + Defer. Rev. + Other Current Liabilities)
=(0 + 0 + 4.41) - (3.212 + 0 + 3.003)
=-1.805

Working Capital(Q: Mar. 2026 )
=(Accounts Receivable + Total Inventories + Other Current Assets) - (Accounts Payable & Accrued Expense + Defer. Rev. + Other Current Liabilities)
=(0 + 0 + 3.334) - (2.31 + 0 + 1.087)
=-0.062999999999997

When net working capital is negative, 0 is used.

Note: The EBIT data used here is four times the quarterly (Mar. 2026) EBIT data.

3. Operating Income is also linked to Operating Margin %:

Shattuck Labs's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as:

Operating Margin %=Operating Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-15.545/0
= %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

4. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Operating Income growth rate using Operating Income per share data.


Be Aware

Compared with a company's EBITDA margin, Operating Margin can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin may decline. Often the Operating Margin declines well before the company's revenue or even profit decline. Therefore, Operating Margin is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia's Operating Margin had already been in decline since 2002, although its earnings per share were still rising. Investors who paid attention to Operating Margin would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Shattuck Labs Operating Income Related Terms


Shattuck Labs Operating Income Historical Data

* Premium members only.

The historical data trend for Shattuck Labs's Operating Income can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Shattuck Labs Operating Income Chart

Shattuck Labs Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Income
Get a 7-Day Free Trial -45.27 -103.33 -91.96 -80.57 -51.51

Shattuck Labs Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Operating Income Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -14.39 -13.03 -10.72 -13.37 -15.55
STTK
42GF Score
Shattuck Labs Inc STTK
Operating Income is just one metric. See GF Score™, valuation, warning signs, and more.
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Shattuck Labs Operating Income Calculation

Operating Income, is the profit a company earned through operations. All expenses, including cash expenses such as cost of goods sold (COGS), research & development, wages, and non-cash expenses, such as depreciation, depletion and amortization, have been deducted from the sales.

Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-52.66 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Income →
What does a Operating Income of $-52.66 Mil mean?
Shattuck Labs (STTK) has a Operating Income of $-52.66 Mil as of Mar. 2026. Operating Income equals sales less all operating expenses. It is linked to EBIT. View historical data on Shattuck Labs and its competitors.
Is Shattuck Labs' Operating Income too high?
Shattuck Labs' current Operating Income is $-52.66 Mil. Overall, Shattuck Labs has a GF Score™ of 42/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Shattuck Labs' Operating Income compare to ACHV and CRMD?
Shattuck Labs' Operating Income of $-52.66 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Income for a Biotechnology company?
A good Operating Income depends on the Biotechnology industry context. However, Operating Income should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Income mean?
A high Operating Income can signal that a stock is expensive relative to its fundamentals. Operating Income equals sales less all operating expenses. It is linked to EBIT. View historical data on Shattuck Labs and its competitors. Shattuck Labs's current Operating Income is $-52.66 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Shattuck Labs stock overvalued right now?
Based on GuruFocus' analysis, Shattuck Labs (STTK) is currently considered Significantly Overvalued. The stock's GF Value™ is $1.05, compared to a current price of $7.42 — trading 606.7% above its estimated fair value. The current Operating Income is $-52.66 Mil. Shattuck Labs' overall GF Score™ is 42/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Income calculated?
Operating Income is calculated from a company's financial statements. For Shattuck Labs (STTK), the current Operating Income is $-52.66 Mil as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Shattuck Labs (STTK) Overvalued in 2026?

Based on GuruFocus' analysis, Shattuck Labs stock appears to be overvalued. The current stock price of $7.42 is trading 606.7% above its estimated GF Value™ of $1.05. GuruFocus considers Shattuck Labs to be Significantly Overvalued.

Key valuation signals for STTK:

  • Operating Income: $-52.66 Mil
  • GF Value™: $1.05 vs. price of $7.42 (606.7% above fair value)
  • GF Score™: 42/100 with 6 warning signs

No single metric tells the full story. See the STTK stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Shattuck Labs Business Description

Address 500 W. 5th Street, Suite 1200, Austin, TX, USA, 78701
Shattuck Labs Inc is a biotechnology company specializing in the development of potential treatments for inflammatory and immune-mediated diseases. It is developing a potentially first-in-class antibody for the treatment of inflammatory bowel disease (IBD) and other inflammatory and immune-mediated diseases. The company's expertise in protein engineering and the development of novel tumor necrosis factor (TNF) receptor therapeutics comes together in its main program, SL-325, which has the potential to be a first-in-class death receptor 3 (DR3) antagonist antibody. In addition, the company is developing SL-425, a half-life extended version of SL-325, and multiple other preclinical DR3-based bispecific antibodies, for the treatment of patients with IBD.
42GF Score

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Operating Income is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$7.42
Price
$1.05
GF Value