XORTX TherapeuticsXRTX +4.27%30 PB Ratio is 2.39 as of Jun. 25, 2026. GuruFocus rates XRTX with a GF Score™ of 30/100. The stock has 1 warning sign investors should review. Among 1,233 Biotechnology companies, XORTX Therapeutics ranks better than 57.5% on this metric.
The historical rank and industry rank for XORTX Therapeutics's PB Ratio or its related term are showing as below:
XRTX'
s PB Ratio Range Over the Past 10 Years
Min: 0 Med: 0 Max: 2.42
Current: 2.42
During the past 11 years, XORTX Therapeutics's highest PB Ratio was 2.42. The lowest was 0.00. And the median was 0.00.
XRTX's PB Ratio is ranked better than 57.5% of 1233
companies
in the Biotechnology industry
Industry Median: 2.8
vs XRTX: 2.42
During the past 12 months, XORTX Therapeutics's average Book Value Per Share Growth Rate was -69.80% per year.
During the past 3 years, the average Book Value Per Share Growth Rate was -58.30% per year.
During the past 5 years, the average Book Value Per Share Growth Rate was -32.90% per year.
During the past 11 years, the highest 3-Year average Book Value Per Share Growth Rate of XORTX Therapeutics was 180.00% per year. The lowest was -58.30% per year. And the median was 2.60% per year.
Back to Basics: PB Ratio
XORTX Therapeutics (NAS:XRTX) PB Ratio Explanation
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
XORTX Therapeutics PB Ratio Related Terms
XORTX Therapeutics PB Ratio Historical Data
* Premium members only.
The historical data trend for XORTX Therapeutics's PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, XORTX Therapeutics's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
XORTX Therapeutics PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, XORTX Therapeutics's PB Ratio distribution charts can be found below:
* The bar in red indicates where XORTX Therapeutics's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
XORTX Therapeutics (XRTX) has a PB Ratio of 2.39 as of Jun. 25, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on XORTX Therapeutics and its competitors. According to the industry distribution chart, XORTX Therapeutics ranks #524 out of 1233 companies in the Biotechnology industry, placing it in the top 42.5%.
Is XORTX Therapeutics' PB Ratio too high?
XORTX Therapeutics' current PB Ratio is 2.39. The Biotechnology industry median PB Ratio is 2.80. XORTX Therapeutics' value of 2.39 is 14.6% below this industry median. Based on the distribution chart, XORTX Therapeutics ranks #524 out of 1233 companies in the Biotechnology industry, which is above the industry midpoint. Overall, XORTX Therapeutics has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does XORTX Therapeutics' PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, XORTX Therapeutics ranks #524 out of 1233 companies for PB Ratio. This puts XORTX Therapeutics in the upper half of its industry. The industry median PB Ratio is 2.80. XORTX Therapeutics' value of 2.39 is 14.6% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.80, based on 1,233 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. XORTX Therapeutics's current PB Ratio of 2.39 is 14.6% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on XORTX Therapeutics and its competitors. For the Biotechnology industry, the median PB Ratio is 2.80 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. XORTX Therapeutics's current PB Ratio is 2.39. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is XORTX Therapeutics stock overvalued right now?
XORTX Therapeutics (XRTX) has a current PB Ratio of 2.39. The current PB Ratio is 2.39 and 14.6% below the Biotechnology industry median of 2.80. XORTX Therapeutics' overall GF Score™ is 30/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For XORTX Therapeutics (XRTX), the current PB Ratio is 2.39 as of Jun. 25, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
XORTX Therapeutics Inc is a clinical-stage pharmaceutical company focused on developing therapies to treat gout and progressive kidney disease modulated by aberrant purine and uric acid metabolism in orphan disease indications such as allopurinol-intolerant gout and autosomal dominant polycystic kidney disease, as well as more prevalent type 2 diabetic nephropathy and fatty liver disease. Its focus is on developing products to slow and/or reverse the progression of these diseases. The Company operates in one reportable operating segment: the development and commercialization of therapies to treat hyperuricemia-related diseases.
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