PHIO (Phio Pharmaceuticals) Return-on-Tangible-Asset: -82.33% (As of Mar. 2026)


PHIO Phio Pharmaceuticals Corp PHIO
28 GF Score
Price $1.02
! 1 Warning Sign
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What is Phio Pharmaceuticals Return-on-Tangible-Asset?

Phio Pharmaceuticals PHIO -0.97% 28 Return-on-Tangible-Asset is -82.33% as of Mar. 2026. GuruFocus rates PHIO with a GF Score™ of 28/100. The stock has 1 warning sign investors should review. Among 1,413 Biotechnology companies, Phio Pharmaceuticals ranks worse than 71.13% on this metric.

Return-on-Tangible-Asset is calculated as Net Income divided by its average total tangible assets. Total tangible assets equals to Total Assets minus Intangible Assets. Phio Pharmaceuticals's annualized Net Income for the quarter that ended in Mar. 2026 was $-16.01 Mil. Phio Pharmaceuticals's average total tangible assets for the quarter that ended in Mar. 2026 was $19.45 Mil. Therefore, Phio Pharmaceuticals's annualized Return-on-Tangible-Asset for the quarter that ended in Mar. 2026 was -82.33%.

The historical rank and industry rank for Phio Pharmaceuticals's Return-on-Tangible-Asset or its related term are showing as below:

PHIO' s Return-on-Tangible-Asset Range Over the Past 10 Years
Min: -142.35   Med: -74.89   Max: -60.45
Current: -72.74

During the past 13 years, Phio Pharmaceuticals's highest Return-on-Tangible-Asset was -60.45%. The lowest was -142.35%. And the median was -74.89%.

PHIO's Return-on-Tangible-Asset is ranked worse than
71.13% of 1413 companies
in the Biotechnology industry
Industry Median: -35.77 vs PHIO: -72.74

Phio Pharmaceuticals  (NAS:PHIO) Return-on-Tangible-Asset Explanation

Return-on-Tangible-Asset measures the rate of return on the average total tangible assets (total assets minus intangible assets). Tangible means physical in nature. Intangible Assets are assets that are not physical in nature, and typically "derive their value from legal or intellectual rights." Return-on-Tangible-Asset measures a firm's efficiency at generating profits from its tangible assets. It shows how well a company uses what it has to generate earnings. Return-on-Tangible-Assets can vary drastically across industries. Therefore, Return-on-Tangible-Asset should not be used to compare companies in different industries.


Be Aware

Like ROE and ROA, Return-on-Tangible-Asset is calculated with only 12 months data. Fluctuations in the company’s earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. Return-on-Tangible-Asset can be affected by events such as stock buyback or issuance, and by a company’s tax rate and its interest payment. Return-on-Tangible-Asset may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high Return-on-Tangible-Asset may indicate vulnerability in the durability of the competitive advantage.


Phio Pharmaceuticals Return-on-Tangible-Asset Related Terms


Phio Pharmaceuticals Return-on-Tangible-Asset Historical Data

* Premium members only.

The historical data trend for Phio Pharmaceuticals's Return-on-Tangible-Asset can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Phio Pharmaceuticals Return-on-Tangible-Asset Chart

Phio Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Asset
Get a 7-Day Free Trial Premium Member Only Premium Member Only -64.96 -60.45 -97.63 -94.69 -63.90

Phio Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Asset Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -73.79 -70.04 -83.91 -57.49 -82.33

PHIO vs PBM, KPRX, OSRH: Return-on-Tangible-Asset Comparison

For the Biotechnology subindustry, Phio Pharmaceuticals's Return-on-Tangible-Asset, along with its competitors' market caps and Return-on-Tangible-Asset data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Phio Pharmaceuticals Return-on-Tangible-Asset vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Phio Pharmaceuticals's Return-on-Tangible-Asset distribution charts can be found below:

* The bar in red indicates where Phio Pharmaceuticals's Return-on-Tangible-Asset falls into.


PHIO
28GF Score
Phio Pharmaceuticals Corp PHIO
Return-on-Tangible-Asset is just one metric. See GF Score™, valuation, warning signs, and more.
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Phio Pharmaceuticals Return-on-Tangible-Asset Calculation

Phio Pharmaceuticals's annualized Return-on-Tangible-Asset for the fiscal year that ended in Dec. 2025 is calculated as:

Return-on-Tangible-Asset=Net Income/( (Total Tangible Assets+Total Tangible Assets)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Assets - Intangible Assets+Total Assets - Intangible Assets)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-8.698/( (5.738+21.487)/ 2 )
=-8.698/13.6125
=-63.90 %

Phio Pharmaceuticals's annualized Return-on-Tangible-Asset for the quarter that ended in Mar. 2026 is calculated as:

Return-on-Tangible-Asset=Net Income/( (Total Tangible Assets+Total Tangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Assets - Intangible Assets+Total Assets - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-16.012/( (21.487+17.412)/ 2 )
=-16.012/19.4495
=-82.33 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Asset, the net income of the last fiscal year and the average total tangible assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data.

What does a Return-on-Tangible-Asset of -82.33% mean?
Phio Pharmaceuticals (PHIO) has a Return-on-Tangible-Asset of -82.33% as of Mar. 2026. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on Phio Pharmaceuticals and its competitors. According to the industry distribution chart, Phio Pharmaceuticals ranks #1005 out of 1413 companies in the Biotechnology industry, placing it in the top 71.1%.
Is Phio Pharmaceuticals' Return-on-Tangible-Asset too high?
Phio Pharmaceuticals' current Return-on-Tangible-Asset is -82.33%. Based on the distribution chart, Phio Pharmaceuticals ranks #1005 out of 1413 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Phio Pharmaceuticals has a GF Score™ of 28/100, reflecting its overall financial health beyond just this single metric.
How does Phio Pharmaceuticals' Return-on-Tangible-Asset compare to PBM and KPRX?
According to the Biotechnology industry distribution chart, Phio Pharmaceuticals ranks #1005 out of 1413 companies for Return-on-Tangible-Asset. This places Phio Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Asset for a Biotechnology company?
A good Return-on-Tangible-Asset depends on the Biotechnology industry context. However, Return-on-Tangible-Asset should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Asset mean?
A high Return-on-Tangible-Asset can signal that a stock is expensive relative to its fundamentals. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on Phio Pharmaceuticals and its competitors. Phio Pharmaceuticals's current Return-on-Tangible-Asset is -82.33%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Phio Pharmaceuticals stock overvalued right now?
Phio Pharmaceuticals (PHIO) has a current Return-on-Tangible-Asset of -82.33%. The current Return-on-Tangible-Asset is -82.33%. Phio Pharmaceuticals' overall GF Score™ is 28/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Asset calculated?
Return-on-Tangible-Asset is calculated from a company's financial statements. For Phio Pharmaceuticals (PHIO), the current Return-on-Tangible-Asset is -82.33% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Phio Pharmaceuticals Business Description

Address 411 Swedeland Road, Suite 23-1080, King of Prussia, PA, USA, 19406
Phio Pharmaceuticals Corp is a clinical-stage biopharmaceutical company whose proprietary INTASYL small-interfering RNA gene silencing technology is designed to make immune cells more effective in killing tumor cells. Its pipeline programs are PH-762 and PH-894. The group is developing therapeutics that are designed to leverage INTASYL to precisely target specific proteins that reduce the body's ability to fight cancer, without the need for specialized formulations or drug delivery systems. It is committed to discovering and developing cancer treatments for patients by creating new pathways toward a cancer-free future. The Company operates with a single operating segment, the Clinical segment, and all assets are located in the United States.
28GF Score

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