PMN (ProMIS Neurosciences) Return-on-Tangible-Asset: -86.11% (As of Mar. 2026)

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PMN ProMIS Neurosciences Inc PMN
34 GF Score
Price $13.30
! 2 Warning Signs
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What is ProMIS Neurosciences Return-on-Tangible-Asset?

ProMIS Neurosciences PMN -5.03% 34 Return-on-Tangible-Asset is -86.11% as of Mar. 2026. GuruFocus rates PMN with a GF Score™ of 34/100. The stock has 2 warning signs investors should review. Among 1,416 Biotechnology companies, ProMIS Neurosciences ranks worse than 89.34% on this metric.

Return-on-Tangible-Asset is calculated as Net Income divided by its average total tangible assets. Total tangible assets equals to Total Assets minus Intangible Assets. ProMIS Neurosciences's annualized Net Income for the quarter that ended in Mar. 2026 was $-32.98 Mil. ProMIS Neurosciences's average total tangible assets for the quarter that ended in Mar. 2026 was $38.30 Mil. Therefore, ProMIS Neurosciences's annualized Return-on-Tangible-Asset for the quarter that ended in Mar. 2026 was -86.11%.

The historical rank and industry rank for ProMIS Neurosciences's Return-on-Tangible-Asset or its related term are showing as below:

PMN' s Return-on-Tangible-Asset Range Over the Past 10 Years
Min: -408.1   Med: -294.91   Max: 17.09
Current: -167.54

During the past 13 years, ProMIS Neurosciences's highest Return-on-Tangible-Asset was 17.09%. The lowest was -408.10%. And the median was -294.91%.

PMN's Return-on-Tangible-Asset is ranked worse than
89.34% of 1416 companies
in the Biotechnology industry
Industry Median: -35.76 vs PMN: -167.54

ProMIS Neurosciences  (NAS:PMN) Return-on-Tangible-Asset Explanation

Return-on-Tangible-Asset measures the rate of return on the average total tangible assets (total assets minus intangible assets). Tangible means physical in nature. Intangible Assets are assets that are not physical in nature, and typically "derive their value from legal or intellectual rights." Return-on-Tangible-Asset measures a firm's efficiency at generating profits from its tangible assets. It shows how well a company uses what it has to generate earnings. Return-on-Tangible-Assets can vary drastically across industries. Therefore, Return-on-Tangible-Asset should not be used to compare companies in different industries.


Be Aware

Like ROE and ROA, Return-on-Tangible-Asset is calculated with only 12 months data. Fluctuations in the company’s earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. Return-on-Tangible-Asset can be affected by events such as stock buyback or issuance, and by a company’s tax rate and its interest payment. Return-on-Tangible-Asset may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high Return-on-Tangible-Asset may indicate vulnerability in the durability of the competitive advantage.


ProMIS Neurosciences Return-on-Tangible-Asset Related Terms


ProMIS Neurosciences Return-on-Tangible-Asset Historical Data

* Premium members only.

The historical data trend for ProMIS Neurosciences's Return-on-Tangible-Asset can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

ProMIS Neurosciences Return-on-Tangible-Asset Chart

ProMIS Neurosciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Asset
Get a 7-Day Free Trial Premium Member Only Premium Member Only -104.30 -146.71 -128.75 17.09 -282.77

ProMIS Neurosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Asset Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -180.55 -349.52 -299.16 -278.69 -86.11

PMN vs BMEA, ANIX, ATRA: Return-on-Tangible-Asset Comparison

For the Biotechnology subindustry, ProMIS Neurosciences's Return-on-Tangible-Asset, along with its competitors' market caps and Return-on-Tangible-Asset data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


ProMIS Neurosciences Return-on-Tangible-Asset vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, ProMIS Neurosciences's Return-on-Tangible-Asset distribution charts can be found below:

* The bar in red indicates where ProMIS Neurosciences's Return-on-Tangible-Asset falls into.


PMN
34GF Score
ProMIS Neurosciences Inc PMN
Return-on-Tangible-Asset is just one metric. See GF Score™, valuation, warning signs, and more.
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ProMIS Neurosciences Return-on-Tangible-Asset Calculation

ProMIS Neurosciences's annualized Return-on-Tangible-Asset for the fiscal year that ended in Dec. 2025 is calculated as:

Return-on-Tangible-Asset=Net Income/( (Total Tangible Assets+Total Tangible Assets)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Assets - Intangible Assets+Total Assets - Intangible Assets)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-39.719/( (18.911+9.182)/ 2 )
=-39.719/14.0465
=-282.77 %

ProMIS Neurosciences's annualized Return-on-Tangible-Asset for the quarter that ended in Mar. 2026 is calculated as:

Return-on-Tangible-Asset=Net Income/( (Total Tangible Assets+Total Tangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Assets - Intangible Assets+Total Assets - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-32.976/( (9.182+67.412)/ 2 )
=-32.976/38.297
=-86.11 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Asset, the net income of the last fiscal year and the average total tangible assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data.

What does a Return-on-Tangible-Asset of -86.11% mean?
ProMIS Neurosciences (PMN) has a Return-on-Tangible-Asset of -86.11% as of Mar. 2026. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on ProMIS Neurosciences and its competitors. According to the industry distribution chart, ProMIS Neurosciences ranks #1265 out of 1416 companies in the Biotechnology industry, placing it in the top 89.3%.
Is ProMIS Neurosciences' Return-on-Tangible-Asset too high?
ProMIS Neurosciences' current Return-on-Tangible-Asset is -86.11%. Based on the distribution chart, ProMIS Neurosciences ranks #1265 out of 1416 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, ProMIS Neurosciences has a GF Score™ of 34/100, reflecting its overall financial health beyond just this single metric.
How does ProMIS Neurosciences' Return-on-Tangible-Asset compare to BMEA and ANIX?
According to the Biotechnology industry distribution chart, ProMIS Neurosciences ranks #1265 out of 1416 companies for Return-on-Tangible-Asset. This places ProMIS Neurosciences in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Asset for a Biotechnology company?
A good Return-on-Tangible-Asset depends on the Biotechnology industry context. However, Return-on-Tangible-Asset should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Asset mean?
A high Return-on-Tangible-Asset can signal that a stock is expensive relative to its fundamentals. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on ProMIS Neurosciences and its competitors. ProMIS Neurosciences's current Return-on-Tangible-Asset is -86.11%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is ProMIS Neurosciences stock overvalued right now?
ProMIS Neurosciences (PMN) has a current Return-on-Tangible-Asset of -86.11%. The current Return-on-Tangible-Asset is -86.11%. ProMIS Neurosciences' overall GF Score™ is 34/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Asset calculated?
Return-on-Tangible-Asset is calculated from a company's financial statements. For ProMIS Neurosciences (PMN), the current Return-on-Tangible-Asset is -86.11% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

ProMIS Neurosciences Business Description

Other Exchanges 23J:Germany
Address 1920 Yonge Street, Suite 200, Toronto, ON, CAN, M4S 3E2
ProMIS Neurosciences Inc is a clinical-stage biotechnology company focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimers disease (AD), amyotrophic lateral sclerosis (ALS), and multiple system atrophy (MSA). The company applies its thermodynamic, computational discovery platform, ProMIS, and Collective Coordinates to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Compnies product candidates are PMN310, PMN267, and PMN442. Lead product candidate is PMN310, a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 is companies second lead product candidate targeting ALS.
34GF Score

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Return-on-Tangible-Asset is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$13.30
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