PMN (ProMIS Neurosciences) ROE % Adjusted to Book Value: -59.00% (As of Mar. 2026)


PMN ProMIS Neurosciences Inc PMN
30 GF Score
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What is ProMIS Neurosciences ROE % Adjusted to Book Value?

ProMIS Neurosciences PMN +22.42% 30 ROE % Adjusted to Book Value is -59.00% as of Mar. 2026. GuruFocus rates PMN with a GF Score™ of 30/100. The stock has 2 warning signs investors should review.

ProMIS Neurosciences's ROE % for the quarter that ended in Mar. 2026 was -110.92%. ProMIS Neurosciences's PB Ratio for the quarter that ended in Mar. 2026 was 1.88. ProMIS Neurosciences's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -59.00%.

ProMIS Neurosciences ROE % Adjusted to Book Value Related Terms

ProMIS Neurosciences ROE % Adjusted to Book Value Historical Data

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The historical data trend for ProMIS Neurosciences's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

ProMIS Neurosciences ROE % Adjusted to Book Value Chart

ProMIS Neurosciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only -46.33 0.00 -190.09 14.61 0.00

ProMIS Neurosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -94.35 0.00 -422.59 0.00 -59.00

PMN vs BMEA, ANIX, ATRA: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, ProMIS Neurosciences's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

ProMIS Neurosciences ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, ProMIS Neurosciences's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where ProMIS Neurosciences's ROE % Adjusted to Book Value falls into.


PMN
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ProMIS Neurosciences Inc PMN
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ProMIS Neurosciences ROE % Adjusted to Book Value Calculation

ProMIS Neurosciences's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-521.62% / N/A
=N/A

ProMIS Neurosciences's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-110.92% / 1.88
=-59.00%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -59.00% mean?
ProMIS Neurosciences (PMN) has a ROE % Adjusted to Book Value of -59.00% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on ProMIS Neurosciences and its competitors.
Is ProMIS Neurosciences' ROE % Adjusted to Book Value too high?
ProMIS Neurosciences' current ROE % Adjusted to Book Value is -59.00%. Overall, ProMIS Neurosciences has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does ProMIS Neurosciences' ROE % Adjusted to Book Value compare to BMEA and ANIX?
ProMIS Neurosciences' ROE % Adjusted to Book Value of -59.00% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on ProMIS Neurosciences and its competitors. ProMIS Neurosciences's current ROE % Adjusted to Book Value is -59.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is ProMIS Neurosciences stock overvalued right now?
ProMIS Neurosciences (PMN) has a current ROE % Adjusted to Book Value of -59.00%. The current ROE % Adjusted to Book Value is -59.00%. ProMIS Neurosciences' overall GF Score™ is 30/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For ProMIS Neurosciences (PMN), the current ROE % Adjusted to Book Value is -59.00% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

ProMIS Neurosciences Business Description

Other Exchanges 23J:Germany
Address 1920 Yonge Street, Suite 200, Toronto, ON, CAN, M4S 3E2
ProMIS Neurosciences Inc is a clinical-stage biotechnology company focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimers disease (AD), amyotrophic lateral sclerosis (ALS), and multiple system atrophy (MSA). The company applies its thermodynamic, computational discovery platform, ProMIS, and Collective Coordinates to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Compnies product candidates are PMN310, PMN267, and PMN442. Lead product candidate is PMN310, a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 is companies second lead product candidate targeting ALS.
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